Smoking-dependent reprogramming of alveolar macrophage polarization: implication for pathogenesis of chronic obstructive pulmonary disease R Shaykhiev, A Krause, J Salit, Y Strulovici-Barel, BG Harvey, ... The Journal of immunology 183 (4), 2867-2883, 2009 | 476 | 2009 |
Cilia dysfunction in lung disease AE Tilley, MS Walters, R Shaykhiev, RG Crystal Annual review of physiology 77 (1), 379-406, 2015 | 440 | 2015 |
Human endogenous antibiotic LL-37 stimulates airway epithelial cell proliferation and wound closure R Shaykhiev, C Beißwenger, K Kändler, J Senske, A Püchner, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 289 (5 …, 2005 | 345 | 2005 |
Cigarette smoking reprograms apical junctional complex molecular architecture in the human airway epithelium in vivo R Shaykhiev, F Otaki, P Bonsu, DT Dang, M Teater, Y Strulovici-Barel, ... Cellular and Molecular Life Sciences 68, 877-892, 2011 | 248 | 2011 |
At the root: defining and halting progression of early chronic obstructive pulmonary disease FJ Martinez, MLK Han, JP Allinson, RG Barr, RC Boucher, PMA Calverley, ... American journal of respiratory and critical care medicine 197 (12), 1540-1551, 2018 | 235 | 2018 |
The human airway epithelial basal cell transcriptome NR Hackett, R Shaykhiev, MS Walters, R Wang, RK Zwick, B Ferris, ... PloS one 6 (5), e18378, 2011 | 212 | 2011 |
The host defence peptide LL-37/hCAP-18 is a growth factor for lung cancer cells J von Haussen, R Koczulla, R Shaykhiev, C Herr, O Pinkenburg, ... Lung cancer 59 (1), 12-23, 2008 | 210 | 2008 |
Do Airway Epithelium Air–Liquid Cultures Represent the In Vivo Airway Epithelium Transcriptome? A Dvorak, AE Tilley, R Shaykhiev, R Wang, RG Crystal American journal of respiratory cell and molecular biology 44 (4), 465-473, 2011 | 208 | 2011 |
The role of cathelicidin and defensins in pulmonary inflammatory diseases C Herr, R Shaykhiev, R Bals Expert opinion on biological therapy 7 (9), 1449-1461, 2007 | 168 | 2007 |
The anti-microbial peptide LL-37 inhibits the activation of dendritic cells by TLR ligands K Kandler, R Shaykhiev, P Kleemann, F Klescz, M Lohoff, C Vogelmeier, ... International immunology 18 (12), 1729-1736, 2006 | 160 | 2006 |
RNA-Seq quantification of the human small airway epithelium transcriptome NR Hackett, MW Butler, R Shaykhiev, J Salit, L Omberg, ... BMC genomics 13, 1-31, 2012 | 137 | 2012 |
Early events in the pathogenesis of chronic obstructive pulmonary disease. Smoking-induced reprogramming of airway epithelial basal progenitor cells R Shaykhiev, RG Crystal Annals of the American Thoracic Society 11 (Supplement 5), S252-S258, 2014 | 129 | 2014 |
Interactions between epithelial cells and leukocytes in immunity and tissue homeostasis R Shaykhiev, R Bals Journal of Leucocyte Biology 82 (1), 1-15, 2007 | 122 | 2007 |
Innate immunity and chronic obstructive pulmonary disease: a mini-review R Shaykhiev, RG Crystal Gerontology 59 (6), 481-489, 2013 | 107 | 2013 |
Microbial patterns signaling via Toll-like receptors 2 and 5 contribute to epithelial repair, growth and survival R Shaykhiev, J Behr, R Bals PloS one 3 (1), e1393, 2008 | 107 | 2008 |
EGF shifts human airway basal cell fate toward a smoking-associated airway epithelial phenotype R Shaykhiev, WL Zuo, IW Chao, T Fukui, B Witover, A Brekman, ... Proceedings of the National Academy of Sciences 110 (29), 12102-12107, 2013 | 105 | 2013 |
Airway Basal stem/progenitor cells have diminished capacity to regenerate airway epithelium in chronic obstructive pulmonary disease MR Staudt, LJ Buro-Auriemma, MS Walters, J Salit, T Vincent, ... American journal of respiratory and critical care medicine 190 (8), 955-958, 2014 | 104 | 2014 |
Smoking dysregulates the human airway basal cell transcriptome at COPD risk locus 19q13. 2 DM Ryan, TL Vincent, J Salit, MS Walters, F Agosto-Perez, R Shaykhiev, ... PloS one 9 (2), e88051, 2014 | 87 | 2014 |
Smoking-dependent distal-to-proximal repatterning of the adult human small airway epithelium J Yang, WL Zuo, T Fukui, IW Chao, K Gomi, B Lee, MR Staudt, RJ Kaner, ... American journal of respiratory and critical care medicine 196 (3), 340-352, 2017 | 85 | 2017 |
EGF-amphiregulin interplay in airway stem/progenitor cells links the pathogenesis of smoking-induced lesions in the human airway epithelium WL Zuo, J Yang, K Gomi, IW Chao, RG Crystal, R Shaykhiev Stem Cells 35 (3), 824-837, 2017 | 67 | 2017 |