关注
Rujin Cheng
Rujin Cheng
NGM Biopharmaceuticals Inc.
在 ngmbio.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Genetically encoding photocaged quinone methide to multitarget protein residues covalently in vivo
J Liu, S Li, NA Aslam, F Zheng, B Yang, R Cheng, N Wang, S Rozovsky, ...
Journal of the American Chemical Society 141 (24), 9458-9462, 2019
632019
A Genetically Encoded Fluorosulfonyloxybenzoyl-l-lysine for Expansive Covalent Bonding of Proteins via SuFEx Chemistry
J Liu, L Cao, PC Klauser, R Cheng, VY Berdan, W Sun, N Wang, ...
Journal of the American Chemical Society 143 (27), 10341-10351, 2021
612021
Site-specific incorporation of selenocysteine using an expanded genetic code and palladium-mediated chemical deprotection
J Liu, F Zheng, R Cheng, S Li, S Rozovsky, Q Wang, L Wang
Journal of the American Chemical Society 140 (28), 8807-8816, 2018
492018
Photocaged quinone methide crosslinkers for light‐controlled chemical crosslinking of protein–protein and protein–DNA complexes
J Liu, L Cai, W Sun, R Cheng, N Wang, L Jin, S Rozovsky, IB Seiple, ...
Angewandte Chemie International Edition 58 (52), 18839-18843, 2019
332019
Synthesis and semisynthesis of selenopeptides and selenoproteins
J Liu, R Cheng, S Rozovsky
Current opinion in chemical biology 46, 41-47, 2018
312018
Genetically encoded quinone methides enabling rapid, site-specific, and photocontrolled protein modification with amine reagents
J Liu, R Cheng, N Van Eps, N Wang, T Morizumi, WL Ou, PC Klauser, ...
Journal of the American Chemical Society 142 (40), 17057-17068, 2020
302020
Building and Breaking Bonds via a Compact S‐Propargyl‐Cysteine to Chemically Control Enzymes and Modify Proteins
J Liu, R Cheng, H Wu, S Li, PG Wang, WF DeGrado, S Rozovsky, L Wang
Angewandte Chemie 130 (39), 12884-12888, 2018
112018
Selenoprotein S: A versatile disordered protein
F Ghelichkhani, FA Gonzalez, MA Kapitonova, S Schaefer-Ramadan, ...
Archives of biochemistry and biophysics 731, 109427, 2022
102022
A target discovery pipeline identified ILT3 as a target for immunotherapy of multiple myeloma
F Di Meo, A Iyer, K Akama, R Cheng, C Yu, A Cesarano, N Kurihara, ...
Cell Reports Medicine 4 (7), 2023
82023
Methods| Re-engineering the site-specific Incorporation of selenocysteine into proteins
R Cheng, J Liu, L Wang, MB Forstner, S Rozovsky
Elsevier, 2021
52021
Angew. Chem. Int. Ed. 2019, 58, 18839-18843
J Liu, L Cai, W Sun, R Cheng, N Wang, L Jin, S Rozovsky, IB Seiple, ...
Angew. Chem 131, 19015-19019, 2019
52019
A novel Bi-specific T-cell engager targeting ILT3 is potently effective in multiple myeloma
F Di Meo, A Iyer, K Akama, C Yu, R Cheng, A Cesarano, S Marino, ...
Blood 140 (Supplement 1), 671-672, 2022
12022
Preclinical characterization of NGM936, a novel bispecific T cell engager targeting ILT3 for the treatment of acute myeloid leukemia with monocytic differentiation
VY Lin, A Iyer, K Akama, R Cheng, H Yang, J Aguayo, B Li, AK Kutach, ...
Blood 140 (Supplement 1), 9063-4, 2022
12022
Applying selenocysteine-mediated expressed protein ligation to prepare the membrane enzyme selenoprotein S
R Cheng, J Liu, V Daithankar, S Rozovsky
Methods in enzymology 662, 159-185, 2022
12022
ILT3 and CD33 Binding Agents And Methods of Use Thereof
K Akama, R Cheng, A Iyer, VY Lin, LB Rivera, JM Roda, J Tang, H Yang
WO Patent WO2023192850A1, 2023
2023
ACUTE MYELOID LEUKEMIAS: INVESTIGATIONAL THERAPIES, EXCLUDING TRANSPLANTATION AND CELLULAR IMMUNOTHERAPIES
VY Lin, A Iyer, K Akama, R Cheng, H Yang, J Aguayo, B Li, AK Kutach, ...
BLOOD 140, 9063-9064, 2022
2022
Multimerization of Binding Molecules Having An Antibody Constant Region Variant
R Cheng, B Fan, S Hansen
AU Patent AU2022266780A1, 2022
2022
Multimerization of Binding Molecules Having An Antibody Constant Region Variant
R Cheng, B Fan, S Hansen
CA Patent CA3216755A1, 2022
2022
Multimerization of Binding Molecules Having An Antibody Constant Region Variant
R Cheng, B Fan, S Hansen
WO Patent WO2022232246A1, 2022
2022
The Unconventional Self-Cleavage of Selenoprotein K
R Cheng, J Liu, MB Forstner, G Woodward, E Heppard, PR Hoffmann, ...
bioRxiv, 2021.05. 15.444318, 2021
2021
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