Full atomistic model of prion structure and conversion G Spagnolli, M Rigoli, S Orioli, AM Sevillano, P Faccioli, H Wille, E Biasini, ... PLoS pathogens 15 (7), e1007864, 2019 | 126 | 2019 |
Pharmacological inactivation of the prion protein by targeting a folding intermediate G Spagnolli, T Massignan, A Astolfi, S Biggi, M Rigoli, P Brunelli, ... Communications Biology 4 (1), 62, 2021 | 44 | 2021 |
Atomic detail of protein folding revealed by an ab initio reappraisal of circular dichroism A Ianeselli, S Orioli, G Spagnolli, P Faccioli, L Cupellini, S Jurinovich, ... Journal of the American Chemical Society 140 (10), 3674-3682, 2018 | 43 | 2018 |
All-atom simulations reveal how single-point mutations promote serpin misfolding F Wang, S Orioli, A Ianeselli, G Spagnolli, S a Beccara, A Gershenson, ... Biophysical journal 114 (9), 2083-2094, 2018 | 27* | 2018 |
The cellular prion protein beyond prion diseases G Manni, V Lewis, M Senesi, G Spagnolli, F Fallarino, S Collins, ... Swiss Medical Weekly 150, w20222, 2020 | 22 | 2020 |
Defective cyclophilin A induces TDP-43 proteinopathy: implications for amyotrophic lateral sclerosis and frontotemporal dementia L Pasetto, M Grassano, S Pozzi, S Luotti, E Sammali, A Migazzi, M Basso, ... Brain 144 (12), 3710-3726, 2021 | 19 | 2021 |
Modeling PrPSc Generation Through Deformed Templating G Spagnolli, M Rigoli, G Novi Inverardi, YB Codeseira, E Biasini, ... Frontiers in bioengineering and biotechnology 8, 590501, 2020 | 19 | 2020 |
All-atom simulation of the HET-s prion replication L Terruzzi, G Spagnolli, A Boldrini, JR Requena, E Biasini, P Faccioli PLOS Computational Biology 16 (9), e1007922, 2020 | 13 | 2020 |
The Compelling Demand for an Effective PrPC-Directed Therapy against Prion Diseases A Astolfi, G Spagnolli, E Biasini, ML Barreca ACS Medicinal Chemistry Letters 11 (11), 2063-2067, 2020 | 12 | 2020 |
Understanding prion structure and conversion G Spagnolli, JR Requena, E Biasini Progress in Molecular Biology and Translational Science 175, 19-30, 2020 | 10 | 2020 |
Ok google, how could i design therapeutics against prion diseases? M Rigoli, G Spagnolli, P Faccioli, JR Requena, E Biasini Current opinion in pharmacology 44, 39-45, 2019 | 9 | 2019 |
Antimalarial Artefenomel Inhibits Human SARS-CoV-2 Replication in Cells while Suppressing the Receptor ACE2 T Massignan, A Boldrini, L Terruzzi, G Spagnolli, A Astolfi, V Bonaldo, ... arXiv preprint arXiv:2004.13493, 2020 | 7 | 2020 |
Long-range allostery mediates the regulation of plasminogen activator inhibitor-1 by cell adhesion factor vitronectin K Kihn, E Marchiori, G Spagnolli, A Boldrini, L Terruzzi, DA Lawrence, ... Journal of Biological Chemistry 298 (12), 2022 | 4* | 2022 |
Structural features of an infectious recombinant PrPSc prion using solid state NMR M Martín-Pastor, YB Codeseira, G Spagnolli, H Eraña, LC Fernández, ... bioRxiv, 2020.04. 08.032839, 2020 | 4 | 2020 |
Structural Basis of Mutation-Dependent p53 Tetramerization Deficiency M Rigoli, G Spagnolli, G Lorengo, P Monti, R Potestio, E Biasini, A Inga International Journal of Molecular Sciences 23 (14), 7960, 2022 | 2 | 2022 |
Solid state NMR reveals a parallel in register architecture for an infectious recombinant prion M Martín-Pastor, YB Codeseira, G Spagnolli, H Eraña, LC Fernández, ... bioRxiv, 2021.07. 20.453078, 2021 | 2 | 2021 |
All-atom calculation of protein free-energy profiles S Orioli, A Ianeselli, G Spagnolli, P Faccioli The Journal of Chemical Physics 147 (15), 2017 | 2 | 2017 |
Pliability in the m6A-Binding Region Extends Druggability of YTH Domains G Cazzanelli, A Dalle Vedove, G Spagnolli, L Terruzzi, E Colasurdo, ... Journal of Chemical Information and Modeling, 2024 | 1 | 2024 |
Identification of the zebrafish homologues of IMPG2, a retinal proteoglycan ME Castellini, G Spagnolli, L Poggi, E Biasini, S Casarosa, A Messina Cell and Tissue Research 394 (1), 93-105, 2023 | 1 | 2023 |
Folding, Misfolding and Therapeutics in Prion Diseases G Spagnolli Università degli studi di Trento, 2021 | | 2021 |