RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods TR Cech, AJ Zaug, MD Been US Patent 4,987,071, 1991 | 811 | 1991 |
A pseudoknot-like structure required for efficient self-cleavage of hepatitis delta virus RNA AT Perrotta, MD Been Nature 350 (6317), 434-436, 1991 | 463 | 1991 |
The Tetrahymena ribozyme acts like an RNA restriction endonuclease AJ Zaug, MD Been, TR Cech Nature 324 (6096), 429-433, 1986 | 434 | 1986 |
Imidazole rescue of a cytosine mutation in a self-cleaving ribozyme AT Perrotta, I Shih, MD Been Science 286 (5437), 123-126, 1999 | 358 | 1999 |
Rna ribozyme polymerases, dephosphorylases, restriction endoribo-nucleases and methods TR Cech, AJ Zaug, MD Been US Patent 5,093,246, 1992 | 336 | 1992 |
One binding site determines sequence specificity of Tetrahymena pre-rRNA self-splicing, trans-splicing, and RNA enzyme activity MD Been, TR Cech Cell 47 (2), 207-216, 1986 | 309 | 1986 |
Nucleotide sequence preference at rat liver and wheat germ type 1 DNA topoisomerase breakage sites in duplex SV40 DNA MD Been, RR Burgess, JJ Champoux Nucleic acids research 12 (7), 3097-3114, 1984 | 278 | 1984 |
Self‐cleaving ribozymes of hepatitis delta virus RNA MD Been, GS Wickham European journal of biochemistry 247 (3), 741-753, 1997 | 239 | 1997 |
Exon circularization in mammalian nuclear extracts. Z Pasman, MD Been, MA Garcia-Blanco Rna 2 (6), 603, 1996 | 214 | 1996 |
The self-cleaving domain from the genomic RNA of hepatitis delta virus: sequence requirements and the effects of denaturant AT Perrotta, MD Been Nucleic acids research 18 (23), 6821-6827, 1990 | 208 | 1990 |
Cleavage of oligoribonucleotides by a ribozyme derived from the hepatitis. delta. virus RNA sequence AT Perrotta, MD Been Biochemistry 31 (1), 16-21, 1992 | 172 | 1992 |
Catalytic strategies of the hepatitis delta virus ribozymes I Shih, MD Been Annual review of biochemistry 71 (1), 887-917, 2002 | 165 | 2002 |
RNA as an RNA polymerase: net elongation of an RNA primer catalyzed by the Tetrahymena ribozyme MD Been, TR Cech Science 239 (4846), 1412-1416, 1988 | 164 | 1988 |
Numerous group I introns with variable distributions in the ribosomal DNA of a lichen fungus PT DePriest, MD Been Journal of molecular biology 228 (2), 315-321, 1992 | 157 | 1992 |
Group I permuted intron-exon (PIE) sequences self-splice to produce circular exons M Puttaraju, M Been Nucleic acids research 20 (20), 5357-5364, 1992 | 151 | 1992 |
Group I intron self-splicing with adenosine: evidence for a single nucleoside-binding site MD Been, AT Perrotta Science 252 (5004), 434-437, 1991 | 145 | 1991 |
Involvement of a cytosine side chain in proton transfer in the rate-determining step of ribozyme self-cleavage I Shih, MD Been Proceedings of the National Academy of Sciences 98 (4), 1489-1494, 2001 | 141 | 2001 |
Secondary structure of the self-cleaving RNA of hepatitis delta virus: applications to catalytic RNA design MD Been, AT Perrotta, SP Rosenstein Biochemistry 31 (47), 11843-11852, 1992 | 134 | 1992 |
DNA breakage and closure by rat liver type 1 topoisomerase: separation of the half-reactions by using a single-stranded DNA substrate. MD Been, JJ Champoux Proceedings of the National Academy of Sciences 78 (5), 2883-2887, 1981 | 131 | 1981 |
A nested double pseudoknot is required for self-cleavage activity of both the genomic and antigenomic hepatitis delta virus ribozymes TS WADKINS, AT PERROTTA, AR FERRÉ-D'AMARÉ, JA DOUDNA, ... Rna 5 (6), 720-727, 1999 | 128 | 1999 |