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| Hyperphosphorylation induces self-assembly of τ into tangles of paired helical filaments/straight filaments AC Alonso, T Zaidi, M Novak, I Grundke-Iqbal, K Iqbal Proceedings of the National Academy of Sciences 98 (12), 6923-6928, 2001 | 1185 | 2001 |
| Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules AC Alonso, I Grundke-Iqbal, K Iqbal Nature medicine 2 (7), 783-787, 1996 | 1060 | 1996 |
| Microtubule-associated protein tau. Abnormal phosphorylation of a non-paired helical filament pool in Alzheimer disease. E Köpke, YC Tung, S Shaikh, AC Alonso, K Iqbal, I Grundke-Iqbal Journal of Biological Chemistry 268 (32), 24374-24384, 1993 | 1037 | 1993 |
| Role of abnormally phosphorylated tau in the breakdown of microtubules in Alzheimer disease. AC Alonso, T Zaidi, I Grundke-Iqbal, K Iqbal Proceedings of the National Academy of Sciences 91 (12), 5562-5566, 1994 | 935 | 1994 |
| Mechanisms of tau-induced neurodegeneration K Iqbal, F Liu, CX Gong, AC Alonso, I Grundke-Iqbal Acta neuropathologica 118, 53-69, 2009 | 803 | 2009 |
| Abnormal phosphorylation of tau and the mechanism of Alzheimer neurofibrillary degeneration: sequestration of microtubule-associated proteins 1 and 2 and the disassembly of … AC Alonso, I Grundke-Iqbal, HS Barra, K Iqbal Proceedings of the national academy of sciences 94 (1), 298-303, 1997 | 576 | 1997 |
| Promotion of hyperphosphorylation by frontotemporal dementia tau mutations AC Alonso, A Mederlyova, M Novak, I Grundke-Iqbal, K Iqbal Journal of Biological Chemistry 279 (33), 34873-34881, 2004 | 423 | 2004 |
| Phosphorylation of tau at Thr212, Thr231, and Ser262 combined causes neurodegeneration AD Alonso, J Di Clerico, B Li, CP Corbo, ME Alaniz, I Grundke-Iqbal, ... Journal of Biological Chemistry 285 (40), 30851-30860, 2010 | 243 | 2010 |
| Polymerization of hyperphosphorylated tau into filaments eliminates its inhibitory activity AC Alonso, B Li, I Grundke-Iqbal, K Iqbal Proceedings of the National Academy of Sciences 103 (23), 8864-8869, 2006 | 243 | 2006 |
| Hyperphosphorylation of tau associates with changes in its function beyond microtubule stability AD Alonso, LS Cohen, C Corbo, V Morozova, A ElIdrissi, G Phillips, ... Frontiers in cellular neuroscience 12, 338, 2018 | 219 | 2018 |
| Interaction of tau isoforms with Alzheimer's disease abnormally hyperphosphorylated tau and in VitroPhosphorylation into the disease-like protein AC Alonso, T Zaidi, M Novak, HS Barra, I Grundke-Iqbal, K Iqbal Journal of Biological Chemistry 276 (41), 37967-37973, 2001 | 206 | 2001 |
| Mechanisms of neurofibrillary degeneration and the formation of neurofibrillary tangles K Iqbal, A del C. Alonso, CX Gong, S Khatoon, JJ Pei, JZ Wang, ... Ageing and Dementia, 169-180, 1998 | 199 | 1998 |
| Mechanism of tau-induced neurodegeneration in Alzheimer disease and related tauopathies AC Alonso, B Li, I Grundke-Iqbal, K Iqbal Current Alzheimer Research 5 (4), 375-384, 2008 | 169 | 2008 |
| Abnormal tau induces cognitive impairment through two different mechanisms: synaptic dysfunction and neuronal loss J Di, LS Cohen, CP Corbo, GR Phillips, A El Idrissi, AD Alonso Scientific reports 6 (1), 20833, 2016 | 121 | 2016 |
| Fluorescent porous carbon nanocapsules for two-photon imaging, NIR/pH dual-responsive drug carrier, and photothermal therapy H Wang, Y Sun, J Yi, J Fu, J Di, A del Carmen Alonso, S Zhou Biomaterials 53, 117-126, 2015 | 114 | 2015 |
| Tau-induced neurodegeneration: mechanisms and targets C Beharry, LS Cohen, J Di, K Ibrahim, S Briffa-Mirabella, AC Alonso Neuroscience bulletin 30, 346-358, 2014 | 106 | 2014 |
| Mechanism of neurofibrillary degeneration and pharmacologic therapeutic approach K Iqbal, AC Del Alonso, JA Gondal, CX Gong, N Haque, S Khatoon, ... Advances in Dementia Research, 213-222, 2000 | 96 | 2000 |
| Mechanism of neurofibrillary degeneration in Alzheimer's disease K Iqbal, AC Alonso, CX Gong, S Khatoon, TJ Singh, I Grundke-Iqbal Molecular neurobiology 9, 119-123, 1994 | 93 | 1994 |
| “Clicked” sugar–curcumin conjugate: modulator of amyloid-β and tau peptide aggregation at ultralow concentrations S Dolai, W Shi, C Corbo, C Sun, S Averick, D Obeysekera, M Farid, ... ACS chemical neuroscience 2 (12), 694-699, 2011 | 87 | 2011 |
