Gene-expression profiling of bortezomib added to standard chemoimmunotherapy for diffuse large B-cell lymphoma (REMoDL-B): an open-label, randomised, phase 3 trial A Davies, TE Cummin, S Barrans, T Maishman, C Mamot, U Novak, ... The Lancet Oncology 20 (5), 649-662, 2019 | 263 | 2019 |
Molecular high-grade B-cell lymphoma: defining a poor-risk group that requires different approaches to therapy C Sha, S Barrans, F Cucco, MA Bentley, MA Care, T Cummin, H Kennedy, ... Journal of Clinical Oncology 37 (3), 202-212, 2019 | 238 | 2019 |
Depletion of RUNX1/ETO in t (8; 21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding A Ptasinska, SA Assi, D Mannari, SR James, D Williamson, J Dunne, ... Leukemia 26 (8), 1829-1841, 2012 | 206 | 2012 |
In vitro generation of long-lived human plasma cells M Cocco, S Stephenson, MA Care, D Newton, NA Barnes, A Davison, ... The Journal of Immunology 189 (12), 5773-5785, 2012 | 139 | 2012 |
Whole genome expression profiling based on paraffin embedded tissue can be used to classify diffuse large B‐cell lymphoma and predict clinical outcome SL Barrans, S Crouch, MA Care, L Worrillow, A Smith, R Patmore, ... British journal of haematology 159 (4), 441-453, 2012 | 110 | 2012 |
Distinct genetic changes reveal evolutionary history and heterogeneous molecular grade of DLBCL with MYC/BCL2 double-hit F Cucco, S Barrans, C Sha, A Clipson, S Crouch, R Dobson, Z Chen, ... Leukemia 34 (5), 1329-1341, 2020 | 93 | 2020 |
Biallelic mutations in IRF8 impair human NK cell maturation and function EM Mace, V Bigley, JT Gunesch, IK Chinn, LS Angelo, MA Care, ... The Journal of clinical investigation 127 (1), 306-320, 2017 | 91 | 2017 |
Biallelic interferon regulatory factor 8 mutation: A complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation V Bigley, S Maisuria, U Cytlak, L Jardine, MA Care, K Green, M Gunawan, ... Journal of Allergy and Clinical Immunology 141 (6), 2234-2248, 2018 | 82 | 2018 |
A microarray platform-independent classification tool for cell of origin class allows comparative analysis of gene expression in diffuse large B-cell lymphoma MA Care, S Barrans, L Worrillow, A Jack, DR Westhead, RM Tooze PloS one 8 (2), e55895, 2013 | 80 | 2013 |
Deleterious SNP prediction: be mindful of your training data! MA Care, CJ Needham, AJ Bulpitt, DR Westhead Bioinformatics 23 (6), 664-672, 2007 | 73 | 2007 |
An extended set of PRDM1/BLIMP1 target genes links binding motif type to dynamic repression GM Doody, MA Care, NJ Burgoyne, JR Bradford, M Bota, C Bonifer, ... Nucleic acids research 38 (16), 5336-5350, 2010 | 67 | 2010 |
Network analysis identifies proinflammatory plasma cell polarization for secretion of ISG15 in human autoimmunity MA Care, SJ Stephenson, NA Barnes, I Fan, A Zougman, YM El-Sherbiny, ... The Journal of Immunology 197 (4), 1447-1459, 2016 | 57 | 2016 |
SPIB and BATF provide alternate determinants of IRF4 occupancy in diffuse large B-cell lymphoma linked to disease heterogeneity MA Care, M Cocco, JP Laye, N Barnes, Y Huang, M Wang, S Barrans, ... Nucleic acids research 42 (12), 7591-7610, 2014 | 55 | 2014 |
A sequence‐anchored genetic linkage map for the moss, Physcomitrella patens Y Kamisugi, M Von Stackelberg, D Lang, M Care, R Reski, SA Rensing, ... The plant journal 56 (5), 855-866, 2008 | 51 | 2008 |
A prospective randomised trial of targeted therapy for diffuse large B-cell lymphoma (DLBCL) based upon real-time gene expression profiling: the Remodl-B study of the UK NCRI … AJ Davies, J Caddy, T Maishman, S Barrans, C Mamot, M Care, C Pocock, ... Blood 126 (23), 812, 2015 | 37 | 2015 |
Predicting the effect of missense mutations on protein function: analysis with Bayesian networks CJ Needham, JR Bradford, AJ Bulpitt, MA Care, DR Westhead BMC bioinformatics 7, 1-14, 2006 | 35 | 2006 |
Site-1 protease function is essential for the generation of antibody secreting cells and reprogramming for secretory activity M Al-Maskari, MA Care, E Robinson, M Cocco, RM Tooze, GM Doody Scientific reports 8 (1), 14338, 2018 | 34 | 2018 |
S1PR1 drives a feedforward signalling loop to regulate BATF3 and the transcriptional programme of Hodgkin lymphoma cells K Vrzalikova, M Ibrahim, M Vockerodt, T Perry, S Margielewska, L Lupino, ... Leukemia 32 (1), 214-223, 2018 | 33 | 2018 |
Parsimonious Gene Correlation Network Analysis (PGCNA): a tool to define modular gene co-expression for refined molecular stratification in cancer MA Care, DR Westhead, RM Tooze NPJ systems biology and applications 5 (1), 13, 2019 | 31 | 2019 |
Sphingosine-1-phosphate signalling drives an angiogenic transcriptional programme in diffuse large B cell lymphoma L Lupino, T Perry, S Margielewska, R Hollows, M Ibrahim, M Care, ... Leukemia 33 (12), 2884-2897, 2019 | 30 | 2019 |