Genomic instability and aging-like phenotype in the absence of mammalian SIRT6 R Mostoslavsky, KF Chua, DB Lombard, WW Pang, MR Fischer, L Gellon, ... Cell 124 (2), 315-329, 2006 | 1852 | 2006 |
Toward a unified nomenclature for mammalian ADP-ribosyltransferases MO Hottiger, PO Hassa, B Lüscher, H Schüler, F Koch-Nolte Trends in biochemical sciences 35 (4), 208-219, 2010 | 951 | 2010 |
Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going? PO Hassa, SS Haenni, M Elser, MO Hottiger Microbiology and Molecular Biology Reviews 70 (3), 789-829, 2006 | 920 | 2006 |
p53 inhibition by the LANA protein of KSHV protects against cell death J Friborg Jr, W Kong, MO Hottiger, GJ Nabel Nature 402 (6764), 889-894, 1999 | 856 | 1999 |
The diverse biological roles of mammalian PARPS, a small but powerful family of poly-ADP-ribose polymerases PO Hassa, MO Hottiger Frontiers in Bioscience (Landmark Edition) 13, 3046-3082, 2008 | 723 | 2008 |
Crosstalk between Wnt/β-Catenin and NF-κB signaling pathway during inflammation B Ma, MO Hottiger Frontiers in immunology 7, 221254, 2016 | 572 | 2016 |
The functional role of poly (ADP-ribose) polymerase 1 as novel coactivator of NF-κB in inflammatory disorders PO Hassa, MO Hottiger Cellular and Molecular Life Sciences CMLS 59, 1534-1553, 2002 | 506 | 2002 |
A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation G Timinszky, S Till, PO Hassa, M Hothorn, G Kustatscher, B Nijmeijer, ... Nature structural & molecular biology 16 (9), 923-929, 2009 | 491 | 2009 |
Molecular mechanism of poly (ADP-ribosyl) ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites M Altmeyer, S Messner, PO Hassa, M Fey, MO Hottiger Nucleic acids research 37 (11), 3723-3738, 2009 | 446 | 2009 |
Poly (ADP-ribose) polymerase 1 participates in the phase entrainment of circadian clocks to feeding G Asher, H Reinke, M Altmeyer, M Gutierrez-Arcelus, MO Hottiger, ... Cell 142 (6), 943-953, 2010 | 416 | 2010 |
SIRT2 regulates NF-κB-dependent gene expression through deacetylation of p65 Lys310 KM Rothgiesser, S Erener, S Waibel, B Lüscher, MO Hottiger Journal of cell science 123 (24), 4251-4258, 2010 | 413 | 2010 |
Proteome-wide identification of poly (ADP-Ribosyl) ation targets in different genotoxic stress responses S Jungmichel, F Rosenthal, M Altmeyer, J Lukas, MO Hottiger, ML Nielsen Molecular cell 52 (2), 272-285, 2013 | 399 | 2013 |
Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation H Kleine, E Poreba, K Lesniewicz, PO Hassa, MO Hottiger, DW Litchfield, ... Molecular cell 32 (1), 57-69, 2008 | 394 | 2008 |
A role of poly (ADP-ribose) polymerase in NF-B transcriptional activation PO Hassa, MO Hottiger Walter de Gruyter 380 (7-8), 953-959, 1999 | 394 | 1999 |
The enzymatic and DNA binding activity of PARP-1 are not required for NF-κB coactivator function PO Hassa, M Covic, S Hasan, R Imhof, MO Hottiger Journal of Biological Chemistry 276 (49), 45588-45597, 2001 | 379 | 2001 |
Acetylation of poly (ADP-ribose) polymerase-1 by p300/CREB-binding protein regulates coactivation of NF-κB-dependent transcription PO Hassa, SS Haenni, C Buerki, NI Meier, WS Lane, H Owen, ... Journal of biological chemistry 280 (49), 40450-40464, 2005 | 376 | 2005 |
Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases F Rosenthal, KLH Feijs, E Frugier, M Bonalli, AH Forst, R Imhof, ... Nature structural & molecular biology 20 (4), 502-507, 2013 | 351 | 2013 |
SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly (ADP-ribose) polymerase 1 SB Rajamohan, VB Pillai, M Gupta, NR Sundaresan, KG Birukov, ... Molecular and cellular biology 29 (15), 4116-4129, 2009 | 348 | 2009 |
Carcinogenic bacterial pathogen Helicobacter pylori triggers DNA double-strand breaks and a DNA damage response in its host cells IM Toller, KJ Neelsen, M Steger, ML Hartung, MO Hottiger, M Stucki, ... Proceedings of the National Academy of Sciences 108 (36), 14944-14949, 2011 | 346 | 2011 |
PARP1 ADP-ribosylates lysine residues of the core histone tails S Messner, M Altmeyer, H Zhao, A Pozivil, B Roschitzki, P Gehrig, ... Nucleic acids research 38 (19), 6350-6362, 2010 | 327 | 2010 |