Restoring cystic fibrosis transmembrane conductance regulator function reduces airway bacteria and inflammation in people with cystic fibrosis and chronic lung infections KB Hisert, SL Heltshe, C Pope, P Jorth, X Wu, RM Edwards, M Radey, ... American journal of respiratory and critical care medicine 195 (12), 1617-1628, 2017 | 366 | 2017 |
Metatranscriptomics of the human oral microbiome during health and disease P Jorth, KH Turner, P Gumus, N Nizam, N Buduneli, M Whiteley MBio 5 (2), 10.1128/mbio. 01012-14, 2014 | 364 | 2014 |
Regional isolation drives bacterial diversification within cystic fibrosis lungs P Jorth, BJ Staudinger, X Wu, KB Hisert, H Hayden, J Garudathri, ... Cell host & microbe 18 (3), 307-319, 2015 | 325 | 2015 |
Bacterial fight-and-flight responses enhance virulence in a polymicrobial infection A Stacy, J Everett, P Jorth, U Trivedi, KP Rumbaugh, M Whiteley Proceedings of the National Academy of Sciences 111 (21), 7819-7824, 2014 | 195 | 2014 |
Next-Generation “-omics” Approaches Reveal a Massive Alteration of Host RNA Metabolism during Bacteriophage Infection of Pseudomonas aeruginosa A Chevallereau, BG Blasdel, J De Smet, M Monot, M Zimmermann, ... PLoS genetics 12 (7), e1006134, 2016 | 115 | 2016 |
The unrecognized threat of secondary bacterial infections with COVID-19 M Vaillancourt, P Jorth MBio 11 (4), 10.1128/mbio. 01806-20, 2020 | 113 | 2020 |
Evolved Aztreonam Resistance Is Multifactorial and Can Produce Hypervirulence in Pseudomonas aeruginosa P Jorth, K McLean, A Ratjen, PR Secor, GE Bautista, S Ravishankar, ... MBio 8 (5), 10.1128/mbio. 00517-17, 2017 | 84 | 2017 |
Direct lung sampling indicates that established pathogens dominate early infections in children with cystic fibrosis P Jorth, Z Ehsan, A Rezayat, E Caldwell, C Pope, JJ Brewington, ... Cell reports 27 (4), 1190-1204. e3, 2019 | 76 | 2019 |
An evolutionary link between natural transformation and CRISPR adaptive immunity P Jorth, M Whiteley MBio 3 (5), 10.1128/mbio. 00309-12, 2012 | 75 | 2012 |
Characterization of the Pseudomonas aeruginosa Transcriptional Response to Phenylalanine and Tyrosine GC Palmer, KL Palmer, PA Jorth, M Whiteley Journal of bacteriology 192 (11), 2722-2728, 2010 | 68 | 2010 |
Pharmacologic improvement of CFTR function rapidly decreases sputum pathogen density, but lung infections generally persist DP Nichols, SJ Morgan, M Skalland, AT Vo, JM Van Dalfsen, SBP Singh, ... The Journal of Clinical Investigation 133 (10), 2023 | 65 | 2023 |
Probing bacterial metabolism during infection using high-resolution transcriptomics P Jorth, U Trivedi, K Rumbaugh, M Whiteley Journal of bacteriology 195 (22), 4991-4998, 2013 | 62 | 2013 |
Characterization of Alanine Catabolism in Pseudomonas aeruginosa and Its Importance for Proliferation In Vivo ML Boulette, PJ Baynham, PA Jorth, I Kukavica-Ibrulj, A Longoria, ... Journal of bacteriology 191 (20), 6329-6334, 2009 | 59 | 2009 |
Identification of immunologic and pathologic parameters of death versus survival in respiratory tularemia D Chiavolini, J Alroy, CA King, P Jorth, S Weir, G Madico, JR Murphy, ... Infection and immunity 76 (2), 486-496, 2008 | 56 | 2008 |
The role of two Pseudomonas aeruginosa anthranilate synthases in tryptophan and quorum signal production GC Palmer, PA Jorth, M Whiteley Microbiology 159 (Pt_5), 959-969, 2013 | 53 | 2013 |
Microbial community composition impacts pathogen iron availability during polymicrobial infection A Stacy, N Abraham, P Jorth, M Whiteley PLoS Pathogens 12 (12), e1006084, 2016 | 42 | 2016 |
Pseudomonas aeruginosa mexR and mexEF Antibiotic Efflux Pump Variants Exhibit Increased Virulence M Vaillancourt, SP Limsuwannarot, C Bresee, R Poopalarajah, P Jorth Antibiotics 10 (10), 1164, 2021 | 28 | 2021 |
Quantitative visualization of gene expression in mucoid and nonmucoid Pseudomonas aeruginosa aggregates reveals localized peak expression of alginate in the hypoxic zone P Jorth, MA Spero, J Livingston, DK Newman MBio 10 (6), 10.1128/mbio. 02622-19, 2019 | 25 | 2019 |
Characterization of a Novel Riboswitch-Regulated Lysine Transporter in Aggregatibacter actinomycetemcomitans P Jorth, M Whiteley Journal of bacteriology 192 (23), 6240-6250, 2010 | 25 | 2010 |
Metatranscriptomics of the human oral microbiome during health and disease. mBio 5 (2): e01012-14 P Jorth, KH Turner, P Gumus, N Nizam, N Buduneli, M Whiteley JAB-R, 2014 | 22 | 2014 |