KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice ES Polson, VB Kuchler, C Abbosh, EM Ross, RK Mathew, HA Beard, ... Science translational medicine 10 (454), eaar2718, 2018 | 71 | 2018 |
DogCatcher allows loop-friendly protein-protein ligation AH Keeble, VK Yadav, MP Ferla, CC Bauer, E Chuntharpursat-Bon, ... Cell chemical biology 29 (2), 339-350. e10, 2022 | 45 | 2022 |
Endothelial Piezo1 sustains muscle capillary density and contributes to physical activity F Bartoli, M Debant, E Chuntharpursat-Bon, EL Evans, KE Musialowski, ... The Journal of clinical investigation 132 (5), 2022 | 43 | 2022 |
PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing E Chuntharpursat-Bon, OV Povstyan, MJ Ludlow, DJ Carrier, M Debant, ... Communications Biology 6 (1), 358, 2023 | 39 | 2023 |
Potent, selective, and subunit‐dependent activation of TRPC5 channels by a xanthine derivative A Minard, CC Bauer, E Chuntharpursat‐Bon, IB Pickles, DJ Wright, ... British journal of pharmacology 176 (20), 3924-3938, 2019 | 36 | 2019 |
Improved PIEZO1 agonism through 4‐benzoic acid modification of Yoda1 G Parsonage, K Cuthbertson, N Endesh, N Murciano, AJ Hyman, ... British Journal of Pharmacology 180 (16), 2039-2063, 2023 | 25 | 2023 |
Kv1. 3 voltage-gated potassium channels link cellular respiration to proliferation through a non-conducting mechanism FL Styles, MM Al-Owais, JL Scragg, E Chuntharpursat-Bon, ... Cell death & disease 12 (4), 372, 2021 | 20 | 2021 |
Global PIEZO1 gain-of-function mutation causes cardiac hypertrophy and fibrosis in mice F Bartoli, EL Evans, NM Blythe, L Stewart, E Chuntharpursat-Bon, ... Cells 11 (7), 1199, 2022 | 15 | 2022 |
Xanthine-based photoaffinity probes allow assessment of ligand engagement by TRPC5 channels CC Bauer, A Minard, IB Pickles, KJ Simmons, E Chuntharpursat-Bon, ... RSC Chemical Biology 1 (5), 436-448, 2020 | 13 | 2020 |
Independent endothelial functions of PIEZO1 and TRPV4 in hepatic portal vein and predominance of PIEZO1 in mechanical and osmotic stress N Endesh, E Chuntharpursat‐Bon, C Revill, NY Yuldasheva, TS Futers, ... Liver International 43 (9), 2026-2038, 2023 | 9 | 2023 |
Cell adhesion molecule interaction with Piezo1 channels is a mechanism for sub cellular regulation of mechanical sensitivity E Chuntharpursat-Bon, OV Povstyan, MJ Ludlow, HJ Gaunt, PD Baxter, ... bioRxiv, 602532, 2019 | 9 | 2019 |
The small molecule KHS101 induces bioenergetic dysfunction in glioblastoma cells through inhibition of mitochondrial HSPD1 ES Polson, VB Kuchler, C Abbosh, EM Ross, RK Mathew, HA Beard, ... bioRxiv, 205203, 2017 | 2 | 2017 |
Endothelial force sensing signals to parenchymal cells to regulate bile and plasma lipids L Lichtenstein, CW Cheng, M Bajarwan, EL Evans, HJ Gaunt, F Bartoli, ... Science Advances 10 (39), eadq3075, 2024 | | 2024 |
Lipid regulatory effects of endothelial force sensing L Lichtenstein, C Cheng, E Evans, H Gaunt, F Bartoli, ... Atherosclerosis 395, 2024 | | 2024 |
PIEZO1 force sensing controls global lipid homeostasis L Lichtenstein, CW Cheng, EL Evans, HJ Gaunt, F Bartoli, ... bioRxiv, 2023.07. 23.550198, 2023 | | 2023 |
Using FRET to Determine How Myo10 Responds to Force in Filopodia F Parker, E Chuntharpursat-Bon, JE Molloy, M Peckham International Symposium of Mechanobiology, 67-77, 2022 | | 2022 |
Quantitative imaging of tyrosine kinase-drug interactions in cells. E Chuntharpursat | | 2012 |
The Influence of Ionic Strength on the Kinetics of Selected Enzymes E Chuntharpursat University of KwaZulu-Natal, Pietermaritzburg, 2005 | | 2005 |