β1 integrin expression by podocytes is required to maintain glomerular structural integrity A Pozzi, G Jarad, GW Moeckel, S Coffa, X Zhang, L Gewin, V Eremina, ... Developmental biology 316 (2), 288-301, 2008 | 224 | 2008 |
Renal fibrosis: primacy of the proximal tubule LS Gewin Matrix Biology 68, 248-262, 2018 | 202 | 2018 |
Progression of chronic kidney disease: too much cellular talk causes damage L Gewin, R Zent, A Pozzi Kidney international 91 (3), 552-560, 2017 | 147 | 2017 |
How does TGF-β mediate tubulointerstitial fibrosis? L Gewin, R Zent Seminars in nephrology 32 (3), 228-235, 2012 | 108 | 2012 |
TGF-β promotes fibrosis after severe acute kidney injury by enhancing renal macrophage infiltration S Chung, JM Overstreet, Y Li, Y Wang, A Niu, S Wang, X Fan, K Sasaki, ... JCI insight 3 (21), 2018 | 101 | 2018 |
Deleting the TGF-β receptor attenuates acute proximal tubule injury L Gewin, S Vadivelu, S Neelisetty, MB Srichai, P Paueksakon, A Pozzi, ... Journal of the American Society of Nephrology 23 (12), 2001-2011, 2012 | 90 | 2012 |
Renal fibrosis is not reduced by blocking transforming growth factor-β signaling in matrix-producing interstitial cells S Neelisetty, C Alford, K Reynolds, L Woodbury, S Nlandu-Khodo, H Yang, ... Kidney international 88 (3), 503-514, 2015 | 83 | 2015 |
Proximal tubule ATR regulates DNA repair to prevent maladaptive renal injury responses S Kishi, CR Brooks, K Taguchi, T Ichimura, Y Mori, A Akinfolarin, N Gupta, ... The Journal of clinical investigation 129 (11), 4797-4816, 2019 | 81 | 2019 |
β1 integrin is necessary for ureteric bud branching morphogenesis and maintenance of collecting duct structural integrity X Zhang, G Mernaugh, DH Yang, L Gewin, MB Srichai, RC Harris, ... Development 136 (19), 3357-3366, 2009 | 80 | 2009 |
Integrin-mediated type II TGF-β receptor tyrosine dephosphorylation controls SMAD-dependent profibrotic signaling X Chen, H Wang, HJ Liao, W Hu, L Gewin, G Mernaugh, S Zhang, ... The Journal of clinical investigation 124 (8), 3295-3310, 2014 | 78 | 2014 |
Sugar or fat? Renal tubular metabolism reviewed in health and disease LS Gewin Nutrients 13 (5), 1580, 2021 | 67 | 2021 |
Selective activation of epidermal growth factor receptor in renal proximal tubule induces tubulointerstitial fibrosis JM Overstreet, Y Wang, X Wang, A Niu, LS Gewin, B Yao, RC Harris, ... The FASEB Journal 31 (10), 4407, 2017 | 67 | 2017 |
Pharmacologic blockade of αvβ1 integrin ameliorates renal failure and fibrosis in vivo Y Chang, WL Lau, H Jo, K Tsujino, L Gewin, NI Reed, A Atakilit, ... Journal of the American Society of Nephrology 28 (7), 1998-2005, 2017 | 63 | 2017 |
Blocking TGF-β and β-catenin epithelial crosstalk exacerbates CKD S Nlandu-Khodo, S Neelisetty, M Phillips, M Manolopoulou, G Bhave, ... Journal of the American Society of Nephrology 28 (12), 3490-3503, 2017 | 61 | 2017 |
TGF-β receptor deletion in the renal collecting system exacerbates fibrosis L Gewin, N Bulus, G Mernaugh, G Moeckel, RC Harris, HL Moses, A Pozzi, ... Journal of the American Society of Nephrology 21 (8), 1334-1343, 2010 | 54 | 2010 |
Wnt/β-catenin in acute kidney injury and progression to chronic kidney disease T Huffstater, WD Merryman, LS Gewin Seminars in nephrology 40 (2), 126-137, 2020 | 47 | 2020 |
Cytometry‐based single‐cell analysis of intact epithelial signaling reveals MAPK activation divergent from TNF‐α‐induced apoptosis in vivo AJ Simmons, A Banerjee, ET McKinley, CR Scurrah, CA Herring, ... Molecular systems biology 11 (10), 835, 2015 | 46 | 2015 |
Transforming growth factor-β in the acute kidney injury to chronic kidney disease transition LS Gewin Nephron 143 (3), 154-157, 2019 | 42 | 2019 |
Peroxidasin and eosinophil peroxidase, but not myeloperoxidase, contribute to renal fibrosis in the murine unilateral ureteral obstruction model S Colon, H Luan, Y Liu, C Meyer, L Gewin, G Bhave American Journal of Physiology-Renal Physiology 316 (2), F360-F371, 2019 | 38 | 2019 |
Renal tubule repair: is Wnt/β-catenin a friend or foe? LS Gewin Genes 9 (2), 58, 2018 | 31 | 2018 |