Coordination of metabolic plasticity in skeletal muscle DA Hood, I Irrcher, V Ljubicic, AM Joseph Journal of experimental biology 209 (12), 2265-2275, 2006 | 493 | 2006 |
Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics I Irrcher, H Aleyasin, EL Seifert, SJ Hewitt, S Chhabra, M Phillips, AK Lutz, ... Human molecular genetics 19 (19), 3734-3746, 2010 | 462 | 2010 |
Interactions between ROS and AMP kinase activity in the regulation of PGC-1α transcription in skeletal muscle cells I Irrcher, V Ljubicic, DA Hood American Journal of Physiology-Cell Physiology 296 (1), C116-C123, 2009 | 458 | 2009 |
PPARγ coactivator-1α expression during thyroid hormone-and contractile activity-induced mitochondrial adaptations I Irrcher, PJ Adhihetty, T Sheehan, AM Joseph, DA Hood American Journal of Physiology-Cell Physiology 284 (6), C1669-C1677, 2003 | 424 | 2003 |
Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress L Bouman, A Schlierf, AK Lutz, J Shan, A Deinlein, J Kast, Z Galehdar, ... Cell Death & Differentiation 18 (5), 769-782, 2011 | 384 | 2011 |
Regulation of mitochondrial biogenesis in muscle by endurance exercise I Irrcher, PJ Adhihetty, AM Joseph, V Ljubicic, DA Hood Sports medicine 33, 783-793, 2003 | 281 | 2003 |
AMP-activated protein kinase-regulated activation of the PGC-1α promoter in skeletal muscle cells I Irrcher, V Ljubicic, AF Kirwan, DA Hood PloS one 3 (10), e3614, 2008 | 270 | 2008 |
Plasticity of skeletal muscle mitochondria in response to contractile activity PJ Adhihetty, I Irrcher, AM Joseph, V Ljubicic, DA Hood Experimental physiology 88 (1), 99-107, 2003 | 260 | 2003 |
DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway H Aleyasin, MWC Rousseaux, PC Marcogliese, SJ Hewitt, I Irrcher, ... Proceedings of the National Academy of Sciences 107 (7), 3186-3191, 2010 | 201 | 2010 |
Thyroid hormone (T3) rapidly activates p38 and AMPK in skeletal muscle in vivo I Irrcher, DR Walkinshaw, TE Sheehan, DA Hood Journal of applied physiology 104 (1), 178-185, 2008 | 94 | 2008 |
Mitochondrial biogenesis and the role of the protein import pathway. DA Hood, PJ Adhihetty, M Colavecchia, JW Gordon, I Irrcher, AM Joseph, ... Medicine and science in sports and exercise 35 (1), 86-94, 2003 | 92 | 2003 |
CDK5 phosphorylates DRP1 and drives mitochondrial defects in NMDA-induced neuronal death A Jahani-Asl, E Huang, I Irrcher, J Rashidian, N Ishihara, DC Lagace, ... Human molecular genetics 24 (16), 4573-4583, 2015 | 91 | 2015 |
Contractile activity-induced transcriptional activation of cytochrome C involves Sp1 and is proportional to mitochondrial ATP synthesis in C2C12 muscle cells MK Connor, I Irrcher, DA Hood Journal of Biological Chemistry 276 (19), 15898-15904, 2001 | 89 | 2001 |
Calcium-regulated changes in mitochondrial phenotype in skeletal muscle cells D Freyssenet, I Irrcher, MK Connor, M Di Carlo, DA Hood American Journal of Physiology-Cell Physiology 286 (5), C1053-C1061, 2004 | 82 | 2004 |
Multiple signaling pathways regulate contractile activity‐mediated PGC‐1α gene expression and activity in skeletal muscle cells Y Zhang, G Uguccioni, V Ljubicic, I Irrcher, S Iqbal, K Singh, S Ding, ... Physiological reports 2 (5), e12008, 2014 | 79 | 2014 |
Regulation of Egr-1, SRF, and Sp1 mRNA expression in contracting skeletal muscle cells I Irrcher, DA Hood Journal of applied physiology 97 (6), 2207-2213, 2004 | 60 | 2004 |
DJ-1 interacts with and regulates paraoxonase-2, an enzyme critical for neuronal survival in response to oxidative stress M Parsanejad, N Bourquard, D Qu, Y Zhang, E Huang, MWC Rousseaux, ... PLoS One 9 (9), e106601, 2014 | 54 | 2014 |
Regulation of the VHL/HIF-1 pathway by DJ-1 M Parsanejad, Y Zhang, D Qu, I Irrcher, MWC Rousseaux, H Aleyasin, ... Journal of Neuroscience 34 (23), 8043-8050, 2014 | 52 | 2014 |
Parkinson’s disease: to live or die by autophagy I Irrcher, DS Park Science signaling 2 (65), pe21-pe21, 2009 | 27 | 2009 |
Mitochondrial biogenesis induced by endurance training DA Hood, I Irrcher ACSM’s Advanced Exercise Physiology, 437-452, 2006 | 8 | 2006 |