| Water networks can determine the affinity of ligand binding to proteins JF Darby, AP Hopkins, S Shimizu, SM Roberts, JA Brannigan, ... Journal of the American Chemical Society 141 (40), 15818-15826, 2019 | 115 | 2019 |
| Increase of enzyme activity through specific covalent modification with fragments JF Darby, M Atobe, JD Firth, P Bond, GJ Davies, P O'Brien, RE Hubbard Chemical science 8 (11), 7772-7779, 2017 | 44 | 2017 |
| Discovery of selective small‐molecule activators of a bacterial glycoside hydrolase JF Darby, J Landström, C Roth, Y He, GJ Davies, RE Hubbard Angewandte Chemie International Edition 53 (49), 13419-13423, 2014 | 43 | 2014 |
| Substrate engagement and catalytic mechanisms of N-acetylglucosaminyltransferase V JF Darby, AK Gilio, B Piniello, C Roth, E Blagova, RE Hubbard, C Rovira, ... ACS Catalysis 10 (15), 8590-8596, 2020 | 26 | 2020 |
| Solution structure of the SGTA dimerisation domain and investigation of its interactions with the ubiquitin-like domains of BAG6 and UBL4A JF Darby, EM Krysztofinska, PJ Simpson, AC Simon, P Leznicki, ... PloS one 9 (11), e113281, 2014 | 26 | 2014 |
| Peptide transport in Bacillus subtilis–structure and specificity in the extracellular solute binding proteins OppA and DppE AM Hughes, JF Darby, EJ Dodson, SJ Wilson, JP Turkenburg, ... Microbiology 168 (12), 001274, 2022 | 15 | 2022 |
| Solution structure of the Hop TPR2A domain and investigation of target druggability by NMR, biochemical and in silico approaches JF Darby, LR Vidler, PJ Simpson, B Al-Lazikani, SJ Matthews, SY Sharp, ... Scientific reports 10 (1), 16000, 2020 | 14 | 2020 |
| Many faces of a cancer-supporting protein JF Darby, P Workman Nature 478 (7369), 334-335, 2011 | 11 | 2011 |
| Fragment-derived modulators of an industrial β-glucosidase E Makraki, JF Darby, MG Carneiro, JD Firth, A Heyam, E Ab, P O'Brien, ... Biochemical Journal 477 (22), 4383-4395, 2020 | 3 | 2020 |
| Efficient overexpression and purification of severe acute respiratory syndrome coronavirus 2 nucleocapsid proteins in Escherichia coli EL Brudenell, MB Pohare, D Zafred, J Phipps, HR Hornsby, JF Darby, ... Biochemical Journal 481 (11), 669-682, 2024 | 2 | 2024 |
| Efficient overexpression and purification of SARS-CoV-2 Nucleocapsid proteins inEscherichia coli EL Brudenell, MB Pohare, D Zafred, J Phipps, HR Hornsby, J Darby, J Dai, ... | | 2024 |
| Computational design of developable therapeutic antibodies: efficient traversal of binder landscapes and rescue of escape mutations FA Dreyer, C Schneider, A Kovaltsuk, D Cutting, MJ Byrne, DA Nissley, ... bioRxiv, 2024.10. 03.616038, 2024 | | 2024 |
| Abstract B99: Targeting TPR cochaperones of the Hsp90 molecular chaperone complex for specific inhibition. JF Darby, L Vidler, PJ Simpson, S Sharp, C Prodromou, S Matthews, ... Molecular Cancer Therapeutics 10 (11_Supplement), B99-B99, 2011 | | 2011 |
Roderick HubbardUniversity of York and Vernalis (R&D) Ltd在 york.ac.uk 的电子邮件经过验证
