Emodin, an anthraquinone derivative isolated from the rhizomes of Rheum palmatum, selectively inhibits the activity of casein kinase II as a competitive inhibitor H Yim, YH Lee, CH Lee, SK Lee Planta medica 65 (01), 9-13, 1999 | 232 | 1999 |
Current clinical trials with polo-like kinase 1 inhibitors in solid tumors H Yim Anti-cancer drugs 24 (10), 999-1006, 2013 | 112 | 2013 |
Polo-like kinase 1 depletion induces DNA damage in early S prior to caspase activation H Yim, RL Erikson Molecular and cellular biology 29 (10), 2609-2621, 2009 | 92 | 2009 |
Molecular targets of genistein and its related flavonoids to exert anticancer effects HS Chae, R Xu, JY Won, YW Chin, H Yim International Journal of Molecular Sciences 20 (10), 2420, 2019 | 90 | 2019 |
Ginsenoside-Rh2-induced mitochondrial depolarization and apoptosis are associated with reactive oxygen species-and Ca2+-mediated c-Jun NH2-terminal kinase 1 activation in HeLa … YM Ham, JH Lim, HK Na, JS Choi, BD Park, H Yim, SK Lee Journal of Pharmacology and Experimental Therapeutics 319 (3), 1276-1285, 2006 | 89 | 2006 |
Roles of the phosphorylation of transcriptional factors in epithelial‐mesenchymal transition R Xu, JY Won, CH Kim, DE Kim, H Yim Journal of oncology 2019 (1), 5810465, 2019 | 68 | 2019 |
Active PLK1-driven metastasis is amplified by TGF-β signaling that forms a positive feedback loop in non-small cell lung cancer SB Shin, HR Jang, R Xu, JY Won, H Yim Oncogene 39 (4), 767-785, 2020 | 65 | 2020 |
Predictive value of urinary and serum biomarkers in young children with febrile urinary tract infections HE Yim, H Yim, ES Bae, SU Woo, KH Yoo Pediatric Nephrology 29, 2181-2189, 2014 | 63 | 2014 |
Cdk2 activity is associated with depolarization of mitochondrial membrane potential during apoptosis YH Jin, H Yim, JH Park, SK Lee Biochemical and Biophysical Research Communications 305 (4), 974-980, 2003 | 63 | 2003 |
PLK1/vimentin signaling facilitates immune escape by recruiting Smad2/3 to PD-L1 promoter in metastatic lung adenocarcinoma HR Jang, SB Shin, CH Kim, JY Won, R Xu, DE Kim, H Yim Cell Death & Differentiation 28 (9), 2745-2764, 2021 | 62 | 2021 |
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase H Yim, RL Erikson Proceedings of the National Academy of Sciences 107 (46), 19742-19747, 2010 | 58 | 2010 |
Plk1-targeted therapies in TP53-or RAS-mutated cancer H Yim, RL Erikson Mutation Research/Reviews in Mutation Research 761, 31-39, 2014 | 51 | 2014 |
Caspase-3-mediated cleavage of Cdc6 induces nuclear localization of p49-truncated Cdc6 and apoptosis H Yim, YH Jin, BD Park, HJ Choi, SK Lee Molecular biology of the cell 14 (10), 4250-4259, 2003 | 50 | 2003 |
The accumulation of DNA repair defects is the molecular origin of carcinogenesis HJ Cha, H Yim Tumor Biology 34, 3293-3302, 2013 | 48 | 2013 |
Nek1 and TAZ interact to maintain normal levels of polycystin 2 H Yim, CK Sung, J You, Y Tian, T Benjamin Journal of the American Society of Nephrology 22 (5), 832-837, 2011 | 45 | 2011 |
Cleavage of Cdc6 by caspase-3 promotes ATM/ATR kinase–mediated apoptosis of HeLa cells H Yim, IS Hwang, JS Choi, KH Chun, YH Jin, YM Ham, KY Lee, SK Lee The Journal of cell biology 174 (1), 77-88, 2006 | 43 | 2006 |
Cotargeting Plk1 and androgen receptor enhances the therapeutic sensitivity of paclitaxel-resistant prostate cancer SB Shin, SU Woo, H Yim Therapeutic Advances in Medical Oncology 11, 1758835919846375, 2019 | 39 | 2019 |
Cyclin-dependent protein kinase 2 activity is required for mitochondrial translocation of Bax and disruption of mitochondrial transmembrane potential during etoposide-induced … JS Choi, S Shin, YH Jin, H Yim, KT Koo, KH Chun, YT Oh, WH Lee, ... Apoptosis 12, 1229-1241, 2007 | 32 | 2007 |
Nrf2‐lncRNA controls cell fate by modulating p53‐dependent Nrf2 activation as an miRNA sponge for Plk2 and p21cip1 MS Joo, SB Shin, EJ Kim, HJ Koo, H Yim, SG Kim The FASEB Journal 33 (7), 7953-7969, 2019 | 31 | 2019 |
Sensitivity of TP53‐Mutated Cancer Cells to the Phytoestrogen Genistein Is Associated With Direct Inhibition of Plk1 Activity SB Shin, SU Woo, YW Chin, YJ Jang, H Yim Journal of Cellular Physiology 232 (10), 2818-2828, 2017 | 31 | 2017 |