关注
Yuan-Hung Lo
Yuan-Hung Lo
University of Texas MD Anderson Cancer Center
在 mdanderson.org 的电子邮件经过验证
标题
引用次数
引用次数
年份
Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration
CA Lindemans, M Calafiore, AM Mertelsmann, MH O’connor, JA Dudakov, ...
Nature 528 (7583), 560-564, 2015
10052015
CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities
K Han, SE Pierce, A Li, K Spees, GR Anderson, JA Seoane, YH Lo, ...
Nature 580 (7801), 136-141, 2020
2402020
The intestinal stem cell niche: homeostasis and adaptations
AJM Santos, YH Lo, AT Mah, CJ Kuo
Trends in cell biology 28 (12), 1062-1078, 2018
2232018
An expanded universe of cancer targets
WC Hahn, JS Bader, TP Braun, A Califano, PA Clemons, BJ Druker, ...
Cell 184 (5), 1142-1155, 2021
1552021
Applications of organoids for cancer biology and precision medicine
YH Lo, K Karlsson, CJ Kuo
Nature Cancer 1 (8), 761-773, 2020
1172020
T cell–derived interferon-γ programs stem cell death in immune-mediated intestinal damage
S Takashima, ML Martin, SA Jansen, Y Fu, J Bos, D Chandra, ...
Science Immunology 4 (42), eaay8556, 2019
1092019
Targeting tyrosine phosphorylation of PCNA inhibits prostate cancer growth
H Zhao, YH Lo, L Ma, SE Waltz, JK Gray, MC Hung, SC Wang
Molecular cancer therapeutics 10 (1), 29-36, 2011
1082011
A CRISPR/Cas9-engineered ARID1A-deficient human gastric cancer organoid model reveals essential and nonessential modes of oncogenic transformation
YH Lo, KS Kolahi, Y Du, CY Chang, A Krokhotin, A Nair, WD Sobba, ...
Cancer Discovery 11 (6), 1562-1581, 2021
1042021
Transcriptional regulation by ATOH1 and its target SPDEF in the intestine
YH Lo, E Chung, Z Li, YW Wan, MM Mahe, MS Chen, TK Noah, KN Bell, ...
Cellular and Molecular Gastroenterology and Hepatology 3 (1), 51-71, 2017
832017
Sox4 promotes Atoh1-independent intestinal secretory differentiation toward tuft and enteroendocrine fates
AD Gracz, LA Samsa, MJ Fordham, DC Trotier, B Zwarycz, YH Lo, K Bao, ...
Gastroenterology 155 (5), 1508-1523. e10, 2018
782018
Activated STAT5 confers resistance to intestinal injury by increasing intestinal stem cell proliferation and regeneration
S Gilbert, H Nivarthi, CN Mayhew, YH Lo, TK Noah, J Vallance, T Rülicke, ...
Stem cell reports 4 (2), 209-225, 2015
722015
Interaction of proliferation cell nuclear antigen (PCNA) with c-Abl in cell proliferation and response to DNA damages in breast cancer
H Zhao, PC Ho, YH Lo, A Espejo, MT Bedford, MC Hung, SC Wang
PLoS One 7 (1), e29416, 2012
682012
SPDEF functions as a colorectal tumor suppressor by inhibiting β-catenin activity
TK Noah, YH Lo, A Price, G Chen, E King, MK Washington, BJ Aronow, ...
Gastroenterology 144 (5), 1012-1023. e6, 2013
672013
The Ron receptor tyrosine kinase activates c-Abl to promote cell proliferation through tyrosine phosphorylation of PCNA in breast cancer
H Zhao, MS Chen, YH Lo, SE Waltz, J Wang, PC Ho, J Vasiliauskas, ...
Oncogene 33 (11), 1429-1437, 2014
652014
Epithelial WNT ligands are essential drivers of intestinal stem cell activation
WY Zou, SE Blutt, XL Zeng, MS Chen, YH Lo, D Castillo-Azofeifa, ...
Cell reports 22 (4), 1003-1015, 2018
622018
SPDEF induces quiescence of colorectal cancer cells by changing the transcriptional targets of β-catenin
YH Lo, TK Noah, MS Chen, W Zou, E Borras, E Vilar, NF Shroyer
Gastroenterology 153 (1), 205-218. e8, 2017
442017
Growth Factor–Independent 1 Is a Tumor Suppressor Gene in Colorectal Cancer
MS Chen, YH Lo, X Chen, CS Williams, JM Donnelly, ZK Criss, S Patel, ...
Molecular Cancer Research 17 (3), 697-708, 2019
422019
Deterministic evolution and stringent selection during preneoplasia
CC Kasper Karlsson, Moritz J Przybilla, Eran Kotler, Aziz Khan, Hang Xu ...
Nature 618 (7964), 383-393, 2023
38*2023
The ErbB3 receptor tyrosine kinase negatively regulates Paneth cells by PI3K-dependent suppression of Atoh1
D Almohazey, YH Lo, CV Vossler, AJ Simmons, JJ Hsieh, EB Bucar, ...
Cell Death & Differentiation 24 (5), 855-865, 2017
372017
Epidermal growth factor receptor protects proliferating cell nuclear antigen from cullin 4A protein-mediated proteolysis
YH Lo, PC Ho, SC Wang
Journal of Biological Chemistry 287 (32), 27148-27157, 2012
322012
系统目前无法执行此操作,请稍后再试。
文章 1–20