| Class III antiarrhythmic agents have a lot of potential but a long way to go. Reduced effectiveness and dangers of reverse use dependence. LM Hondeghem, DJ Snyders Circulation 81 (2), 686-690, 1990 | 774 | 1990 |
| Structure and function of cardiac potassium channels DJ Snyders Cardiovascular research 42 (2), 377-390, 1999 | 348 | 1999 |
| A rapidly activating and slowly inactivating potassium channel cloned from human heart. Functional analysis after stable mammalian cell culture expression. DJ Snyders, MM Tamkun, PB Bennett The Journal of General Physiology 101 (4), 513-543, 1993 | 336 | 1993 |
| High affinity open channel block by dofetilide of HERG expressed in a human cell line. DJ Snyders, A Chaudhary Molecular pharmacology 49 (6), 949-955, 1996 | 286 | 1996 |
| Stereoselective block of cardiac sodium channels by bupivacaine in guinea pig ventricular myocytes C Valenzuela, DJ Snyders, PB Bennett, J Tamargo, LM Hondeghem Circulation 92 (10), 3014-3024, 1995 | 282 | 1995 |
| Heteromultimeric assembly of human potassium channels. Molecular basis of a transient outward current? S Po, S Roberds, DJ Snyders, MM Tamkun, PB Bennett Circulation research 72 (6), 1326-1336, 1993 | 231 | 1993 |
| Stereoselective block of a human cardiac potassium channel (Kv1. 5) by bupivacaine enantiomers C Valenzuela, E Delpon, MM Tamkun, J Tamargo, DJ Snyders Biophysical Journal 69 (2), 418-427, 1995 | 230 | 1995 |
| Ibutilide, a Methanesulfonanilide Antiarrhythmic, Is a Potent Blocker of the Rapidly Activating Delayed Rectifier K+ Current (IKr) in AT-1 Cells: Concentration-, Time … T Yang, DJ Snyders, DM Roden Circulation 91 (6), 1799-1806, 1995 | 225 | 1995 |
| Rapid Inactivation Determines the Rectification and [K+]o Dependence of the Rapid Component of the Delayed Rectifier K+ Current in Cardiac Cells T Yang, DJ Snyders, DM Roden Circulation Research 80 (6), 782-789, 1997 | 212 | 1997 |
| Obligatory heterotetramerization of three previously uncharacterized Kv channel α-subunits identified in the human genome N Ottschytsch, A Raes, D Van Hoorick, DJ Snyders Proceedings of the National Academy of Sciences 99 (12), 7986-7991, 2002 | 210 | 2002 |
| Drug block of I Kr: model systems and relevance to human arrhythmias T Yang, D Snyders, DM Roden Journal of cardiovascular pharmacology 38 (5), 737-744, 2001 | 198 | 2001 |
| A K+ channel splice variant common in human heart lacks a C-terminal domain required for expression of rapidly activating delayed rectifier current S Kupershmidt, DJ Snyders, A Raes, DM Roden Journal of Biological Chemistry 273 (42), 27231-27235, 1998 | 182 | 1998 |
| Functional differences in Kv1. 5 currents expressed in mammalian cell lines are due to the presence of endogenous Kvβ2. 1 subunits VN Uebele, SK England, A Chaudhary, MM Tamkun, DJ Snyders Journal of Biological Chemistry 271 (5), 2406-2412, 1996 | 165 | 1996 |
| Molecular Analysis of a Binding Site for Quinidine in a Human Cardiac Delayed Rectifier K+ Channel: Role of S6 in Antiarrhythmic Drug Binding SW Yeola, TC Rich, VN Uebele, MM Tamkun, DJ Snyders Circulation Research 78 (6), 1105-1114, 1996 | 161 | 1996 |
| The contribution of genes involved in potassium‐recycling in the inner ear to noise‐induced hearing loss L Van Laer, PI Carlsson, N Ottschytsch, ML Bondeson, A Konings, ... Human mutation 27 (8), 786-795, 2006 | 159 | 2006 |
| Determinants of antiarrhythmic drug action: electrostatic and hydrophobic components of block of the human cardiac hKv1. 5 channel DJ Snyders, SW Yeola Circulation Research 77 (3), 575-583, 1995 | 152 | 1995 |
| Quinidine delays IK activation in guinea pig ventricular myocytes. DM Roden, PB Bennett, DJ Snyders, JR Balser, LM Hondeghem Circulation Research 62 (5), 1055-1058, 1988 | 150 | 1988 |
| Electrophysiological and pharmacological correspondence between Kv4. 2 current and rat cardiac transient outward current SW Yeola, DJ Snyders Cardiovascular research 33 (3), 540-547, 1997 | 126 | 1997 |
| A novel mutation (T65P) in the PAS domain of the human potassium channel HERG results in the long QT syndrome by trafficking deficiency A Paulussen, A Raes, G Matthijs, DJ Snyders, N Cohen, J Aerssens Journal of Biological Chemistry 277 (50), 48610-48616, 2002 | 121 | 2002 |
| Molecular determinants of stereoselective bupivacaine block of hKv1. 5 channels L Franqueza, M Longobardo, J Vicente, E Delpón, MM Tamkun, ... Circulation research 81 (6), 1053-1064, 1997 | 111 | 1997 |
