Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes T Jourdan, G Godlewski, R Cinar, A Bertola, G Szanda, J Liu, J Tam, ... Nature medicine 19 (9), 1132-1140, 2013 | 410 | 2013 |
Peripheral cannabinoid-1 receptor inverse agonism reduces obesity by reversing leptin resistance J Tam, R Cinar, J Liu, G Godlewski, D Wesley, T Jourdan, G Szanda, ... Cell metabolism 16 (2), 167-179, 2012 | 370 | 2012 |
CB1 antagonism exerts specific molecular effects on visceral and subcutaneous fat and reverses liver steatosis in diet-induced obese mice T Jourdan, L Djaouti, L Demizieux, J Gresti, B Verges, P Degrace Diabetes 59 (4), 926-934, 2010 | 198 | 2010 |
Hepatic cannabinoid-1 receptors mediate diet-induced insulin resistance by increasingde novosynthesis of long-chain ceramides R Cinar, G Godlewski, J Liu, J Tam, T Jourdan, B Mukhopadhyay, ... Hepatology 59 (1), 143-153, 2014 | 172 | 2014 |
Overactive cannabinoid 1 receptor in podocytes drives type 2 diabetic nephropathy T Jourdan, G Szanda, AZ Rosenberg, J Tam, BJ Earley, G Godlewski, ... Proceedings of the National Academy of Sciences 111 (50), E5420-E5428, 2014 | 140 | 2014 |
Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase J Liu, R Cinar, K Xiong, G Godlewski, T Jourdan, Y Lin, JM Ntambi, ... Proceedings of the National Academy of Sciences 110 (47), 18832-18837, 2013 | 83 | 2013 |
Hybrid inhibitor of peripheral cannabinoid-1 receptors and inducible nitric oxide synthase mitigates liver fibrosis R Cinar, MR Iyer, Z Liu, Z Cao, T Jourdan, K Erdelyi, G Godlewski, ... JCI insight 1 (11), 2016 | 77 | 2016 |
Antagonism of peripheral hepatic cannabinoid receptor‐1 improves liver lipid metabolism in mice: evidence from cultured explants T Jourdan, L Demizieux, J Gresti, L Djaouti, L Gaba, B Vergès, P Degrace Hepatology 55 (3), 790-799, 2012 | 74 | 2012 |
Cannabinoid CB1 receptor overactivity contributes to the pathogenesis of idiopathic pulmonary fibrosis R Cinar, BR Gochuico, MR Iyer, T Jourdan, T Yokoyama, JK Park, ... JCI insight 2 (8), 2017 | 70 | 2017 |
Endocannabinoid regulation of β‐cell functions: implications for glycaemic control and diabetes T Jourdan, G Godlewski, G Kunos Diabetes, Obesity and Metabolism 18 (6), 549-557, 2016 | 65 | 2016 |
Gene expression and protein content in relation to intramuscular fat content in Muscovy and Pekin ducks G Saez, S Davail, G Gentes, JF Hocquette, T Jourdan, P Degrace, ... Poultry Science 88 (11), 2382-2391, 2009 | 62 | 2009 |
Cannabinoid‐1 receptor deletion in podocytes mitigates both glomerular and tubular dysfunction in a mouse model of diabetic nephropathy T Jourdan, JK Park, ZV Varga, J Pálóczi, NJ Coffey, AZ Rosenberg, ... Diabetes, Obesity and Metabolism 20 (3), 698-708, 2018 | 60 | 2018 |
Regulation of lipid flux between liver and adipose tissue during transient hepatic steatosis in carnitine-depleted rats P Degrace, L Demizieux, Z Du, J Gresti, L Caverot, L Djaouti, T Jourdan, ... Journal of Biological Chemistry 282 (29), 20816-20826, 2007 | 56 | 2007 |
Role of adiponectin in the metabolic effects of cannabinoid type 1 receptor blockade in mice with diet-induced obesity J Tam, G Godlewski, BJ Earley, L Zhou, T Jourdan, G Szanda, R Cinar, ... American Journal of Physiology-Endocrinology and Metabolism 306 (4), E457-E468, 2014 | 55 | 2014 |
Targeting liver aldehyde dehydrogenase-2 prevents heavy but not moderate alcohol drinking A Guillot, T Ren, T Jourdan, RJ Pawlosky, E Han, SJ Kim, L Zhang, ... Proceedings of the National Academy of Sciences 116 (51), 25974-25981, 2019 | 54 | 2019 |
Disruption of renal arginine metabolism promotes kidney injury in hepatorenal syndrome in mice ZV Varga, K Erdelyi, J Paloczi, R Cinar, ZK Zsengeller, T Jourdan, ... Hepatology 68 (4), 1519-1533, 2018 | 54 | 2018 |
Developmental role of macrophage cannabinoid-1 receptor signaling in type 2 diabetes T Jourdan, G Szanda, R Cinar, G Godlewski, DJ Holovac, JK Park, ... Diabetes 66 (4), 994-1007, 2017 | 47 | 2017 |
Targeting peripheral CB1 receptors reduces ethanol intake via a gut-brain axis G Godlewski, R Cinar, NJ Coffey, J Liu, T Jourdan, B Mukhopadhyay, ... Cell metabolism 29 (6), 1320-1333. e8, 2019 | 46 | 2019 |
Liver carbohydrate and lipid metabolism of insulin-deficient mice is altered by trans-10, cis-12 conjugated linoleic acid T Jourdan, L Djaouti, L Demizieux, J Gresti, B Verges, P Degrace The Journal of nutrition 139 (10), 1901-1907, 2009 | 43 | 2009 |
Decreasing CB1 receptor signaling in Kupffer cells improves insulin sensitivity in obese mice T Jourdan, SM Nicoloro, Z Zhou, Y Shen, J Liu, NJ Coffey, R Cinar, ... Molecular metabolism 6 (11), 1517-1528, 2017 | 41 | 2017 |