| Suppression of aging in mice by the hormone Klotho H Kurosu, M Yamamoto, JD Clark, JV Pastor, A Nandi, P Gurnani, ... Science 309 (5742), 1829-1833, 2005 | 2093 | 2005 |
| Osteoarthritis development in novel experimental mouse models induced by knee joint instability S Kamekura, K Hoshi, T Shimoaka, U Chung, H Chikuda, T Yamada, ... Osteoarthritis and cartilage 13 (7), 632-641, 2005 | 647 | 2005 |
| Contribution of runt‐related transcription factor 2 to the pathogenesis of osteoarthritis in mice after induction of knee joint instability S Kamekura, Y Kawasaki, K Hoshi, T Shimoaka, H Chikuda, Z Maruyama, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2006 | 359 | 2006 |
| Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim T Akiyama, P Bouillet, T Miyazaki, Y Kadono, H Chikuda, U Chung, ... The EMBO journal 22 (24), 6653-6664, 2003 | 317 | 2003 |
| Connection between B lymphocyte and osteoclast differentiation pathways N Manabe, H Kawaguchi, H Chikuda, C Miyaura, M Inada, R Nagai, ... The Journal of Immunology 167 (5), 2625-2631, 2001 | 267 | 2001 |
| Independent impairment of osteoblast and osteoclast differentiation in klotho mouse exhibiting low-turnover osteopenia H Kawaguchi, N Manabe, C Miyaura, H Chikuda, K Nakamura, M Kuro-o The Journal of clinical investigation 104 (3), 229-237, 1999 | 250 | 1999 |
| Comparison of the Japanese Orthopaedic Association (JOA) score and modified JOA (mJOA) score for the assessment of cervical myelopathy: a multicenter observational study S Kato, Y Oshima, H Oka, H Chikuda, Y Takeshita, K Miyoshi, ... PloS one 10 (4), e0123022, 2015 | 235 | 2015 |
| Incidence and risk factors for mortality of vertebral osteomyelitis: a retrospective analysis using the Japanese diagnosis procedure combination database T Akiyama, H Chikuda, H Yasunaga, H Horiguchi, K Fushimi, K Saita BMJ open 3 (3), e002412, 2013 | 207 | 2013 |
| Involvement of endogenous bone morphogenetic protein (BMP) 2 and BMP6 in bone formation F Kugimiya, H Kawaguchi, S Kamekura, H Chikuda, S Ohba, F Yano, ... Journal of Biological Chemistry 280 (42), 35704-35712, 2005 | 189 | 2005 |
| The canonical Wnt signaling pathway promotes chondrocyte differentiation in a Sox9-dependent manner F Yano, F Kugimiya, S Ohba, T Ikeda, H Chikuda, T Ogasawara, N Ogata, ... Biochemical and biophysical research communications 333 (4), 1300-1308, 2005 | 175 | 2005 |
| GSK-3β controls osteogenesis through regulating Runx2 activity F Kugimiya, H Kawaguchi, S Ohba, N Kawamura, M Hirata, H Chikuda, ... PloS one 2 (9), e837, 2007 | 174 | 2007 |
| Cyclic GMP-dependent protein kinase II is a molecular switch from proliferation to hypertrophic differentiation of chondrocytes H Chikuda, F Kugimiya, K Hoshi, T Ikeda, T Ogasawara, T Shimoaka, ... Genes & Development 18 (19), 2418-2429, 2004 | 162 | 2004 |
| The normative score and the cut-off value of the Oswestry Disability Index (ODI) J Tonosu, K Takeshita, N Hara, K Matsudaira, S Kato, K Masuda, ... European Spine Journal 21, 1596-1602, 2012 | 155 | 2012 |
| Regulation of multiple ageing-like phenotypes by inducible klotho gene expression in klotho mutant mice H Masuda, H Chikuda, T Suga, H Kawaguchi, M Kuro-o Mechanisms of ageing and development 126 (12), 1274-1283, 2005 | 148 | 2005 |
| Mortality and morbidity after high-dose methylprednisolone treatment in patients with acute cervical spinal cord injury: a propensity-matched analysis using a nationwide … H Chikuda, H Yasunaga, K Takeshita, H Horiguchi, H Kawaguchi, K Ohe, ... Emergency Medicine Journal 31 (3), 201-206, 2014 | 130 | 2014 |
| Natural course and prognostic factors in patients with mild cervical spondylotic myelopathy with increased signal intensity on T2-weighted magnetic resonance imaging Y Oshima, A Seichi, K Takeshita, H Chikuda, T Ono, S Baba, J Morii, ... Spine 37 (22), 1909-1913, 2012 | 115 | 2012 |
| Radiographic analysis of the cervical spine in patients with retro-odontoid pseudotumors H Chikuda, A Seichi, K Takeshita, N Shoda, T Ono, K Matsudaira, ... Spine 34 (3), E110-E114, 2009 | 108 | 2009 |
| Phosphorylation of GSK-3β by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes Y Kawasaki, F Kugimiya, H Chikuda, S Kamekura, T Ikeda, N Kawamura, ... The Journal of clinical investigation 118 (7), 2506-2515, 2008 | 98 | 2008 |
| Transcription factor Hes1 modulates osteoarthritis development in cooperation with calcium/calmodulin-dependent protein kinase 2 S Sugita, Y Hosaka, K Okada, D Mori, F Yano, H Kobayashi, Y Taniguchi, ... Proceedings of the National Academy of Sciences 112 (10), 3080-3085, 2015 | 96 | 2015 |
| A novel disease-modifying osteoarthritis drug candidate targeting Runx1 F Yano, H Hojo, S Ohba, A Fukai, Y Hosaka, T Ikeda, T Saito, M Hirata, ... Annals of the rheumatic diseases 72 (5), 748-753, 2013 | 94 | 2013 |
Ung-il ChungUniversity of Tokyo Schools of Engineering and Medicine; Kanagawa University of Human Services在 tetrapod.t.u-tokyo.ac.jp 的电子邮件经过验证
