Carbonic anhydrase IX, a hypoxia-induced catalytic component of the pH regulating machinery in tumors O Sedlakova, E Svastova, M Takacova, J Kopacek, J Pastorek, ... Frontiers in physiology 4, 400, 2014 | 210 | 2014 |
Carbonic anhydrase IX interacts with bicarbonate transporters in lamellipodia and increases cell migration via its catalytic domain E Svastova, W Witarski, L Csaderova, I Kosik, L Skvarkova, A Hulikova, ... Journal of Biological Chemistry 287 (5), 3392-3402, 2012 | 192 | 2012 |
Phosphorylation of carbonic anhydrase IX controls its ability to mediate extracellular acidification in hypoxic tumors P Ditte, F Dequiedt, E Svastova, A Hulikova, A Ohradanova-Repic, ... Cancer research 71 (24), 7558-7567, 2011 | 156 | 2011 |
Alternative splicing variant of the hypoxia marker carbonic anhydrase IX expressed independently of hypoxia and tumour phenotype M Barathova, M Takacova, T Holotnakova, A Gibadulinova, ... British journal of cancer 98 (1), 129-136, 2008 | 115 | 2008 |
Physiological expression of the gene for PrP-like protein, PrPLP/Dpl, by brain endothelial cells and its ectopic expression in neurons of PrP-deficient mice ataxic due to … A Li, S Sakaguchi, K Shigematsu, R Atarashi, BC Roy, R Nakaoke, ... The American journal of pathology 157 (5), 1447-1452, 2000 | 114 | 2000 |
The genome of herpesvirus of turkeys: comparative analysis with Marek’s disease viruses BF Kingham, V Zelnık, J Kopáček, V Majerčiak, E Ney, CJ Schmidt Journal of general virology 82 (5), 1123-1135, 2001 | 113 | 2001 |
The effect of carbonic anhydrase IX on focal contacts during cell spreading and migration L Csaderova, M Debreova, P Radvak, M Stano, M Vrestiakova, J Kopacek, ... Frontiers in physiology 4, 271, 2013 | 104 | 2013 |
Extracellular acidosis elevates carbonic anhydrase IX in human glioblastoma cells via transcriptional modulation that does not depend on hypoxia R Ihnatko, M Kubes, M Takacova, O Sedlakova, J Sedlak, J Pastorek, ... International journal of oncology 29 (4), 1025-1033, 2006 | 101 | 2006 |
Identification of a novel gene encoding a PrP-like protein expressed as chimeric transcripts fused to PrP exon 1/2 in ataxic mouse line with a disrupted PrP gene A Li, S Sakaguchi, R Atarashi, BC Roy, R Nakaoke, K Arima, N Okimura, ... Cellular and molecular neurobiology 20, 553-567, 2000 | 96 | 2000 |
MAPK pathway contributes to density-and hypoxia-induced expression of the tumor-associated carbonic anhydrase IX J Kopacek, M Barathova, F Dequiedt, J Sepelakova, R Kettmann, ... Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1729 (1 …, 2005 | 94 | 2005 |
Upregulation of the genes encoding lysosomal hydrolases, a perforin-like protein, and peroxidases in the brains of mice affected with an experimental prion disease J Kopacek, S Sakaguchi, K Shigematsu, N Nishida, R Atarashi, ... Journal of virology 74 (1), 411-417, 2000 | 85 | 2000 |
Hypoxia-induced expression of carbonic anhydrase 9 is dependent on the unfolded protein response T van den Beucken, M Koritzinsky, H Niessen, L Dubois, K Savelkouls, ... Journal of Biological Chemistry 284 (36), 24204-24212, 2009 | 82 | 2009 |
Carbonic anhydrase inhibitors and the management of cancer S Pastorekova, J Kopacek, J Pastorek Current topics in medicinal chemistry 7 (9), 865-878, 2007 | 79 | 2007 |
Suppression of carbonic anhydrase IX leads to aberrant focal adhesion and decreased invasion of tumor cells P Radvak, M Repic, E Svastova, M Takacova, L Csaderova, H Strnad, ... Oncology reports 29 (3), 1147-1153, 2013 | 65 | 2013 |
Hypoxia upregulates expression of human endosialin gene via hypoxia-inducible factor 2 A Ohradanova, K Gradin, M Barathova, M Zatovicova, T Holotnakova, ... British journal of cancer 99 (8), 1348-1356, 2008 | 65 | 2008 |
CAIX regulates invadopodia formation through both a pH-dependent mechanism and interplay with actin regulatory proteins M Debreova, L Csaderova, M Burikova, L Lukacikova, I Kajanova, ... International journal of molecular sciences 20 (11), 2745, 2019 | 57 | 2019 |
PrP fragment 106-126 is toxic to cerebral endothelial cells expressing PrPC MA Deli, S Sakaguchi, R Nakaoke, CS Ábrahám, H Takahata, J Kopacek, ... Neuroreport 11 (17), 3931-3901, 2000 | 53 | 2000 |
Inhibitory effect of DIDS, NPPB, and phloretin on intracellular chloride channels L Malekova, J Tomaskova, M Novakova, P Stefanik, J Kopacek, B Lakatos, ... Pflügers Archiv-European Journal of Physiology 455, 349-357, 2007 | 48 | 2007 |
Intact intracellular tail is critical for proper functioning of the tumor-associated, hypoxia-regulated carbonic anhydrase IX A Hulikova, M Zatovicova, E Svastova, P Ditte, R Brasseur, R Kettmann, ... FEBS letters 583 (22), 3563-3568, 2009 | 43 | 2009 |
Modulation of expression of the sigma receptors in the heart of rat and mouse in normal and pathological conditions M Nováková, V Bruderová, Z Sulová, J Kopacek, L Lacinová, ... General physiology and biophysics 26 (2), 110, 2007 | 40 | 2007 |