Autophagy and neurodegeneration: pathogenic mechanisms and therapeutic opportunities FM Menzies, A Fleming, A Caricasole, CF Bento, SP Andrews, ... Neuron 93 (5), 1015-1034, 2017 | 1063 | 2017 |
The different autophagy degradation pathways and neurodegeneration A Fleming, M Bourdenx, M Fujimaki, C Karabiyik, GJ Krause, A Lopez, ... Neuron, 2022 | 204 | 2022 |
Autophagy impairment in Parkinson’s disease C Karabiyik, MJ Lee, DC Rubinsztein Essays in biochemistry 61 (6), 711-720, 2017 | 145 | 2017 |
Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing FH Siddiqi, FM Menzies, A Lopez, E Stamatakou, C Karabiyik, R Ureshino, ... Nature communications 10 (1), 1817, 2019 | 113 | 2019 |
Glucose starvation induces autophagy via ULK1-mediated activation of PIKfyve in an AMPK-dependent manner C Karabiyik, M Vicinanza, SM Son, DC Rubinsztein Developmental Cell 56 (13), 1961-1975. e5, 2021 | 53 | 2021 |
Autophagy in ageing and ageing-related neurodegenerative diseases C Karabiyik, RA Frake, SJ Park, M Pavel, DC Rubinsztein Ageing Neurodegener. Dis 1 (2), 2021 | 21 | 2021 |
mTORC2 Assembly Is Regulated by USP9X-Mediated Deubiquitination of RICTOR L Wrobel, FH Siddiqi, SM Hill, SM Son, C Karabiyik, H Kim, ... Cell Reports 33 (13), 108564, 2020 | 21 | 2020 |
Neuronal Rho GTPase Rac1 elimination confers neuroprotection in a mouse model of permanent ischemic stroke C Karabiyik, R Fernandes, FR Figueiredo, R Socodato, C Brakebusch, ... Brain Pathology 28 (4), 569-580, 2018 | 20 | 2018 |
Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance L Wrobel, SM Hill, A Djajadikerta, M Fernandez-Estevez, C Karabiyik, ... Nature Communications 13 (1), 4146, 2022 | 14 | 2022 |
Vinexin contributes to autophagic decline in brain ageing across species SJ Park, RA Frake, C Karabiyik, SM Son, FH Siddiqi, CF Bento, P Sterk, ... Cell Death & Differentiation 29 (5), 1055-1070, 2022 | 6 | 2022 |
AMPK-activated ULK1 phosphorylates PIKFYVE to drive formation of PtdIns5P-containing autophagosomes during glucose starvation C Karabiyik, DC Rubinsztein Autophagy 17 (11), 3877-3878, 2021 | 6 | 2021 |
Lysosome positioning and mTOR activity in Lowe syndrome C Karabiyik, SM Son, DC Rubinsztein EMBO reports 22 (7), e53232, 2021 | 2 | 2021 |
AMPK: the energy sensor that regulates autophagy and a potential therapeutic target for neurodegenerative diseases C Karabiyik, M Vicinanza, DC Rubinsztein Non-Canonical Autophagy, 9-39, 2021 | 1 | 2021 |
Protocol for determining the regulation of lipid kinases and changes in phospholipids in vitro C Karabiyik, DC Rubinsztein STAR protocols 2 (4), 100926, 2021 | | 2021 |
A study on non-canonical autophagy signalling C Karabiyik University of Cambridge, 2021 | | 2021 |