Polymorphic family of injected pseudokinases is paramount in Toxoplasma virulence ML Reese, GM Zeiner, JPJ Saeij, JC Boothroyd, JP Boyle Proceedings of the National Academy of Sciences 108 (23), 9625-9630, 2011 | 291 | 2011 |
A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties JM Murphy, Q Zhang, SN Young, ML Reese, FP Bailey, PA Eyers, ... Biochemical Journal 457 (2), 323-334, 2014 | 281 | 2014 |
Toxoplasma rhoptry protein 16 (ROP16) subverts host function by direct tyrosine phosphorylation of STAT6 YC Ong, ML Reese, JC Boothroyd Journal of Biological Chemistry 285 (37), 28731-28740, 2010 | 266 | 2010 |
The assembly of lipid droplets and their roles in challenged cells WM Henne, ML Reese, JM Goodman The EMBO journal 37 (12), e98947, 2018 | 245 | 2018 |
A Toxoplasma gondii Pseudokinase Inhibits Host IRG Resistance Proteins MC Fleckenstein, ML Reese, S Könen-Waisman, JC Boothroyd, ... PLoS biology 10 (7), e1001358, 2012 | 180 | 2012 |
A single-cell RNA-seq atlas of Schistosoma mansoni identifies a key regulator of blood feeding G Wendt, L Zhao, R Chen, C Liu, AJ O’Donoghue, CR Caffrey, ML Reese, ... Science 369 (6511), 1644-1649, 2020 | 139 | 2020 |
A Helical Membrane‐Binding Domain Targets the Toxoplasma ROP2 Family to the Parasitophorous Vacuole ML Reese, JC Boothroyd Traffic 10 (10), 1458-1470, 2009 | 97 | 2009 |
A conserved non-canonical motif in the pseudoactive site of the ROP5 pseudokinase domain mediates its effect on Toxoplasma virulence ML Reese, JC Boothroyd Journal of Biological Chemistry 286 (33), 29366-29375, 2011 | 90 | 2011 |
The Toxoplasma pseudokinase ROP5 is an allosteric inhibitor of the immunity-related GTPases ML Reese, N Shah, JC Boothroyd Journal of Biological Chemistry 289 (40), 27849-27858, 2014 | 86 | 2014 |
Chemical genetic screen identifies Toxoplasma DJ-1 as a regulator of parasite secretion, attachment, and invasion CI Hall, ML Reese, E Weerapana, MA Child, PW Bowyer, VE Albrow, ... Proceedings of the National Academy of Sciences 108 (26), 10568-10573, 2011 | 71 | 2011 |
The guanylate kinase domain of the MAGUK PSD-95 binds dynamically to a conserved motif in MAP1a ML Reese, S Dakoji, DS Bredt, V Dötsch Nature structural & molecular biology 14 (2), 155-163, 2007 | 65 | 2007 |
Clathrin light and heavy chain interface: α-helix binding superhelix loops via critical tryptophans CY Chen, ML Reese, PK Hwang, N Ota, D Agard, FM Brodsky The EMBO Journal 21 (22), 6072-6082, 2002 | 61 | 2002 |
The coccidian parasites Toxoplasma and Neospora dysregulate mammalian lipid droplet biogenesis X Hu, D Binns, ML Reese Journal of Biological Chemistry 292 (26), 11009-11020, 2017 | 57 | 2017 |
Divergent kinase regulates membrane ultrastructure of the Toxoplasma parasitophorous vacuole T Beraki, X Hu, M Broncel, JC Young, WJ O’Shaughnessy, D Borek, ... Proceedings of the National Academy of Sciences 116 (13), 6361-6370, 2019 | 55 | 2019 |
Ancient MAPK ERK7 is regulated by an unusual inhibitory scaffold required for Toxoplasma apical complex biogenesis PS Back, WJ O’Shaughnessy, AS Moon, PS Dewangan, X Hu, J Sha, ... Proceedings of the National Academy of Sciences 117 (22), 12164-12173, 2020 | 44 | 2020 |
Loss of a conserved MAPK causes catastrophic failure in assembly of a specialized cilium-like structure in Toxoplasma gondii WJ O’Shaughnessy, X Hu, T Beraki, M McDougal, ML Reese Molecular Biology of the Cell 31 (9), 881-888, 2020 | 39 | 2020 |
Fast mapping of protein-protein interfaces by NMR spectroscopy ML Reese, V Dötsch Journal of the American Chemical Society 125 (47), 14250-14251, 2003 | 37 | 2003 |
Virulence without catalysis: how can a pseudokinase affect host cell signaling? ML Reese, JP Boyle Trends in Parasitology 28 (2), 53-57, 2012 | 33 | 2012 |
Third-generation sequencing revises the molecular karyotype for Toxoplasma gondii and identifies emerging copy number variants in sexual recombinants J Xia, A Venkat, RE Bainbridge, ML Reese, KG Le Roch, F Ay, JP Boyle Genome research 31 (5), 834-851, 2021 | 32 | 2021 |
Impact of regulated secretion on antiparasitic CD8 T cell responses HS Grover, HH Chu, FD Kelly, SJ Yang, ML Reese, N Blanchard, ... Cell reports 7 (5), 1716-1728, 2014 | 31 | 2014 |