| Template-directed synthesis of a genetic polymer in a model protocell SS Mansy, JP Schrum, M Krishnamurthy, S Tobé, DA Treco, JW Szostak Nature 454 (7200), 122-125, 2008 | 767 | 2008 |
| Engineered nucleic acids encoding a modified erythropoietin and their expression JP Schrum, NB Afeyan, GJ Sieczkiewicz, S Bancel, A De Fougerolles, ... US Patent 8,710,200, 2014 | 433 | 2014 |
| Engineered nucleic acids and methods of use thereof JP Schrum, S Bancel, NB Afeyan US Patent 8,822,663, 2014 | 352 | 2014 |
| The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation U Basu, J Chaudhuri, C Alpert, S Dutt, S Ranganath, G Li, JP Schrum, ... Nature 438 (7067), 508-511, 2005 | 341 | 2005 |
| Modified polynucleotides for the production of secreted proteins T Chakraborty, A De Fougerolles US Patent 9,192,651, 2015 | 315* | 2015 |
| Modified polynucleotides for the production of biologics and proteins associated with human disease S Bancel, T Chakraborty, A De Fougerolles, SM Elbashir, M John, A Roy, ... US Patent 8,999,380, 2015 | 298 | 2015 |
| The origins of cellular life JP Schrum, TF Zhu, JW Szostak Cold Spring Harbor perspectives in biology 2 (9), a002212, 2010 | 298 | 2010 |
| Modified polynucleotides for the production of proteins associated with human disease S Bancel, T Chakraborty, A De Fougerolles, SM Elbashir, M John, A Roy, ... US Patent App. 13/791,910, 2014 | 250 | 2014 |
| In vivo production of proteins S Bancel, T Chakraborty, A De Fougerolles, SM Elbashir, M John, A Roy, ... US Patent 9,221,891, 2015 | 234 | 2015 |
| Engineered nucleic acids and methods of use thereof S Bancel, JP Schrum, A Aristarkhov US Patent 9,464,124, 2016 | 233 | 2016 |
| Modified nucleoside, nucleotide, and nucleic acid compositions A De Fougerolles, KM Wood, SM Elbashir, NB Afeyan, P Valencia, ... US Patent App. 13/917,720, 2013 | 233 | 2013 |
| Modified nucleosides, nucleotides, and nucleic acids, and uses thereof JP Schrum, S Siddiqi, K Ejebe US Patent 9,334,328, 2016 | 229 | 2016 |
| Engineered nucleic acids and methods of use thereof J Schrum, GJ Sieczkiewicz, K Ejebe, SM Elbashir US Patent App. 13/252,049, 2012 | 215 | 2012 |
| Modified nucleosides, nucleotides, and nucleic acids, and uses thereof A De Fougerolles, A Roy, JP Schrum, S Siddiqi, P Hatala, S Bancel US Patent 9,428,535, 2016 | 208 | 2016 |
| DLIN-KC2-DMA lipid nanoparticle delivery of modified polynucleotides A De Fougerolles, KM Wood, SM Elbashir, JP Schrum US Patent 8,754,062, 2014 | 208 | 2014 |
| Modified nucleoside, nucleotide, and nucleic acid compositions A De Fougerolles, KM Wood, SM Elbashir, NB Afeyan, P Valencia, ... US Patent App. 13/714,458, 2013 | 204 | 2013 |
| Modified polynucleotides for the production of proteins S Bancel, T Chakraborty, A De Fougerolles, SM Elbashir, M John, A Roy, ... US Patent 9,254,311, 2016 | 194 | 2016 |
| Modified nucleosides, nucleotides, and nucleic acids, and uses thereof JP Schrum US Patent App. 13/481,127, 2013 | 178 | 2013 |
| Modified polynucleotides A De Fougerolles, J Guild US Patent 10,501,512, 2019 | 163 | 2019 |
| Modified polynucleotides for the production of factor ix A De Fougerolles, SM Elbashir, JP Schrum US Patent App. 13/897,362, 2013 | 162 | 2013 |
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