Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis R Romero, VI Sayin, SM Davidson, MR Bauer, SX Singh, SE LeBoeuf, ... Nature medicine 23 (11), 1362-1368, 2017 | 592 | 2017 |
Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer VI Sayin, SE LeBoeuf, SX Singh, SM Davidson, D Biancur, BS Guzelhan, ... Elife 6, e28083, 2017 | 212 | 2017 |
Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events A Ashouri, VI Sayin, J Van den Eynden, SX Singh, T Papagiannakopoulos, ... Nature communications 7 (1), 13197, 2016 | 59 | 2016 |
MTAP loss promotes stemness in glioblastoma and confers unique susceptibility to purine starvation LJ Hansen, R Sun, R Yang, SX Singh, LH Chen, CJ Pirozzi, CJ Moure, ... Cancer research 79 (13), 3383-3394, 2019 | 40 | 2019 |
A PRMT5-RNF168-SMURF2 axis controls h2ax proteostasis C Du, LJ Hansen, SX Singh, F Wang, R Sun, CJ Moure, K Roso, PK Greer, ... Cell reports 28 (12), 3199-3211. e5, 2019 | 39 | 2019 |
Glial progenitor heterogeneity and key regulators revealed by single-cell RNA sequencing provide insight to regeneration in spinal cord injury H Wei, X Wu, J Withrow, RCD Duran, S Singh, LS Chaboub, J Rakshit, ... Cell reports 42 (5), 2023 | 16 | 2023 |
Epigenetic regulation of fanconi anemia genes implicates PRMT5 blockage as a strategy for tumor chemosensitization C Du, SW Li, SX Singh, K Roso, MA Sun, CJ Pirozzi, R Yang, JL Li, Y He Molecular Cancer Research 19 (12), 2046-2056, 2022 | 9 | 2022 |
Purine synthesis inhibitor L-alanosine impairs mitochondrial function and stemness of brain tumor initiating cells SX Singh, R Yang, K Roso, LJ Hansen, C Du, LH Chen, PK Greer, ... Biomedicines 10 (4), 751, 2022 | 7 | 2022 |
Inhibiting adenine synthesis attenuates glioblastoma cell stemness and temozolomide resistance SX Singh, R Yang, K Roso, LJ Hansen, C Du, LH Chen, PK Greer, ... bioRxiv, 2021.06. 21.449341, 2021 | 1 | 2021 |
Treating MTAP-Deficient Brain Tumors with Purine Synthesis Inhibition S Singh Duke University, 2022 | | 2022 |