SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo YJ Hou, S Chiba, P Halfmann, C Ehre, M Kuroda, KH Dinnon III, SR Leist, ... Science 370 (6523), 1464-1468, 2020 | 956 | 2020 |
A periciliary brush promotes the lung health by separating the mucus layer from airway epithelia B Button, LH Cai, C Ehre, M Kesimer, DB Hill, JK Sheehan, RC Boucher, ... Science 337 (6097), 937-941, 2012 | 871 | 2012 |
Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure AG Henderson, C Ehre, B Button, LH Abdullah, LH Cai, MW Leigh, ... The Journal of clinical investigation 124 (7), 3047-3060, 2014 | 351 | 2014 |
Localization of secretory mucins MUC5AC and MUC5B in normal/healthy human airways K Okuda, G Chen, DB Subramani, M Wolf, RC Gilmore, T Kato, ... American journal of respiratory and critical care medicine 199 (6), 715-727, 2019 | 239 | 2019 |
Molecular organization of the mucins and glycocalyx underlying mucus transport over mucosal surfaces of the airways M Kesimer, C Ehre, KA Burns, CW Davis, JK Sheehan, RJ Pickles Mucosal immunology 6 (2), 379-392, 2013 | 218 | 2013 |
Overexpressing mouse model demonstrates the protective role of Muc5ac in the lungs C Ehre, EN Worthington, RM Liesman, BR Grubb, D Barbier, WK O’Neal, ... Proceedings of the National Academy of Sciences 109 (41), 16528-16533, 2012 | 210 | 2012 |
The ER stress transducer IRE1β is required for airway epithelial mucin production MB Martino, L Jones, B Brighton, C Ehre, L Abdulah, CW Davis, D Ron, ... Mucosal immunology 6 (3), 639-654, 2013 | 200 | 2013 |
Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis CR Esther Jr, MS Muhlebach, C Ehre, DB Hill, MC Wolfgang, M Kesimer, ... Science translational medicine 11 (486), eaav3488, 2019 | 186 | 2019 |
Chronic exposure to beta-blockers attenuates inflammation and mucin content in a murine asthma model LP Nguyen, O Omoluabi, S Parra, JM Frieske, C Clement, ... American journal of respiratory cell and molecular biology 38 (3), 256-262, 2008 | 180 | 2008 |
Cystic fibrosis: an inherited disease affecting mucin-producing organs C Ehre, C Ridley, DJ Thornton The international journal of biochemistry & cell biology 52, 136-145, 2014 | 146 | 2014 |
Munc13‐2−/− baseline secretion defect reveals source of oligomeric mucins in mouse airways Y Zhu, C Ehre, LH Abdullah, JK Sheehan, M Roy, CM Evans, BF Dickey, ... The Journal of physiology 586 (7), 1977-1992, 2008 | 126 | 2008 |
Mucus, mucins, and cystic fibrosis CB Morrison, MR Markovetz, C Ehre Pediatric pulmonology 54, S84-S96, 2019 | 114 | 2019 |
An improved inhaled mucolytic to treat airway muco-obstructive diseases C Ehre, ZL Rushton, B Wang, LN Hothem, CB Morrison, NC Fontana, ... American journal of respiratory and critical care medicine 199 (2), 171-180, 2019 | 98 | 2019 |
Airway mucus hyperconcentration in non–cystic fibrosis bronchiectasis KA Ramsey, ACH Chen, G Radicioni, R Lourie, M Martin, A Broomfield, ... American journal of respiratory and critical care medicine 201 (6), 661-670, 2020 | 84 | 2020 |
Barrier role of actin filaments in regulated mucin secretion from airway goblet cells C Ehre, AH Rossi, LH Abdullah, K De Pestel, S Hill, JC Olsen, CW Davis American Journal of Physiology-Cell Physiology 288 (1), C46-C56, 2005 | 74 | 2005 |
SARS-CoV-2 infection of airway cells causes intense viral and cell shedding, two spreading mechanisms affected by IL-13 CB Morrison, CE Edwards, KM Shaffer, KC Araba, JA Wykoff, DR Williams, ... Proceedings of the National Academy of Sciences 119 (16), e2119680119, 2022 | 69 | 2022 |
Mucin production during prenatal and postnatal murine lung development MG Roy, M Rahmani, JR Hernandez, SN Alexander, C Ehre, SB Ho, ... American Journal of Respiratory Cell and Molecular Biology 44 (6), 755-760, 2011 | 61 | 2011 |
Endotracheal tube mucus as a source of airway mucus for rheological study MR Markovetz, DB Subramani, WJ Kissner, CB Morrison, IC Garbarine, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 317 (4 …, 2019 | 47 | 2019 |
Mucin secretion and PKC isoforms in SPOC1 goblet cells: differential activation by purinergic agonist and PMA LH Abdullah, JT Bundy, C Ehre, CW Davis American Journal of Physiology-Lung Cellular and Molecular Physiology 285 (1 …, 2003 | 47 | 2003 |
Treatment of cystic fibrosis airway cells with CFTR modulators reverses aberrant mucus properties via hydration CB Morrison, KM Shaffer, KC Araba, MR Markovetz, JA Wykoff, ... European Respiratory Journal 59 (2), 2022 | 46 | 2022 |