| Fundamental mechanisms of regulated cell death and implications for heart disease DP Del Re, D Amgalan, A Linkermann, Q Liu, RN Kitsis Physiological reviews 99 (4), 1765-1817, 2019 | 676 | 2019 |
| A small-molecule allosteric inhibitor of BAX protects against doxorubicin-induced cardiomyopathy D Amgalan, TP Garner, R Pekson, XF Jia, M Yanamandala, V Paulino, ... Nature cancer 1 (3), 315-328, 2020 | 94 | 2020 |
| Small-molecule allosteric inhibitors of BAX TP Garner, D Amgalan, DE Reyna, S Li, RN Kitsis, E Gavathiotis Nature chemical biology 15 (4), 322-330, 2019 | 81 | 2019 |
| Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis R Miao, C Jiang, WY Chang, H Zhang, J An, F Ho, P Chen, H Zhang, ... Immunity 56 (11), 2523-2541. e8, 2023 | 57 | 2023 |
| Grounding cardio-oncology in basic and clinical science J Moslehi, D Amgalan, RN Kitsis Circulation 136 (1), 3-5, 2017 | 35 | 2017 |
| SNAP23 regulates BAX-dependent adipocyte programmed cell death independently of canonical macroautophagy D Feng, D Amgalan, R Singh, J Wei, J Wen, TP Wei, TE McGraw, ... The Journal of Clinical Investigation 128 (9), 3941-3956, 2018 | 28 | 2018 |
| Death receptor signaling in the heart: cell survival, apoptosis, and necroptosis D Amgalan, Y Chen, RN Kitsis Circulation 136 (8), 743-746, 2017 | 23 | 2017 |
| Troponin release following brief myocardial ischemia: apoptosis versus necrosis D Amgalan, R Pekson, RN Kitsis Basic to Translational Science 2 (2), 118-121, 2017 | 23 | 2017 |
| A mouse model for the most common form of heart failure D Amgalan, RN Kitsis Nature 568 (7752), 324-325, 2019 | 20 | 2019 |
| An Akt3 splice variant lacking the serine 472 phosphorylation site promotes apoptosis and suppresses mammary tumorigenesis K Suyama, J Yao, H Liang, O Benard, OD Loudig, D Amgalan, ... Cancer research 78 (1), 103-114, 2018 | 17 | 2018 |
| Computational estimates of annular diameter reveal genetic determinants of mitral valve function and disease M Yu, C Tcheandjieu, A Georges, K Xiao, H Tejeda, C Dina, ... JCI insight 7 (3), 2022 | 12 | 2022 |
| ATG16L1 autophagy pathway regulates BAX protein levels and programmed cell death F Chen, D Amgalan, RN Kitsis, JE Pessin, D Feng Journal of Biological Chemistry 295 (44), 15045-15053, 2020 | 10 | 2020 |
| The impact of genomic variation on function (IGVF) consortium IGVF Consortium ArXiv, 2023 | 5 | 2023 |
| Genetic determinants of the interventricular septum are linked to ventricular septal defects and hypertrophic cardiomyopathy M Yu, AR Harper, M Aguirre, M Pittman, C Tcheandjieu, D Amgalan, ... Circulation: Genomic and Precision Medicine 16 (3), 207-215, 2023 | 3 | 2023 |
| Computational estimates of mitral annular diameter in systole and diastole cardiac cycle reveal novel genetic determinants of valve function and disease M Yu, C Tcheandjieu, A Georges, K Xiao, H Tejeda, C Dina, ... medRxiv, 2020.12. 02.20242206, 2020 | 3 | 2020 |
| Oligogenic Architecture of Rare Noncoding Variants Distinguishes 4 Congenital Heart Disease Phenotypes M Yu, M Aguirre, M Jia, K Gjoni, A Cordova-Palomera, C Munger, ... Circulation: Genomic and Precision Medicine 16 (3), 258-266, 2023 | 2 | 2023 |
| Small molecule BAX inhibitors and uses thereof E Gavathiotis, RN Kitsis, TP Garner, D Amgalan, L Kirshenbaum, F Kopp US Patent 11,938,128, 2024 | | 2024 |
| The Impact of Genomic Variation on Function (IGVF) Consortium I Consortium arXiv preprint arXiv:2307.13708, 2023 | | 2023 |
| Genetic determinants of interventricular septal anatomy and the risk of ventricular septal defects and hypertrophic cardiomyopathy M Yu, AR Harper, M Aguirre, M Pittman, C Tcheandjieu, D Amgalan, ... medRxiv, 2021.04. 19.21255650, 2021 | | 2021 |
| Small molecule bax inhibitors and uses thereof E Gavathiotis, RN KITSIS, TP GARNER, D AMGALAN, L KIRSHENBAUM, ... | | 2018 |
