Trends in GPCR drug discovery: new agents, targets and indications AS Hauser, MM Attwood, M Rask-Andersen, HB Schiöth, DE Gloriam Nature reviews Drug discovery 16 (12), 829-842, 2017 | 2319 | 2017 |
Trends in kinase drug discovery: targets, indications and inhibitor design MM Attwood, D Fabbro, AV Sokolov, S Knapp, HB Schiöth Nature Reviews Drug Discovery 20 (11), 839-861, 2021 | 444 | 2021 |
Recent developments of HDAC inhibitors: Emerging indications and novel molecules AD Bondarev, MM Attwood, J Jonsson, VN Chubarev, VV Tarasov, ... British journal of clinical pharmacology 87 (12), 4577-4597, 2021 | 237 | 2021 |
Acylcarnitines: nomenclature, biomarkers, therapeutic potential, drug targets, and clinical trials M Dambrova, M Makrecka-Kuka, J Kuka, R Vilskersts, D Nordberg, ... Pharmacological Reviews 74 (3), 506-551, 2022 | 159 | 2022 |
Trends in antidiabetic drug discovery: FDA approved drugs, new drugs in clinical trials and global sales AD Dahlén, G Dashi, I Maslov, MM Attwood, J Jonsson, V Trukhan, ... Frontiers in Pharmacology 12, 807548, 2022 | 128 | 2022 |
Advances in the development of new biomarkers for Alzheimer’s disease TO Klyucherev, P Olszewski, AA Shalimova, VN Chubarev, VV Tarasov, ... Translational neurodegeneration 11 (1), 25, 2022 | 110 | 2022 |
Soluble ligands as drug targets MM Attwood, J Jonsson, M Rask-Andersen, HB Schiöth Nature Reviews Drug Discovery 19 (10), 695-710, 2020 | 75 | 2020 |
Heterologous expression, biosynthetic studies, and ecological function of the selective Gq‐signaling inhibitor FR900359 M Crüsemann, R Reher, I Schamari, AO Brachmann, T Ohbayashi, ... Angewandte Chemie International Edition 57 (3), 836-840, 2018 | 72 | 2018 |
Orphan drugs and their impact on pharmaceutical development MM Attwood, M Rask-Andersen, HB Schiöth Trends in pharmacological sciences 39 (6), 525-535, 2018 | 63 | 2018 |
Pharmacological treatment of migraine: Drug classes, mechanisms of action, clinical trials and new treatments F Zobdeh, A Ben Kraiem, MM Attwood, VN Chubarev, VV Tarasov, ... British journal of pharmacology 178 (23), 4588-4607, 2021 | 52 | 2021 |
A MIR4646 associated methylation locus is hypomethylated in adolescent depression AE Boström, DM Ciuculete, M Attwood, R Krattinger, L Nikontovic, ... Journal of affective disorders 220, 117-128, 2017 | 26 | 2017 |
Opportunities and challenges for drug discovery in modulating Adhesion G protein-coupled receptor (GPCR) functions AD Bondarev, MM Attwood, J Jonsson, VN Chubarev, VV Tarasov, ... Expert Opinion on Drug Discovery 15 (11), 1291-1307, 2020 | 23 | 2020 |
Recent developments of phosphodiesterase inhibitors: Clinical trials, emerging indications and novel molecules AD Bondarev, MM Attwood, J Jonsson, VN Chubarev, VV Tarasov, W Liu, ... Frontiers in pharmacology 13, 1057083, 2022 | 21 | 2022 |
Topology based identification and comprehensive classification of four-transmembrane helix containing proteins (4TMs) in the human genome MM Attwood, A Krishnan, V Pivotti, S Yazdi, MS Almén, HB Schiöth BMC genomics 17, 1-16, 2016 | 16 | 2016 |
Highly diversified expansions shaped the evolution of membrane bound proteins in metazoans MM Attwood, A Krishnan, MS Almén, HB Schiöth Scientific reports 7 (1), 12387, 2017 | 14 | 2017 |
Brain cancer drug discovery: clinical trials, drug classes, targets, and combinatorial therapies AV Sokolov, SA Dostdar, MM Attwood, AA Krasilnikova, AA Ilina, ... Pharmacological reviews 73 (4), 1172-1203, 2021 | 13 | 2021 |
Characterization of five transmembrane proteins: with focus on the Tweety, Sideroflexin, and YIP1 domain families MM Attwood, HB Schiöth Frontiers in Cell and Developmental Biology 9, 708754, 2021 | 9 | 2021 |
The regulatory role of AP-2β in monoaminergic neurotransmitter systems: insights on its signalling pathway, linked disorders and theragnostic potential MH Al-Sabri, M Nikpour, LE Clemensson, MM Attwood, MJ Williams, ... Cell & Bioscience 12 (1), 151, 2022 | 2 | 2022 |
Heterologe Expression, Biosynthese und ökologische Funktion des selektiven Gq‐Signaltransduktionsinhibitors FR900359 M Crüsemann, R Reher, I Schamari, AO Brachmann, T Ohbayashi, ... Angewandte Chemie 130 (3), 844-849, 2018 | 2 | 2018 |
Classification of Trispanins: A Diverse Group of Proteins That Function in Membrane Synthesis and Transport Mechanisms MM Attwood, HB Schiöth Frontiers in Cell and Developmental Biology 7, 386, 2020 | | 2020 |