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The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling S Tuupanen, M Turunen, R Lehtonen, O Hallikas, S Vanharanta, T Kivioja, ... Nature genetics 41 (8), 885-890, 2009 | 598 | 2009 |
The Glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in Lepidoptera V Ahola, R Lehtonen, P Somervuo, L Salmela, P Koskinen, P Rastas, ... Nature communications 5 (1), 4737, 2014 | 239 | 2014 |
Mice lacking a Myc enhancer that includes human SNP rs6983267 are resistant to intestinal tumors IK Sur, O Hallikas, A Vähärautio, J Yan, M Turunen, M Enge, M Taipale, ... Science 338 (6112), 1360-1363, 2012 | 237 | 2012 |
Insights into p53 transcriptional function via genome-wide chromatin occupancy and gene expression analysis F Nikulenkov, C Spinnler, H Li, C Tonelli, Y Shi, M Turunen, T Kivioja, ... Cell Death & Differentiation 19 (12), 1992-2002, 2012 | 227 | 2012 |
Uterine leiomyoma-linked MED12 mutations disrupt mediator-associated CDK activity M Turunen, JM Spaeth, S Keskitalo, MJ Park, T Kivioja, AD Clark, ... Cell reports 7 (3), 654-660, 2014 | 166 | 2014 |
Selective use of multiple vitamin D response elements underlies the 1 α,25-dihydroxyvitamin D3-mediated negative regulation of the human CYP27B1 gene MM Turunen, TW Dunlop, C Carlberg, S Väisänen Nucleic acids research 35 (8), 2734-2747, 2007 | 124 | 2007 |
Mutations in the Circadian Gene CLOCK in Colorectal Cancer P Alhopuro, M Björklund, H Sammalkorpi, M Turunen, S Tuupanen, ... Molecular Cancer Research 8 (7), 952-960, 2010 | 90 | 2010 |
Identification of candidate oncogenes in human colorectal cancers with microsatellite instability AE Gylfe, J Kondelin, M Turunen, H Ristolainen, R Katainen, E Pitkänen, ... Gastroenterology 145 (3), 540-543. e22, 2013 | 77 | 2013 |
CRISPR/Cas9 screening using unique molecular identifiers B Schmierer, SK Botla, J Zhang, M Turunen, T Kivioja, J Taipale Molecular systems biology 13 (10), 945, 2017 | 67 | 2017 |
The number of vitamin D receptor binding sites defines the different vitamin D responsiveness of the CYP24 gene in malignant and normal mammary cells JM Matilainen, M Malinen, MM Turunen, C Carlberg, S Väisänen Journal of Biological Chemistry 285 (31), 24174-24183, 2010 | 47 | 2010 |
Somatic MED12 mutations in prostate cancer and uterine leiomyomas promote tumorigenesis through distinct mechanisms K Kämpjärvi, NH Kim, S Keskitalo, AD Clark, P Von Nandelstadh, ... The Prostate 76 (1), 22-31, 2016 | 44 | 2016 |
Contribution of allelic imbalance to colorectal cancer K Palin, E Pitkänen, M Turunen, B Sahu, P Pihlajamaa, T Kivioja, ... Nature communications 9 (1), 3664, 2018 | 35 | 2018 |
Transcriptional networks controlling the cell cycle M Bonke, M Turunen, M Sokolova, A Vähärautio, T Kivioja, M Taipale, ... G3: Genes| Genomes| Genetics 3 (1), 75-90, 2013 | 32 | 2013 |
Genome-wide screen of cell-cycle regulators in normal and tumor cells identifies a differential response to nucleosome depletion M Sokolova, M Turunen, O Mortusewicz, T Kivioja, P Herr, A Vähärautio, ... Cell cycle 16 (2), 189-199, 2017 | 31 | 2017 |
Oncogenic herpesvirus utilizes stress-induced cell cycle checkpoints for efficient lytic replication G Balistreri, J Viiliäinen, M Turunen, R Diaz, L Lyly, P Pekkonen, ... PLoS pathogens 12 (2), e1005424, 2016 | 31 | 2016 |
Characterization of the colorectal cancer–associated enhancer MYC-335 at 8q24: the role of rs67491583 S Tuupanen, J Yan, M Turunen, AE Gylfe, E Kaasinen, L Li, C Eng, ... Cancer genetics 205 (1-2), 25-33, 2012 | 28 | 2012 |
Myc requires RhoA/SRF to reprogram glutamine metabolism HM Haikala, E Marques, M Turunen, J Klefström Small GTPases 9 (3), 274-282, 2018 | 18 | 2018 |
Pancreatic ductal adenocarcinoma comprises coexisting regulatory states with both common and distinct dependencies P Laise, M Turunen, HC Maurer, AG Curiel, E Elyada, B Schmierer, ... Biorxiv, preprint, 2020 | 16 | 2020 |
Comprehensive evaluation of coding region point mutations in microsatellite‐unstable colorectal cancer J Kondelin, K Salokas, L Saarinen, K Ovaska, H Rauanheimo, RM Plaketti, ... EMBO molecular medicine 10 (9), e8552, 2018 | 16 | 2018 |