Glioma: experimental models and reality K Lenting, R Verhaak, M Ter Laan, P Wesseling, W Leenders Acta neuropathologica 133, 263-282, 2017 | 303 | 2017 |
Antiangiogenic therapy of cerebral melanoma metastases results in sustained tumor progression via vessel co-option WPJ Leenders, B Küsters, K Verrijp, C Maass, P Wesseling, ... Clinical Cancer Research 10 (18), 6222-6230, 2004 | 274 | 2004 |
Concerns about anti-angiogenic treatment in patients with glioblastoma multiforme JJC Verhoeff, O Van Tellingen, A Claes, LJA Stalpers, ME Van Linde, ... BMC cancer 9, 1-9, 2009 | 232 | 2009 |
Vessel co-option: how tumors obtain blood supply in the absence of sprouting angiogenesis WPJ Leenders, B Küsters, RMW de Waal Endothelium 9 (2), 83-87, 2002 | 207 | 2002 |
Vascular Endothelial Growth Factor-A165 Induces Progression of Melanoma Brain Metastases without Induction of Sprouting Angiogenesis B Küsters, WPJ Leenders, P Wesseling, D Smits, K Verrijp, DJ Ruiter, ... Cancer research 62 (2), 341-345, 2002 | 192 | 2002 |
The endogenous anti-angiogenic VEGF isoform, VEGF165b inhibits human tumour growth in mice ES Rennel, E Waine, H Guan, Y Schüler, W Leenders, J Woolard, ... British journal of cancer 98 (7), 1250-1257, 2008 | 177 | 2008 |
Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198 RJ Molenaar, D Botman, MA Smits, VV Hira, SA van Lith, J Stap, ... Cancer research 75 (22), 4790-4802, 2015 | 159 | 2015 |
Altered metabolic landscape in IDH‐mutant gliomas affects phospholipid, energy, and oxidative stress pathways F Fack, S Tardito, G Hochart, A Oudin, L Zheng, S Fritah, A Golebiewska, ... EMBO molecular medicine 9 (12), 1681-1695, 2017 | 138 | 2017 |
Endonexin II, present on human liver plasma membranes, is a specific binding protein of small hepatitis B virus (HBV) envelope protein K Hertogs, WPJ Leenders, E Depla, WCC De Bruin, L Meheus, ... Virology 197 (2), 549-557, 1993 | 132 | 1993 |
Vascular endothelial growth factor and semaphorin induce neuropilin-1 endocytosis via separate pathways A Salikhova, L Wang, AA Lanahan, M Liu, M Simons, WPJ Leenders, ... Circulation research 103 (6), e71-e79, 2008 | 131 | 2008 |
Antiangiogenic compounds interfere with chemotherapy of brain tumors due to vessel normalization A Claes, P Wesseling, J Jeuken, C Maass, A Heerschap, WPJ Leenders Molecular cancer therapeutics 7 (1), 71-78, 2008 | 127 | 2008 |
Robotic injection of zebrafish embryos for high-throughput screening in disease models HP Spaink, C Cui, MI Wiweger, HJ Jansen, WJ Veneman, R Marín-Juez, ... Methods 62 (3), 246-254, 2013 | 119 | 2013 |
PLEXIN‐D1, a novel plexin family member, is expressed in vascular endothelium and the central nervous system during mouse embryogenesis B Van Der Zwaag, AJ Hellemons, WPJ Leenders, JPH Burbach, ... Developmental dynamics: an official publication of the American Association …, 2002 | 119 | 2002 |
Differential effects of vascular endothelial growth factor A isoforms in a mouse brain metastasis model of human melanoma B Küsters, RMW de Waal, P Wesseling, K Verrijp, C Maass, ... Cancer research 63 (17), 5408-5413, 2003 | 105 | 2003 |
Hypoxia-mediated mechanisms associated with antiangiogenic treatment resistance in glioblastomas S Mahase, RN Rattenni, P Wesseling, W Leenders, C Baldotto, R Jain, ... The American journal of pathology 187 (5), 940-953, 2017 | 101 | 2017 |
IDH1 R132H mutation generates a distinct phospholipid metabolite profile in glioma M Esmaeili, BC Hamans, AC Navis, R van Horssen, TF Bathen, ... Cancer research 74 (17), 4898-4907, 2014 | 100 | 2014 |
p120-catenin-dependent collective brain infiltration by glioma cell networks PG Gritsenko, N Atlasy, CEJ Dieteren, AC Navis, JH Venhuizen, ... Nature cell biology 22 (1), 97-107, 2020 | 99 | 2020 |
Specific imaging of VEGF‐A expression with radiolabeled anti‐VEGF monoclonal antibody TH Stollman, MGW Scheer, WPJ Leenders, KCN Verrijp, AC Soede, ... International journal of cancer 122 (10), 2310-2314, 2008 | 97 | 2008 |
Phenotypic and genotypic characterization of orthotopic human glioma models and its relevance for the study of anti‐glioma therapy A Claes, J Schuuring, S Boots‐Sprenger, S Hendriks‐Cornelissen, ... Brain pathology 18 (3), 423-433, 2008 | 93 | 2008 |
Circulating tumour tissue fragments in patients with pulmonary metastasis of clear cell renal cell carcinoma G Kats‐Ugurlu, I Roodink, M de Weijert, D Tiemessen, C Maass, K Verrijp, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 2009 | 92 | 2009 |