Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive E Jacinto, R Loewith, A Schmidt, S Lin, MA Rüegg, A Hall, MN Hall Nature cell biology 6 (11), 1122-1128, 2004 | 2755 | 2004 |
Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control R Loewith, E Jacinto, S Wullschleger, A Lorberg, JL Crespo, D Bonenfant, ... Molecular cell 10 (3), 457-468, 2002 | 2353 | 2002 |
SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity E Jacinto, V Facchinetti, D Liu, N Soto, S Wei, SY Jung, Q Huang, J Qin, ... Cell 127 (1), 125-137, 2006 | 1759 | 2006 |
JNK is involved in signal integration during costimulation of T lymphocytes B Su, E Jacinto, M Hibi, T Kallunki, M Karin, Y Ben-Neriah Cell 77 (5), 727-736, 1994 | 1151 | 1994 |
Tor signalling in bugs, brain and brawn E Jacinto, MN Hall Nature reviews Molecular cell biology 4 (2), 117-126, 2003 | 761 | 2003 |
mTOR complex 2 signaling and functions WJ Oh, E Jacinto Cell cycle 10 (14), 2305-2316, 2011 | 702 | 2011 |
The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C V Facchinetti, W Ouyang, H Wei, N Soto, A Lazorchak, C Gould, C Lowry, ... The EMBO journal 27 (14), 1932-1943, 2008 | 651 | 2008 |
mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide WJ Oh, C Wu, SJ Kim, V Facchinetti, LA Julien, M Finlan, PP Roux, B Su, ... The EMBO journal 29 (23), 3939-3951, 2010 | 381 | 2010 |
Regulation and metabolic functions of mTORC1 and mTORC2 A Szwed, E Kim, E Jacinto Physiological reviews 101 (3), 1371-1426, 2021 | 361 | 2021 |
Calcineurin preferentially synergizes with PKC‐θ to activate JNK and IL‐2 promoter in T lymphocytes G Werlen, E Jacinto, Y Xia, M Karin The EMBO journal, 1998 | 343 | 1998 |
TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway E Jacinto, B Guo, KT Arndt, T Schmelzle, MN Hall Molecular cell 8 (5), 1017-1026, 2001 | 292 | 2001 |
TOR regulation of AGC kinases in yeast and mammals E Jacinto, A Lorberg Biochemical Journal 410 (1), 19-37, 2008 | 254 | 2008 |
Targeting mTOR and metabolism in cancer: lessons and innovations C Magaway, E Kim, E Jacinto Cells 8 (12), 1584, 2019 | 189 | 2019 |
Molecular Cloning and Characterization of Human JNKK2, a Novel Jun NH2-Terminal Kinase-Specific Kinase Z Wu, J Wu, E Jacinto, M Karin Molecular and cellular biology 17 (12), 7407-7416, 1997 | 149 | 1997 |
Quantitation of changes in protein phosphorylation: a simple method based on stable isotope labeling and mass spectrometry D Bonenfant, T Schmelzle, E Jacinto, JL Crespo, T Mini, MN Hall, P Jenoe Proceedings of the National Academy of Sciences 100 (3), 880-885, 2003 | 146 | 2003 |
Cooperation between Syk and Rac1 leads to synergistic JNK activation in T lymphocytes E Jacinto, G Werlen, M Karin Immunity 8 (1), 31-41, 1998 | 146 | 1998 |
mTORC2 responds to glutamine catabolite levels to modulate the hexosamine biosynthesis enzyme GFAT1 JG Moloughney, PK Kim, NM Vega-Cotto, CC Wu, S Zhang, M Adlam, ... Molecular cell 63 (5), 811-826, 2016 | 121 | 2016 |
mTOR complex 2 regulates proper turnover of insulin receptor substrate-1 via the ubiquitin ligase subunit Fbw8 SJ Kim, MA DeStefano, WJ Oh, C Wu, NM Vega-Cotto, M Finlan, D Liu, ... Molecular cell 48 (6), 875-887, 2012 | 109 | 2012 |
Mammalian TOR signaling to the AGC kinases B Su, E Jacinto Critical reviews in biochemistry and molecular biology 46 (6), 527-547, 2011 | 86 | 2011 |
Regulation of insulin receptor substrate-1 by mTORC2 (mammalian target of rapamycin complex 2) MA DeStefano, E Jacinto Biochemical society transactions 41 (4), 896-901, 2013 | 56 | 2013 |