关注
Simranjit X. Singh
Simranjit X. Singh
Department of Pathology, Duke University School of Medicine
在 duke.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis
R Romero, VI Sayin, SM Davidson, MR Bauer, SX Singh, SE LeBoeuf, ...
Nature medicine 23 (11), 1362-1368, 2017
5922017
Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer
VI Sayin, SE LeBoeuf, SX Singh, SM Davidson, D Biancur, BS Guzelhan, ...
Elife 6, e28083, 2017
2122017
Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events
A Ashouri, VI Sayin, J Van den Eynden, SX Singh, T Papagiannakopoulos, ...
Nature communications 7 (1), 13197, 2016
592016
MTAP loss promotes stemness in glioblastoma and confers unique susceptibility to purine starvation
LJ Hansen, R Sun, R Yang, SX Singh, LH Chen, CJ Pirozzi, CJ Moure, ...
Cancer research 79 (13), 3383-3394, 2019
402019
A PRMT5-RNF168-SMURF2 axis controls h2ax proteostasis
C Du, LJ Hansen, SX Singh, F Wang, R Sun, CJ Moure, K Roso, PK Greer, ...
Cell reports 28 (12), 3199-3211. e5, 2019
392019
Glial progenitor heterogeneity and key regulators revealed by single-cell RNA sequencing provide insight to regeneration in spinal cord injury
H Wei, X Wu, J Withrow, RCD Duran, S Singh, LS Chaboub, J Rakshit, ...
Cell reports 42 (5), 2023
162023
Epigenetic regulation of fanconi anemia genes implicates PRMT5 blockage as a strategy for tumor chemosensitization
C Du, SW Li, SX Singh, K Roso, MA Sun, CJ Pirozzi, R Yang, JL Li, Y He
Molecular Cancer Research 19 (12), 2046-2056, 2022
92022
Purine synthesis inhibitor L-alanosine impairs mitochondrial function and stemness of brain tumor initiating cells
SX Singh, R Yang, K Roso, LJ Hansen, C Du, LH Chen, PK Greer, ...
Biomedicines 10 (4), 751, 2022
72022
Inhibiting adenine synthesis attenuates glioblastoma cell stemness and temozolomide resistance
SX Singh, R Yang, K Roso, LJ Hansen, C Du, LH Chen, PK Greer, ...
bioRxiv, 2021.06. 21.449341, 2021
12021
Treating MTAP-Deficient Brain Tumors with Purine Synthesis Inhibition
S Singh
Duke University, 2022
2022
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