| Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture LC Laurent, I Ulitsky, I Slavin, H Tran, A Schork, R Morey, C Lynch, ... Cell stem cell 8 (1), 106-118, 2011 | 1030 | 2011 |
| Regulation of gene expression by small molecules JM Gottesfeld, L Neely, JW Trauger, EE Baird, PB Dervan Nature 387 (6629), 202-205, 1997 | 657 | 1997 |
| Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia D Herman, K Jenssen, R Burnett, E Soragni, SL Perlman, JM Gottesfeld Nature chemical biology 2 (10), 551-558, 2006 | 513 | 2006 |
| Mitotic repression of the transcriptional machinery JM Gottesfeld, DJ Forbes Trends in biochemical sciences 22 (6), 197-202, 1997 | 470 | 1997 |
| Zinc finger protein derivatives and methods therefor CF Barbas III, JM Gottesfeld, PE Wright US Patent 6,140,466, 2000 | 427 | 2000 |
| Zinc finger protein derivatives and methods therefor CF Barbas III, JM Gottesfeld, PE Wright US Patent 6,242,568, 2001 | 404 | 2001 |
| Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands LA Dickinson, RJ Gulizia, JW Trauger, EE Baird, DE Mosier, JM Gottesfeld, ... Proceedings of the National Academy of Sciences 95 (22), 12890-12895, 1998 | 371 | 1998 |
| The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice EA Thomas, G Coppola, PA Desplats, B Tang, E Soragni, R Burnett, ... Proceedings of the National Academy of Sciences 105 (40), 15564-15569, 2008 | 339 | 2008 |
| Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis DM Hutt, D Herman, APC Rodrigues, S Noel, JM Pilewski, J Matteson, ... Nature chemical biology 6 (1), 25-33, 2010 | 285 | 2010 |
| HDAC inhibitors correct frataxin deficiency in a Friedreich ataxia mouse model M Rai, E Soragni, K Jenssen, R Burnett, D Herman, G Coppola, ... PloS one 3 (4), e1958, 2008 | 263 | 2008 |
| Partial purification of the template-active fraction of chromatin: a preliminary report JM Gottesfeld, WT Garrard, G Bagi, RF Wilson, J Bonner Proceedings of the National Academy of Sciences 71 (6), 2193-2197, 1974 | 254 | 1974 |
| Friedreich's ataxia induced pluripotent stem cells model intergenerational GAA⋅ TTC triplet repeat instability S Ku, E Soragni, E Campau, EA Thomas, G Altun, LC Laurent, JF Loring, ... Cell stem cell 7 (5), 631-637, 2010 | 241 | 2010 |
| Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I histone deacetylases CJ Chou, D Herman, JM Gottesfeld Journal of Biological Chemistry 283 (51), 35402-35409, 2008 | 239 | 2008 |
| Solution structure of the first three zinc fingers of TFIIIA bound to the cognate DNA sequence: determinants of affinity and sequence specificity DS Wuttke, MP Foster, DA Case, JM Gottesfeld, PE Wright Journal of molecular biology 273 (1), 183-206, 1997 | 235 | 1997 |
| Assembly of transcriptionally active 5S RNA gene chromatin in vitro J Gottesfeld, LS Bloomer Cell 28 (4), 781-791, 1982 | 209 | 1982 |
| Crystal structures of nucleosome core particles in complex with minor groove DNA-binding ligands RK Suto, RS Edayathumangalam, CL White, C Melander, JM Gottesfeld, ... Journal of molecular biology 326 (2), 371-380, 2003 | 205 | 2003 |
| Molecular basis for specific recognition of both RNA and DNA by a zinc finger protein KR Clemens, V Wolf, SJ McBryant, P Zhang, X Liao, PE Wright, ... Science 260 (5107), 530-533, 1993 | 185 | 1993 |
| Two new pimelic diphenylamide HDAC inhibitors induce sustained frataxin upregulation in cells from Friedreich's ataxia patients and in a mouse model M Rai, E Soragni, CJ Chou, G Barnes, S Jones, JR Rusche, JM Gottesfeld, ... PloS one 5 (1), e8825, 2010 | 174 | 2010 |
| Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of Huntington's disease H Jia, J Pallos, V Jacques, A Lau, B Tang, A Cooper, A Syed, J Purcell, ... Neurobiology of disease 46 (2), 351-361, 2012 | 173 | 2012 |
| Domain packing and dynamics in the DNA complex of the N-terminal zinc fingers of TFIIIA. MP Foster, DS Wuttke, I Radhakrishnan, DA Case, JM Gottesfeld, ... Nature structural biology 4 (8), 605-608, 1997 | 171 | 1997 |
