| Structural mechanism for STI-571 inhibition of abelson tyrosine kinase T Schindler, W Bornmann, P Pellicena, WT Miller, B Clarkson, J Kuriyan Science 289 (5486), 1938-1942, 2000 | 2472 | 2000 |
| Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571) B Nagar, WG Bornmann, P Pellicena, T Schindler, DR Veach, WT Miller, ... Cancer research 62 (15), 4236-4243, 2002 | 1320 | 2002 |
| The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans N King, MJ Westbrook, SL Young, A Kuo, M Abedin, J Chapman, ... Nature 451 (7180), 783-788, 2008 | 1241 | 2008 |
| Activation of the Sire-family tyrosine kinase Hck by SH3 domain displacement I Moarefi, M LaFevre-Bernt, F Sicheri, M Huse, CH Lee, J Kuriyan, ... Nature 385 (6617), 650-653, 1997 | 798 | 1997 |
| Progesterone receptor contains a proline-rich motif that directly interacts with SH3 domains and activates c-Src family tyrosine kinases V Boonyaratanakornkit, MP Scott, V Ribon, L Sherman, SM Anderson, ... Molecular cell 8 (2), 269-280, 2001 | 738 | 2001 |
| Receptor tyrosine kinases: mechanisms of activation and signaling SR Hubbard, WT Miller Current opinion in cell biology 19 (2), 117-123, 2007 | 683 | 2007 |
| Structure and autoregulation of the insulin-like growth factor 1 receptor kinase S Favelyukis, JH Till, SR Hubbard, WT Miller Nature structural biology 8 (12), 1058-1063, 2001 | 447 | 2001 |
| A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases H Chen, J Ma, W Li, AV Eliseenkova, C Xu, TA Neubert, WT Miller, ... Molecular cell 27 (5), 717-730, 2007 | 311 | 2007 |
| The protist, Monosiga brevicollis, has a tyrosine kinase signaling network more elaborate and diverse than found in any known metazoan G Manning, SL Young, WT Miller, Y Zhai Proceedings of the National Academy of Sciences 105 (28), 9674-9679, 2008 | 214 | 2008 |
| Improving SH3 domain ligand selectivity using a non-natural scaffold JT Nguyen, M Porter, M Amoui, WT Miller, RN Zuckermann, WA Lim Chemistry & biology 7 (7), 463-473, 2000 | 186 | 2000 |
| Reciprocal regulation of Hck activity by phosphorylation of Tyr527 and Tyr416: effect of introducing a high affinity intramolecular SH2 ligand M Porter, T Schindler, J Kuriyan, WT Miller Journal of Biological Chemistry 275 (4), 2721-2726, 2000 | 151 | 2000 |
| Processive phosphorylation of p130Cas by Src depends on SH3-polyproline interactions P Pellicena, WT Miller Journal of Biological Chemistry 276 (30), 28190-28196, 2001 | 142 | 2001 |
| Brk is coamplified with ErbB2 to promote proliferation in breast cancer B Xiang, K Chatti, H Qiu, B Lakshmi, A Krasnitz, J Hicks, M Yu, WT Miller, ... Proceedings of the National Academy of Sciences 105 (34), 12463-12468, 2008 | 137 | 2008 |
| Intramolecular regulatory interactions in the Src family kinase Hck probed by mutagenesis of a conserved tryptophan residue M LaFevre-Bernt, F Sicheri, A Pico, M Porter, J Kuriyan, WT Miller Journal of Biological Chemistry 273 (48), 32129-32134, 1998 | 128 | 1998 |
| Processive phosphorylation: mechanism and biological importance P Patwardhan, WT Miller Cellular signalling 19 (11), 2218-2226, 2007 | 122 | 2007 |
| Regulation of sprouty stability by Mnk1-dependent phosphorylation J DaSilva, L Xu, HJ Kim, WT Miller, D Bar-Sagi Molecular and cellular biology 26 (5), 1898-1907, 2006 | 113 | 2006 |
| Identification of novel SH3 domain ligands for the Src family kinase Hck: Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1 MP Scott, F Zappacosta, EY Kim, RS Annan, WT Miller Journal of Biological Chemistry 277 (31), 28238-28246, 2002 | 107 | 2002 |
| Use of synthetic peptide libraries and phosphopeptide-selective mass spectrometry to probe protein kinase substrate specificity. JH Till, RS Annan, SA Carr, WT Miller Journal of Biological Chemistry 269 (10), 7423-7428, 1994 | 107 | 1994 |
| Small‐molecule inhibition and activation‐loop trans‐phosphorylation of the IGF1 receptor J Wu, W Li, BP Craddock, KW Foreman, MJ Mulvihill, Q Ji, WT Miller, ... The EMBO journal 27 (14), 1985-1994, 2008 | 105 | 2008 |
| Regulation of the nonreceptor tyrosine kinase Brk by autophosphorylation and by autoinhibition H Qiu, WT Miller Journal of Biological Chemistry 277 (37), 34634-34641, 2002 | 105 | 2002 |
