Artemisinin as an anticancer drug: Recent advances in target profiling and mechanisms of action YK Wong, C Xu, KA Kalesh, Y He, Q Lin, WSF Wong, HM Shen, J Wang Medicinal research reviews 37 (6), 1492-1517, 2017 | 218 | 2017 |
Key cell signaling pathways modulated by zerumbone: role in the prevention and treatment of cancer R Prasannan, KA Kalesh, MK Shanmugam, A Nachiyappan, ... Biochemical pharmacology 84 (10), 1268-1276, 2012 | 151 | 2012 |
Target identification of natural and traditional medicines with quantitative chemical proteomics approaches J Wang, L Gao, YM Lee, KA Kalesh, YS Ong, J Lim, JE Jee, H Sun, ... Pharmacology & Therapeutics 162, 10-22, 2016 | 125 | 2016 |
Global profiling of protein lipidation using chemical proteomic technologies EW Tate, KA Kalesh, T Lanyon-Hogg, EM Storck, E Thinon Current opinion in chemical biology 24, 48-57, 2015 | 116 | 2015 |
The quest for novel antimicrobial compounds: emerging trends in research, development, and technologies PK Mantravadi, KA Kalesh, RCJ Dobson, AO Hudson, A Parthasarathy Antibiotics 8 (1), 8, 2019 | 105 | 2019 |
High-throughput synthesis of azide libraries suitable for direct “click” chemistry and in situ screening R Srinivasan, LP Tan, H Wu, PY Yang, KA Kalesh, SQ Yao Organic & Biomolecular Chemistry 7 (9), 1821-1828, 2009 | 98 | 2009 |
High-Throughput Discovery of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B (MptpB) Inhibitors Using Click Chemistry LP Tan, H Wu, PY Yang, KA Kalesh, X Zhang, M Hu, R Srinivasan, ... Organic Letters 11 (22), 5102-5105, 2009 | 87 | 2009 |
The use of click chemistry in the emerging field of catalomics KA Kalesh, H Shi, J Ge, SQ Yao Organic & Biomolecular Chemistry 8 (8), 1749-1762, 2010 | 73 | 2010 |
Peptide-based activity-based probes (ABPs) for target-specific profiling of protein tyrosine phosphatases (PTPs) KA Kalesh, LP Tan, K Lu, L Gao, J Wang, SQ Yao Chemical communications 46 (4), 589-591, 2010 | 69 | 2010 |
Methods of using click chemistry in the discovery of enzyme inhibitors R Srinivasan, J Li, SL Ng, KA Kalesh, SQ Yao Nature protocols 2 (11), 2655-2664, 2007 | 59 | 2007 |
Rapid synthesis of Abelson tyrosine kinase inhibitors using click chemistry KA Kalesh, K Liu, SQ Yao Organic & Biomolecular Chemistry 7 (24), 5129-5136, 2009 | 52 | 2009 |
Small molecule probes that target Abl kinase KA Kalesh, DSB Sim, J Wang, K Liu, Q Lin, SQ Yao Chemical communications 46 (7), 1118-1120, 2010 | 49 | 2010 |
An integrated chemical proteomics approach for quantitative profiling of intracellular ADP-ribosylation K Kalesh, S Lukauskas, AJ Borg, AP Snijders, V Ayyappan, AKL Leung, ... Scientific reports 9 (1), 6655, 2019 | 34 | 2019 |
Recent advances in synthesis and identification of cyclic peptides for bioapplications Y Siang Ong, L Gao, K A Kalesh, Z Yu, J Wang, C Liu, Y Li, H Sun, ... Current topics in medicinal chemistry 17 (20), 2302-2318, 2017 | 33 | 2017 |
Competition-based, quantitative chemical proteomics in breast cancer cells identifies new target profiles for sulforaphane JA Clulow, EM Storck, T Lanyon-Hogg, KA Kalesh, LH Jones, EW Tate Chemical Communications 53 (37), 5182-5185, 2017 | 33 | 2017 |
Target profiling of zerumbone using a novel cell-permeable clickable probe and quantitative chemical proteomics KA Kalesh, JA Clulow, EW Tate Chemical Communications 51 (25), 5497-5500, 2015 | 33 | 2015 |
Click Chemistry as a High‐Throughput Amenable Platform in Catalomics KA Kalesh, PY Yang, R Srinivasan, SQ Yao QSAR & Combinatorial Science 26 (11‐12), 1135-1144, 2007 | 32 | 2007 |
Defeating the trypanosomatid trio: proteomics of the protozoan parasites causing neglected tropical diseases A Parthasarathy, K Kalesh RSC Medicinal Chemistry 11, 625-645, 2020 | 21 | 2020 |
A capillary electrophoresis method to explore the self‐assembly of a novel polypeptide ligand with quantum dots J Wang, C Zhang, L Liu, KA Kalesh, L Qiu, S Ding, M Fu, L Gao, P Jiang Electrophoresis 37 (15-16), 2156-2162, 2016 | 19 | 2016 |
An Improved Mechanism‐Based Cross‐Linker for Multiplexed Kinase Detection and Inhibition in a Complex Proteome K Liu, KA Kalesh, L Bing Ong, SQ Yao ChemBioChem 9 (12), 1883-1888, 2008 | 19 | 2008 |