Massively parallel de novo protein design for targeted therapeutics A Chevalier, DA Silva, GJ Rocklin, DR Hicks, R Vergara, P Murapa, ... Nature 550 (7674), 74-79, 2017 | 448 | 2017 |
Accurate de novo design of hyperstable constrained peptides G Bhardwaj, VK Mulligan, CD Bahl, JM Gilmore, PJ Harvey, O Cheneval, ... Nature 538 (7625), 329-335, 2016 | 415 | 2016 |
Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome AL Kennedy, KC Myers, J Bowman, CJ Gibson, ND Camarda, E Furutani, ... Nature Communications 12 (1), 1334, 2021 | 121 | 2021 |
Pseudomonas aeruginosa sabotages the generation of host proresolving lipid mediators BA Flitter, KL Hvorecny, E Ono, T Eddens, J Yang, DH Kwak, CD Bahl, ... Proceedings of the national academy of sciences 114 (1), 136-141, 2017 | 78 | 2017 |
Discovery and engineering of enhanced SUMO protease enzymes YTK Lau, V Baytshtok, TA Howard, BM Fiala, JLM Johnson, LP Carter, ... Journal of Biological Chemistry 293 (34), 13224-13233, 2018 | 60 | 2018 |
Screening, large-scale production and structure-based classification of cystine-dense peptides CE Correnti, MM Gewe, C Mehlin, AD Bandaranayake, WA Johnsen, ... Nature structural & molecular biology 25 (3), 270-278, 2018 | 58 | 2018 |
Crystal structure of the cystic fibrosis transmembrane conductance regulator inhibitory factor Cif reveals novel active-site features of an epoxide hydrolase virulence factor CD Bahl, C Morisseau, JM Bomberger, BA Stanton, BD Hammock, ... Journal of bacteriology 192 (7), 1785-1795, 2010 | 48 | 2010 |
Stereochemical determinants of C-terminal specificity in PDZ peptide-binding domains: a novel contribution of the carboxylate-binding loop JF Amacher, PR Cushing, CD Bahl, T Beck, DR Madden Journal of Biological Chemistry 288 (7), 5114-5126, 2013 | 39 | 2013 |
Pseudomonas aeruginosa Cif defines a distinct class of α/β epoxide hydrolases utilizing a His/Tyr ring-opening pair C D Bahl, D R Madden Protein and peptide letters 19 (2), 186-193, 2012 | 30 | 2012 |
Signature motifs identify an Acinetobacter Cif virulence factor with epoxide hydrolase activity CD Bahl, KL Hvorecny, AA Bridges, AE Ballok, JM Bomberger, KC Cady, ... Journal of Biological Chemistry 289 (11), 7460-7469, 2014 | 27 | 2014 |
An epoxide hydrolase secreted by Pseudomonas aeruginosa decreases mucociliary transport and hinders bacterial clearance from the lung KL Hvorecny, E Dolben, S Moreau-Marquis, TH Hampton, TB Shabaneh, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 314 (1 …, 2018 | 23 | 2018 |
Inhibiting an epoxide hydrolase virulence factor from Pseudomonas aeruginosa protects CFTR CD Bahl, KL Hvorecny, JM Bomberger, BA Stanton, BD Hammock, ... Angewandte Chemie International Edition 54 (34), 9881-9885, 2015 | 22 | 2015 |
Epoxide-Mediated CifR Repression of cif Gene Expression Utilizes Two Binding Sites in Pseudomonas aeruginosa AE Ballok, CD Bahl, EL Dolben, AK Lindsay, JD St. Laurent, DA Hogan, ... Journal of bacteriology 194 (19), 5315-5324, 2012 | 22 | 2012 |
Purification, crystallization and preliminary X-ray diffraction analysis of Cif, a virulence factor secreted by Pseudomonas aeruginosa CD Bahl, DP MacEachran, GA O'Toole, DR Madden Acta Crystallographica Section F: Structural Biology and Crystallization …, 2010 | 22 | 2010 |
Growing Glycans in Rosetta: Accurate de novo glycan modeling, density fitting, and rational sequon design J Adolf-Bryfogle, JW Labonte, JC Kraft, M Shapovalov, S Raemisch, ... PLoS computational biology 20 (6), e1011895, 2024 | 18 | 2024 |
Active-site flexibility and substrate specificity in a bacterial virulence factor: crystallographic snapshots of an epoxide hydrolase KL Hvorecny, CD Bahl, S Kitamura, KSS Lee, BD Hammock, C Morisseau, ... Structure 25 (5), 697-707. e4, 2017 | 17 | 2017 |
Visualizing the mechanism of epoxide hydrolysis by the bacterial virulence enzyme Cif CD Bahl, KL Hvorecny, C Morisseau, SA Gerber, DR Madden Biochemistry 55 (5), 788-797, 2016 | 17 | 2016 |
Ensuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarks J Koehler Leman, S Lyskov, SM Lewis, J Adolf-Bryfogle, RF Alford, ... Nature communications 12 (1), 6947, 2021 | 16 | 2021 |
Integration of the Rosetta suite with the python software stack via reproducible packaging and core programming interfaces for distributed simulation AS Ford, BD Weitzner, CD Bahl Protein Science 29 (1), 43-51, 2020 | 16 | 2020 |
Two common structural motifs for TCR recognition by staphylococcal enterotoxins KEJ Rödström, P Regenthal, C Bahl, A Ford, D Baker, ... Scientific Reports 6 (1), 25796, 2016 | 16 | 2016 |