Direct activation of human and mouse Oct4 genes using engineered TALE and Cas9 transcription factors J Hu, Y Lei, WK Wong, S Liu, KC Lee, X He, W You, R Zhou, JT Guo, ... Nucleic acids research 42 (7), 4375-4390, 2014 | 183 | 2014 |
Purity independent subtyping of tumors (PurIST), a clinically robust, single-sample classifier for tumor subtyping in pancreatic cancer NU Rashid, XL Peng, C Jin, RA Moffitt, KE Volmar, BA Belt, RZ Panni, ... Clinical Cancer Research 26 (1), 82-92, 2020 | 144 | 2020 |
Plasma DNA aberrations in systemic lupus erythematosus revealed by genomic and methylomic sequencing RWY Chan, P Jiang, X Peng, LS Tam, GJW Liao, EKM Li, PCH Wong, ... Proceedings of the National Academy of Sciences 111 (49), E5302-E5311, 2014 | 131 | 2014 |
Bioinformatics approaches for fetal DNA fraction estimation in noninvasive prenatal testing XL Peng, P Jiang International journal of molecular sciences 18 (2), 453, 2017 | 78 | 2017 |
MyoD-and FoxO3-mediated hotspot interaction orchestrates super-enhancer activity during myogenic differentiation XL Peng, KK So, L He, Y Zhao, J Zhou, Y Li, M Yao, B Xu, S Zhang, H Yao, ... Nucleic Acids Research, 2017 | 58 | 2017 |
Isoforms of MUC16 activate oncogenic signaling through EGF receptors to enhance the progression of pancreatic cancer D Thomas, S Sagar, X Liu, HR Lee, JA Grunkemeyer, PM Grandgenett, ... Molecular Therapy 29 (4), 1557-1571, 2021 | 45 | 2021 |
De novo compartment deconvolution and weight estimation of tumor samples using DECODER XL Peng, RA Moffitt, RJ Torphy, KE Volmar, JJ Yeh Nature communications 10 (1), 4729, 2019 | 40 | 2019 |
DNase1 does not appear to play a major role in the fragmentation of plasma DNA in a knockout mouse model THT Cheng, KO Lui, XL Peng, SH Cheng, P Jiang, KCA Chan, RWK Chiu, ... Clinical chemistry 64 (2), 406-408, 2018 | 39 | 2018 |
FetalQuantSD: accurate quantification of fetal DNA fraction by shallow-depth sequencing of maternal plasma DNA P Jiang, X Peng, X Su, K Sun, SCY Yu, WI Chu, TY Leung, H Sun, ... NPJ genomic medicine 1 (1), 1-7, 2016 | 39 | 2016 |
Single-cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal tree AM Hendley, AA Rao, L Leonhardt, S Ashe, JA Smith, S Giacometti, ... Elife 10, e67776, 2021 | 30 | 2021 |
CRISPR/Cas9/AAV9-mediated in vivo editing identifies MYC regulation of 3D genome in skeletal muscle stem cell L He, Y Ding, Y Zhao, KK So, XL Peng, Y Li, J Yuan, Z He, X Chen, H Sun, ... Stem Cell Reports 16 (10), 2442-2458, 2021 | 29 | 2021 |
Irreversible JNK1-JUN inhibition by JNK-IN-8 sensitizes pancreatic cancer to 5-FU/FOLFOX chemotherapy MB Lipner, XL Peng, C Jin, Y Xu, Y Gao, MP East, NU Rashid, RA Moffitt, ... JCI insight 5 (8), 2020 | 26 | 2020 |
Truncated O-Glycan-Bearing MUC16 enhances pancreatic cancer cells aggressiveness via α4β1 integrin complexes and FAK signaling C Rajesh, S Sagar, AK Rathinavel, DT Chemparathy, XL Peng, JJ Yeh, ... International journal of molecular sciences 23 (10), 5459, 2022 | 9 | 2022 |
Sub-Cluster Identification through Semi-Supervised Optimization of Rare-Cell Silhouettes (SCISSORS) in single-cell RNA-sequencing JR Leary, Y Xu, AB Morrison, C Jin, EC Shen, PC Kuhlers, Y Su, ... Bioinformatics 39 (8), btad449, 2023 | 8 | 2023 |
Open-source curation of a pancreatic ductal adenocarcinoma gene expression analysis platform (pdacR) supports a two-subtype model LA Torre-Healy, RR Kawalerski, K Oh, L Chrastecka, XL Peng, AJ Aguirre, ... Communications Biology 6 (1), 163, 2023 | 6 | 2023 |
Whole genome chromatin IP-sequencing (ChIP-Seq) in skeletal muscle cells KK So, XL Peng, H Sun, H Wang Skeletal Muscle Development, 15-25, 2017 | 6 | 2017 |
In Vivo Study of Key Transcription Factors in Muscle Satellite Cells by CRISPR/Cas9/AAV9-sgRNA Mediated Genome Editing L He, Y Ding, Y Zhao, KK So, XL Peng, Y Li, J Yuan, H Sun, H Wang bioRxiv, 797746, 2019 | 3 | 2019 |
Bioinformatics Pipeline for Accurate Quantification of Fetal DNA Fraction in Maternal Plasma M Ni, XL Peng, P Jiang Cell-free DNA as Diagnostic Markers: Methods and Protocols, 177-180, 2019 | 2 | 2019 |
Bioinformatics for novel long intergenic noncoding RNA (lincRNA) identification in skeletal muscle cells X Peng, K Sun, J Zhou, H Sun, H Wang Muscle Stem Cells: Methods and Protocols, 355-362, 2017 | 2 | 2017 |
Efficient computation of high-dimensional penalized generalized linear mixed models by latent factor modeling of the random effects HM Heiling, NU Rashid, Q Li, XL Peng, JJ Yeh, JG Ibrahim Biometrics 80 (1), ujae016, 2024 | 1 | 2024 |