SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation X Wang, RS Lee, BH Alver, JR Haswell, S Wang, J Mieczkowski, Y Drier, ... Nature genetics 49 (2), 289-295, 2017 | 327 | 2017 |
MNase titration reveals differences between nucleosome occupancy and chromatin accessibility J Mieczkowski, A Cook, SK Bowman, B Mueller, BH Alver, S Kundu, ... Nature communications 7 (1), 11485, 2016 | 266* | 2016 |
Single-cell RNA sequencing reveals functional heterogeneity of glioma-associated brain macrophages N Ochocka, P Segit, KA Walentynowicz, K Wojnicki, S Cyranowski, ... Nature communications 12 (1), 1151, 2021 | 258 | 2021 |
The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microglia P Przanowski, M Dabrowski, A Ellert-Miklaszewska, M Kloss, ... Journal of molecular medicine 92, 239-254, 2014 | 200 | 2014 |
Widespread changes in nucleosome accessibility without changes in nucleosome occupancy during a rapid transcriptional induction B Mueller, J Mieczkowski, S Kundu, P Wang, R Sadreyev, MY Tolstorukov, ... Genes & development 31 (5), 451-462, 2017 | 106 | 2017 |
Enhancer regions show high histone H3. 3 turnover that changes during differentiation AM Deaton, M Gomez-Rodriguez, J Mieczkowski, MY Tolstorukov, ... elife 5, e15316, 2016 | 99 | 2016 |
Immune microenvironment of experimental rat C6 gliomas resembles human glioblastomas A Gieryng, D Pszczolkowska, K Bocian, M Dabrowski, WD Rajan, M Kloss, ... Scientific reports 7 (1), 17556, 2017 | 87 | 2017 |
Novel proteins regulated by mTOR in subependymal giant cell astrocytomas of patients with tuberous sclerosis complex and new therapeutic implications ME Tyburczy, K Kotulska, P Pokarowski, J Mieczkowski, J Kucharska, ... The American Journal of Pathology 176 (4), 1878-1890, 2010 | 82 | 2010 |
Down-regulation of IKKβ expression in glioma-infiltrating microglia/macrophages is associated with defective inflammatory/immune gene responses in glioblastoma J Mieczkowski, M Kocyk, P Nauman, K Gabrusiewicz, M Sielska, ... Oncotarget 6 (32), 33077, 2015 | 78 | 2015 |
Environmental stimuli shape microglial plasticity in glioma S Garofalo, A Porzia, F Mainiero, S Di Angelantonio, B Cortese, B Basilico, ... Elife 6, e33415, 2017 | 56 | 2017 |
In search for reliable markers of glioma-induced polarization of microglia KA Walentynowicz, N Ochocka, M Pasierbinska, K Wojnicki, K Stepniak, ... Frontiers in immunology 9, 1329, 2018 | 51 | 2018 |
Probe set filtering increases correlation between Affymetrix GeneChip and qRT-PCR expression measurements J Mieczkowski, ME Tyburczy, M Dabrowski, P Pokarowski BMC bioinformatics 11, 1-10, 2010 | 49 | 2010 |
Novel small molecular inhibitors disrupt the JAK/STAT3 and FAK signaling pathways and exhibit a potent antitumor activity in glioma cells K Swiatek-Machado, J Mieczkowski, A Ellert-Miklaszewska, P Swierk, ... Cancer biology & therapy 13 (8), 657-670, 2012 | 47 | 2012 |
EGFR/FOXO3a/BIM signaling pathway determines chemosensitivity of BMP4-differentiated glioma stem cells to temozolomide IA Ciechomska, B Gielniewski, B Wojtas, B Kaminska, J Mieczkowski Experimental & molecular medicine 52 (8), 1326-1340, 2020 | 36 | 2020 |
Injury-induced perivascular niche supports alternative differentiation of adult rodent CNS progenitor cells J Ulanska-Poutanen, J Mieczkowski, C Zhao, K Konarzewska, B Kaza, ... Elife 7, e30325, 2018 | 32 | 2018 |
Mapping chromatin accessibility and active regulatory elements reveals pathological mechanisms in human gliomas K Stępniak, MA Machnicka, J Mieczkowski, A Macioszek, B Wojtaś, ... Nature Communications 12 (1), 3621, 2021 | 29 | 2021 |
Search for novel STAT3-dependent genes reveals SERPINA3 as a new STAT3 target that regulates invasion of human melanoma cells DW Kulesza, K Ramji, M Maleszewska, J Mieczkowski, M Dabrowski, ... Laboratory Investigation 99 (11), 1607-1621, 2019 | 29 | 2019 |
Identification of pathway deregulation–gene expression based analysis of consistent signal transduction J Mieczkowski, K Swiatek-Machado, B Kaminska PLoS One 7 (7), e41541, 2012 | 26 | 2012 |
Integration of genome-wide of Stat3 binding and epigenetic modification mapping with transcriptome reveals novel Stat3 target genes in glioma cells M Kruczyk, P Przanowski, M Dabrowski, K Swiatek-Machado, ... Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1839 (11 …, 2014 | 22 | 2014 |
4-1BBL–containing leukemic extracellular vesicles promote immunosuppressive effector regulatory T cells J Swatler, L Turos-Korgul, M Brewinska-Olchowik, S De Biasi, W Dudka, ... Blood Advances 6 (6), 1879-1894, 2022 | 20 | 2022 |