Rational design of potent sialidase-based inhibitors of influenza virus replication M Von Itzstein, WY Wu, GB Kok, MS Pegg, JC Dyason, B Jin, T Van Phan, ... Nature 363 (6428), 418-423, 1993 | 2371 | 1993 |
The war against influenza: discovery and development of sialidase inhibitors M Von Itzstein Nature reviews Drug discovery 6 (12), 967-974, 2007 | 828 | 2007 |
NAD+ cleavage activity by animal and plant TIR domains in cell death pathways S Horsefield, H Burdett, X Zhang, MK Manik, Y Shi, J Chen, T Qi, J Gilley, ... Science 365 (6455), 793-799, 2019 | 372 | 2019 |
Molecular modeling studies on ligand binding to sialidase from influenza virus and the mechanism of catalysis NR Taylor, M von Itzstein Journal of medicinal chemistry 37 (5), 616-624, 1994 | 275 | 1994 |
Evidence for a sialosyl cation transition‐state complex in the reaction of sialidase from influenza virus AKJ CHONG, MS PEGG, NR TAYLOR, M von ITZSTEIN European journal of biochemistry 207 (1), 335-343, 1992 | 250 | 1992 |
Recent advances in the synthesis of sialic acid derivatives and sialylmimetics as biological probes MJ Kiefel, M von Itzstein Chemical reviews 102 (2), 471-490, 2002 | 240 | 2002 |
Limited inhibitory effects of oseltamivir and zanamivir on human sialidases K Hata, K Koseki, K Yamaguchi, S Moriya, Y Suzuki, S Yingsakmongkon, ... Antimicrobial agents and chemotherapy 52 (10), 3484-3491, 2008 | 223 | 2008 |
Second sialic acid binding site in Newcastle disease virus hemagglutinin-neuraminidase: implications for fusion V Zaitsev, M von Itzstein, D Groves, M Kiefel, T Takimoto, A Portner, ... Journal of virology 78 (7), 3733-3741, 2004 | 205 | 2004 |
Sialic acid dependence in rotavirus host cell invasion T Haselhorst, FE Fleming, JC Dyason, RD Hartnell, X Yu, G Holloway, ... Nature chemical biology 5 (2), 91-93, 2009 | 189 | 2009 |
Rapid, clean, and mild O-acetylation of alcohols and carbohydrates in an ionic liquid SA Forsyth, DR MacFarlane, RJ Thomson, M Von Itzstein Chemical Communications, 714-715, 2002 | 188 | 2002 |
The synthesis of 2, 3-didehydro-2, 4-dideoxy-4-guanidinyl-N-acetylneuraminic acid: a potent influenza virus sialidase inhibitor M von Itzstein, WY Wu, B Jin Carbohydrate research 259 (2), 301-305, 1994 | 186 | 1994 |
Sialic acid catabolism drives intestinal inflammation and microbial dysbiosis in mice YL Huang, C Chassard, M Hausmann, M Von Itzstein, T Hennet Nature communications 6 (1), 8141, 2015 | 185 | 2015 |
Glycointeractions in bacterial pathogenesis J Poole, CJ Day, M von Itzstein, JC Paton, MP Jennings Nature Reviews Microbiology 16 (7), 440-452, 2018 | 183 | 2018 |
Lysosomal sialidase (neuraminidase-1) is targeted to the cell surface in a multiprotein complex that facilitates elastic fiber assembly A Hinek, AV Pshezhetsky, M Von Itzstein, B Starcher Journal of Biological Chemistry 281 (6), 3698-3710, 2006 | 183 | 2006 |
Inhibition of sialidases from viral, bacterial and mammalian sources by analogues of 2-deoxy-2,3-didehydro-N-acetylneuraminic acid modified at the C-4 position CT Holzer, M Von Itzstein, B Jin, MS Pegg, WP Stewart, WY Wu Glycoconjugate journal 10, 40-44, 1993 | 181 | 1993 |
Sialic acid recognition by Vibrio cholerae neuraminidase I Moustafa, H Connaris, M Taylor, V Zaitsev, JC Wilson, MJ Kiefel, ... Journal of Biological Chemistry 279 (39), 40819-40826, 2004 | 179 | 2004 |
A study of the active site of influenza virus sialidase: an approach to the rational design of novel anti-influenza drugs M von Itzstein, JC Dyason, SW Oliver, HF White, WY Wu, GB Kok, ... Journal of medicinal chemistry 39 (2), 388-391, 1996 | 179 | 1996 |
Analysis of inhibitor binding in influenza virus neuraminidase BJ Smith, PM Colman, M Von Itzstein, B Danylec, JN Varghese Protein Science 10 (4), 689-696, 2001 | 138 | 2001 |
Microbial glycobiology: structures, relevance and applications AP Moran Elsevier, 2009 | 134 | 2009 |
Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase S Rudrawar, JC Dyason, MA Rameix-Welti, FJ Rose, PS Kerry, ... Nature communications 1 (1), 113, 2010 | 122 | 2010 |