| The structure of human 5-lipoxygenase NC Gilbert, SG Bartlett, MT Waight, DB Neau, WE Boeglin, AR Brash, ... Science 331 (6014), 217-219, 2011 | 473 | 2011 |
| Structural and mechanistic insights into 5-lipoxygenase inhibition by natural products NC Gilbert, J Gerstmeier, EE Schexnaydre, F Börner, U Garscha, ... Nature chemical biology 16 (7), 783-790, 2020 | 168 | 2020 |
| Conversion of human 5-lipoxygenase to a 15-lipoxygenase by a point mutation to mimic phosphorylation at Serine-663 NC Gilbert, Z Rui, DB Neau, MT Waight, SG Bartlett, WE Boeglin, ... The FASEB Journal 26 (8), 3222, 2012 | 162 | 2012 |
| The 1.85 Å Structure of an 8R-Lipoxygenase Suggests a General Model for Lipoxygenase Product Specificity DB Neau, NC Gilbert, SG Bartlett, W Boeglin, AR Brash, ME Newcomer Biochemistry 48 (33), 7906-7915, 2009 | 126 | 2009 |
| Structural basis of arrestin-3 activation and signaling Q Chen, NA Perry, SA Vishnivetskiy, S Berndt, NC Gilbert, Y Zhuo, ... Nature Communications 8 (1), 1427, 2017 | 113 | 2017 |
| Structure of a calcium-dependent 11R-lipoxygenase suggests a mechanism for Ca2+ regulation P Eek, R Järving, I Järving, NC Gilbert, ME Newcomer, N Samel Journal of Biological Chemistry 287 (26), 22377-22386, 2012 | 81 | 2012 |
| Location, location, location: compartmentalization of early events in leukotriene biosynthesis ME Newcomer, NC Gilbert Journal of Biological Chemistry 285 (33), 25109-25114, 2010 | 74 | 2010 |
| Untangling the web of 5-lipoxygenase-derived products from a molecular and structural perspective: the battle between pro-and anti-inflammatory lipid mediators NC Gilbert, ME Newcomer, O Werz Biochemical pharmacology 193, 114759, 2021 | 37 | 2021 |
| Anti-inflammatory celastrol promotes a switch from leukotriene biosynthesis to formation of specialized pro-resolving lipid mediators S Pace, K Zhang, PM Jordan, R Bilancia, W Wang, F Börner, ... Pharmacological research 167, 105556, 2021 | 25 | 2021 |
| Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2 WC Tsai, NC Gilbert, A Ohler, M Armstrong, S Perry, C Kalyanaraman, ... Bioorganic & medicinal chemistry 46, 116349, 2021 | 24 | 2021 |
| Improving protein crystal quality by selective removal of a Ca2+-dependent membrane-insertion loop DB Neau, NC Gilbert, SG Bartlett, A Dassey, ME Newcomer Acta Crystallographica Section F: Structural Biology and Crystallization …, 2007 | 20 | 2007 |
| Histidine switch controlling pH-dependent protein folding and DNA binding in a transcription factor at the core of synthetic network devices DK Deochand, IC Perera, RB Crochet, NC Gilbert, ME Newcomer, ... Molecular biosystems 12 (8), 2417-2426, 2016 | 19 | 2016 |
| A covalent linker allows for membrane targeting of an oxylipin biosynthetic complex NC Gilbert, M Niebuhr, H Tsuruta, T Bordelon, O Ridderbusch, A Dassey, ... Biochemistry 47 (40), 10665-10676, 2008 | 17 | 2008 |
| Allosteric activation of 15‐lipoxygenase‐1 by boswellic acid induces the lipid mediator class switch to promote resolution of inflammation F Börner, S Pace, PM Jordan, J Gerstmeier, M Gomez, A Rossi, ... Advanced Science 10 (6), 2205604, 2023 | 16 | 2023 |
| X-ray structure of chromium (III)-containing transferrin: First structure of a physiological Cr (III)-binding protein CM Petersen, KC Edwards, NC Gilbert, JB Vincent, MK Thompson Journal of Inorganic Biochemistry 210, 111101, 2020 | 10 | 2020 |
| Investigating membrane-binding properties of lipoxygenases using surface plasmon resonance DL Rohlik, E Patel, NC Gilbert, AR Offenbacher, BL Garcia Biochemical and Biophysical Research Communications 670, 47-54, 2023 | 9 | 2023 |
| Expression of an 8R-lipoxygenase from the coral Plexaura homomalla NC Gilbert, DB Neau, ME Newcomer Methods in enzymology 605, 33-49, 2018 | 9 | 2018 |
| Helical remodeling augments 5-lipoxygenase activity in the synthesis of proinflammatory mediators EM Gallegos, TD Reed, FA Mathes, NV Guevara, DB Neau, W Huang, ... Journal of Biological Chemistry 298 (9), 2022 | 8 | 2022 |
| Cannabidiol acts as molecular switch in innate immune cells to promote the biosynthesis of inflammation-resolving lipid mediators LK Peltner, L Gluthmann, F Börner, S Pace, RK Hoffstetter, C Kretzer, ... Cell Chemical Biology 30 (12), 1508-1524. e7, 2023 | 7 | 2023 |
| Characterization of the genomically encoded fosfomycin resistance enzyme from Mycobacterium abscessus S Travis, MR Shay, S Manabe, NC Gilbert, PA Frantom, MK Thompson Medchemcomm 10 (11), 1948-1957, 2019 | 5 | 2019 |
