Executioner caspases and CAD are essential for mutagenesis induced by TRAIL or vincristine MA Miles, CJ Hawkins Cell death & disease 8 (10), e3062-e3062, 2017 | 38 | 2017 |
Old and novel functions of caspase-2 MA Miles, T Kitevska-Ilioski, CJ Hawkins International review of cell and molecular biology 332, 155-212, 2017 | 38 | 2017 |
Plexin B2 is a regulator of monocyte apoptotic cell disassembly GK Atkin-Smith, MA Miles, R Tixeira, FT Lay, M Duan, CJ Hawkins, ... Cell Reports 29 (7), 1821-1831. e3, 2019 | 34 | 2019 |
IAP antagonists sensitize murine osteosarcoma cells to killing by TNFα TM Shekhar, MA Miles, A Gupte, S Taylor, B Tascone, CR Walkley, ... Oncotarget 7 (23), 33866, 2016 | 24 | 2016 |
The proteasome inhibitor ixazomib inhibits the formation and growth of pulmonary and abdominal osteosarcoma metastases in mice MA Harris, MA Miles, TM Shekhar, C Cerra, SR Georgy, SD Ryan, ... Cancers 12 (5), 1207, 2020 | 20 | 2020 |
CrmA orthologs from diverse poxviruses potently inhibit caspases-1 and-8, yet cleavage site mutagenesis frequently produces caspase-1-specific variants DT Bloomer, T Kitevska-Ilioski, D Pantaki-Eimany, Y Ji, MA Miles, B Heras, ... Biochemical Journal 476 (9), 1335-1357, 2019 | 20 | 2019 |
Glycolysis and the pentose phosphate pathway promote LPS-induced NOX2 oxidase-and IFN-β-Dependent inflammation in macrophages JR Erlich, EE To, R Luong, F Liong, S Liong, O Oseghale, MA Miles, ... Antioxidants 11 (8), 1488, 2022 | 19 | 2022 |
Transient NK cell depletion facilitates pulmonary osteosarcoma metastases after intravenous inoculation in athymic mice MA Harris, BBM Hons, TM Shekhar, LA Coupland, MA Miles, CJ Hawkins Journal of Adolescent and Young Adult Oncology 9 (6), 667-671, 2020 | 13 | 2020 |
Inhibition of Bcl-2 or IAP proteins does not provoke mutations in surviving cells TM Shekhar, MM Green, DM Rayner, MA Miles, SM Cutts, CJ Hawkins Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 777, 23-32, 2015 | 13 | 2015 |
Proteasome inhibitors trigger mutations via activation of caspases and CAD, but mutagenesis provoked by the HDAC inhibitors vorinostat and romidepsin is caspase/CAD-independent MA Miles, MA Harris, CJ Hawkins Apoptosis 24, 404-413, 2019 | 10 | 2019 |
Mutagenic assessment of chemotherapy and Smac mimetic drugs in cells with defective DNA damage response pathways MA Miles, CJ Hawkins Scientific reports 8 (1), 14421, 2018 | 10 | 2018 |
Mutagenic consequences of sublethal cell death signaling CJ Hawkins, MA Miles International Journal of Molecular Sciences 22 (11), 6144, 2021 | 9 | 2021 |
TRAIL causes deletions at the HPRT and TK1 loci of clonogenically competent cells MA Miles, TM Shekhar, NE Hall, CJ Hawkins Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 787, 15-31, 2016 | 8 | 2016 |
Smac mimetics can provoke lytic cell death that is neither apoptotic nor necroptotic MA Miles, S Caruso, AA Baxter, IKH Poon, CJ Hawkins Apoptosis 25, 500-518, 2020 | 7 | 2020 |
The smac mimetic LCL161 targets established pulmonary osteosarcoma metastases in mice MA Harris, TM Shekhar, MA Miles, C Cerra, CJ Hawkins Clinical & Experimental Metastasis 38 (5), 441-449, 2021 | 6 | 2021 |
Executioner caspases and CAD are essential for mutagenesis induced by TRAIL or vincristine. Cell Death Dis 8 (10): e3062 MA Miles, CJ Hawkins | 6 | 2017 |
Tetrazolium reduction assays under-report cell death provoked by clinically relevant concentrations of proteasome inhibitors MA Harris, CJ Hawkins, MA Miles Molecular biology reports 47 (6), 4849-4856, 2020 | 5 | 2020 |
IAP antagonists sensitize murine osteosarcoma cells to killing by TNFα. Oncotarget 7 (23): 33866–33886 TM Shekhar, MA Miles, A Gupte, S Taylor, B Tascone, CR Walkley, ... | 5 | 2016 |
Influenza A virus elicits peri-vascular adipose tissue inflammation and vascular dysfunction of the aorta in pregnant mice O Oseghale, S Liong, M Coward-Smith, EE To, JR Erlich, R Luong, ... PLoS Pathogens 18 (8), e1010703, 2022 | 4 | 2022 |
Therapeutic targeting of endosome and mitochondrial reactive oxygen species protects mice from influenza virus morbidity EE To, JR Erlich, F Liong, S Liong, R Luong, O Oseghale, MA Miles, ... Frontiers in Pharmacology 13, 870156, 2022 | 3 | 2022 |