Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue JPJ Saeij, S Coller, JP Boyle, ME Jerome, MW White, JC Boothroyd Nature 445 (7125), 324-327, 2007 | 677 | 2007 |
Polymorphic secreted kinases are key virulence factors in toxoplasmosis JPJ Saeij, JP Boyle, S Coller, S Taylor, LD Sibley, ET Brooke-Powell, ... Science 314 (5806), 1780-1783, 2006 | 668 | 2006 |
Differences among the three major strains of Toxoplasma gondii and their specific interactions with the infected host JPJ Saeij, JP Boyle, JC Boothroyd Trends in parasitology 21 (10), 476-481, 2005 | 425 | 2005 |
Polymorphic family of injected pseudokinases is paramount in Toxoplasma virulence ML Reese, GM Zeiner, JPJ Saeij, JC Boothroyd, JP Boyle Proceedings of the National Academy of Sciences 108 (23), 9625-9630, 2011 | 293 | 2011 |
Local admixture of amplified and diversified secreted pathogenesis determinants shapes mosaic Toxoplasma gondii genomes H Lorenzi, A Khan, MS Behnke, S Namasivayam, LS Swapna, ... Nature communications 7 (1), 10147, 2016 | 272 | 2016 |
Bioluminescence Imaging of Toxoplasma gondii Infection in Living Mice Reveals Dramatic Differences between Strains JPJ Saeij, JP Boyle, ME Grigg, G Arrizabalaga, JC Boothroyd Infection and immunity 73 (2), 695-702, 2005 | 259 | 2005 |
Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii A Khan, S Taylor, C Su, AJ Mackey, J Boyle, R Cole, D Glover, K Tang, ... Nucleic acids research 33 (9), 2980-2992, 2005 | 239 | 2005 |
Using RNA interference to manipulate endogenous gene expression in Schistosoma mansoni sporocysts JP Boyle, XJ Wu, CB Shoemaker, TP Yoshino Molecular and biochemical parasitology 128 (2), 205-215, 2003 | 223 | 2003 |
Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole A Khaminets, JP Hunn, S Könen‐Waisman, YO Zhao, D Preukschat, ... Cellular microbiology 12 (7), 939-961, 2010 | 222 | 2010 |
Toxoplasma Effector MAF1 Mediates Recruitment of Host Mitochondria and Impacts the Host Response L Pernas, Y Adomako-Ankomah, AJ Shastri, SE Ewald, M Treeck, ... PLoS biology 12 (4), e1001845, 2014 | 200 | 2014 |
Just one cross appears capable of dramatically altering the population biology of a eukaryotic pathogen like Toxoplasma gondii JP Boyle, B Rajasekar, JPJ Saeij, JW Ajioka, M Berriman, I Paulsen, ... Proceedings of the National Academy of Sciences 103 (27), 10514-10519, 2006 | 159 | 2006 |
Description of the Transcriptomes of Immune Response-Activated Hemocytes from the Mosquito Vectors Aedes aegypti and Armigeres subalbatus LC Bartholomay, WL Cho, TA Rocheleau, JP Boyle, ET Beck, JF Fuchs, ... Infection and immunity 72 (7), 4114-4126, 2004 | 155 | 2004 |
Age‐associated mortality in immune challenged mosquitoes (Aedes aegypti) correlates with a decrease in haemocyte numbers JF Hillyer, SL Schmidt, JF Fuchs, JP Boyle, BM Christensen Cellular microbiology 7 (1), 39-51, 2005 | 137 | 2005 |
A three-dimensional culture system recapitulates placental syncytiotrophoblast development and microbial resistance CA McConkey, E Delorme-Axford, CA Nickerson, KS Kim, Y Sadovsky, ... Science advances 2 (3), e1501462, 2016 | 121 | 2016 |
Human trophoblasts confer resistance to viruses implicated in perinatal infection A Bayer, E Delorme-Axford, C Sleigher, TK Frey, DW Trobaugh, ... American journal of obstetrics and gynecology 212 (1), 71. e1-71. e8, 2015 | 115 | 2015 |
Integrated Bioinformatic and Targeted Deletion Analyses of the SRS Gene Superfamily Identify SRS29C as a Negative Regulator of Toxoplasma Virulence JD Wasmuth, V Pszenny, S Haile, EM Jansen, AT Gast, A Sher, JP Boyle, ... MBio 3 (6), 10.1128/mbio. 00321-12, 2012 | 91 | 2012 |
Toxoplasma gondii: inconsistent dissemination patterns following oral infection in mice JP Boyle, JPJ Saeij, JC Boothroyd Experimental parasitology 116 (3), 302-305, 2007 | 77 | 2007 |
Human Placental Syncytiotrophoblasts Restrict Toxoplasma gondii Attachment and Replication and Respond to Infection by Producing Immunomodulatory … SE Ander, EN Rudzki, N Arora, Y Sadovsky, CB Coyne, JP Boyle MBio 9 (1), 10.1128/mbio. 01678-17, 2018 | 68 | 2018 |
Location of the CD8 T Cell Epitope within the Antigenic Precursor Determines Immunogenicity and Protection against the Toxoplasma gondii Parasite V Feliu, V Vasseur, HS Grover, HH Chu, MJ Brown, J Wang, JP Boyle, ... PLoS pathogens 9 (6), e1003449, 2013 | 68 | 2013 |
Whole genome sequencing of a natural recombinant Toxoplasma gondiistrain reveals chromosome sorting and local allelic variants IL Bontell, N Hall, KE Ashelford, JP Dubey, JP Boyle, J Lindh, JE Smith Genome biology 10, 1-17, 2009 | 63 | 2009 |