A non-viral CRISPR/Cas9 delivery system for therapeutically targeting HBV DNA and pcsk9 in vivo C Jiang, M Mei, B Li, X Zhu, W Zu, Y Tian, Q Wang, Y Guo, Y Dong, X Tan Cell research 27 (3), 440-443, 2017 | 302 | 2017 |
An orthogonal array optimization of lipid-like nanoparticles for mRNA delivery in vivo B Li, X Luo, B Deng, J Wang, DW McComb, Y Shi, KML Gaensler, X Tan, ... Nano letters 15 (12), 8099-8107, 2015 | 234 | 2015 |
Nanoscale platforms for messenger RNA delivery B Li, X Zhang, Y Dong Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 11 (2 …, 2019 | 165 | 2019 |
Effects of chemically modified messenger RNA on protein expression B Li, X Luo, Y Dong Bioconjugate chemistry 27 (3), 849-853, 2016 | 150 | 2016 |
Engineering CRISPR–Cpf1 crRNAs and mRNAs to maximize genome editing efficiency B Li, W Zhao, X Luo, X Zhang, C Li, C Zeng, Y Dong Nature biomedical engineering 1 (5), 0066, 2017 | 125 | 2017 |
Two-photon near infrared fluorescent turn-on probe toward cysteine and its imaging applications J Wang, B Li, W Zhao, X Zhang, X Luo, ME Corkins, SL Cole, C Wang, ... Acs Sensors 1 (7), 882-887, 2016 | 116 | 2016 |
p38 inhibition provides anti–DNA virus immunity by regulation of USP21 phosphorylation and STING activation Y Chen, L Wang, J Jin, Y Luan, C Chen, Y Li, H Chu, X Wang, G Liao, ... Journal of Experimental Medicine 214 (4), 991-1010, 2017 | 98 | 2017 |
Lipid polymer hybrid nanomaterials for mRNA delivery W Zhao, C Zhang, B Li, X Zhang, X Luo, C Zeng, W Li, M Gao, Y Dong Cellular and molecular bioengineering 11, 397-406, 2018 | 78 | 2018 |
Strategies for the CRISPR-based therapeutics B Li, Y Niu, W Ji, Y Dong Trends in pharmacological sciences 41 (1), 55-65, 2020 | 56 | 2020 |
Foxp1 is critical for the maintenance of regulatory T-cell homeostasis and suppressive function J Ren, L Han, J Tang, Y Liu, X Deng, Q Liu, P Hao, X Feng, B Li, H Hu, ... PLoS Biology 17 (5), e3000270, 2019 | 56 | 2019 |
Chemotherapy drugs derived nanoparticles encapsulating mRNA encoding tumor suppressor proteins to treat triple-negative breast cancer C Zhang, X Zhang, W Zhao, C Zeng, W Li, B Li, X Luo, J Li, J Jiang, ... Nano research 12, 855-861, 2019 | 51 | 2019 |
Effects of local structural transformation of lipid-like compounds on delivery of messenger RNA B Li, X Luo, B Deng, JLB Giancola, DW McComb, TD Schmittgen, Y Dong Scientific reports 6 (1), 22137, 2016 | 49 | 2016 |
Design and assessment of engineered CRISPR–Cpf1 and its use for genome editing B Li, C Zeng, Y Dong Nature protocols 13 (5), 899-914, 2018 | 46 | 2018 |
Prolyl 4-hydroxylase 2 promotes B-cell lymphoma progression via hydroxylation of Carabin W Jiang, X Zhou, Z Li, K Liu, W Wang, R Tan, X Cong, J Shan, Y Zhan, ... Blood, The Journal of the American Society of Hematology 131 (12), 1325-1336, 2018 | 35 | 2018 |
Dual-functional lipid-like nanoparticles for delivery of mRNA and MRI contrast agents X Luo, B Li, X Zhang, W Zhao, A Bratasz, B Deng, DW McComb, Y Dong Nanoscale 9 (4), 1575-1579, 2017 | 34 | 2017 |
Transketolase deficiency in adipose tissues protects mice from diet-induced obesity by promoting lipolysis N Tian, Q Liu, Y Li, L Tong, Y Lu, Y Zhu, P Zhang, H Chen, L Hu, J Meng, ... Diabetes 69 (7), 1355-1367, 2020 | 32 | 2020 |
Synthetic oligonucleotides inhibit CRISPR-Cpf1-mediated genome editing B Li, C Zeng, W Li, X Zhang, X Luo, W Zhao, C Zhang, Y Dong Cell reports 25 (12), 3262-3272. e3, 2018 | 32 | 2018 |
Molecular and biological role of the FOXP3 N-terminal domain in immune regulation by T regulatory/suppressor cells G Deng, Y Xiao, Z Zhou, Y Nagai, H Zhang, B Li, MI Greene Experimental and molecular pathology 93 (3), 334-338, 2012 | 32 | 2012 |
Secreted expression of mRNA‐encoded truncated ACE2 variants for SARS‐CoV‐2 via lipid‐like nanoassemblies M Li, S Li, Y Huang, H Chen, S Zhang, Z Zhang, W Wu, X Zeng, B Zhou, ... Advanced Materials 33 (34), 2101707, 2021 | 27 | 2021 |
CRISPR-Cas12a possesses unconventional DNase activity that can be inactivated by synthetic oligonucleotides B Li, J Yan, Y Zhang, W Li, C Zeng, W Zhao, X Hou, C Zhang, Y Dong Molecular Therapy-Nucleic Acids 19, 1043-1052, 2020 | 25 | 2020 |