A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma DM O’Rourke, MLP Nasrallah, A Desai, JJ Melenhorst, K Mansfield, ... Science translational medicine 9 (399), eaaa0984, 2017 | 1538 | 2017 |
A patient-derived glioblastoma organoid model and biobank recapitulates inter-and intra-tumoral heterogeneity F Jacob, RD Salinas, DY Zhang, PTT Nguyen, JG Schnoll, SZH Wong, ... Cell 180 (1), 188-204. e22, 2020 | 680 | 2020 |
Glioma progression is shaped by genetic evolution and microenvironment interactions FS Varn, KC Johnson, J Martinek, JT Huse, MLP Nasrallah, P Wesseling, ... Cell 185 (12), 2184-2199. e16, 2022 | 210 | 2022 |
Radiomic MRI signature reveals three distinct subtypes of glioblastoma with different clinical and molecular characteristics, offering prognostic value beyond IDH1 S Rathore, H Akbari, M Rozycki, KG Abdullah, MLP Nasrallah, ZA Binder, ... Scientific reports 8 (1), 5087, 2018 | 168 | 2018 |
Epidermal growth factor receptor extracellular domain mutations in glioblastoma present opportunities for clinical imaging and therapeutic development ZA Binder, AH Thorne, S Bakas, EP Wileyto, M Bilello, H Akbari, ... Cancer cell 34 (1), 163-177. e7, 2018 | 161 | 2018 |
In vivo evaluation of EGFRvIII mutation in primary glioblastoma patients via complex multiparametric MRI signature H Akbari, S Bakas, JM Pisapia, MLP Nasrallah, M Rozycki, ... Neuro-oncology 20 (8), 1068-1079, 2018 | 108 | 2018 |
Molecular and clinicopathologic features of gliomas harboring NTRK fusions M Torre, V Vasudevaraja, J Serrano, M DeLorenzo, S Malinowski, ... Acta Neuropathologica Communications 8, 1-14, 2020 | 100 | 2020 |
The second window ICG technique demonstrates a broad plateau period for near infrared fluorescence tumor contrast in glioblastoma R Zeh, S Sheikh, L Xia, J Pierce, A Newton, J Predina, S Cho, ... PLoS One 12 (7), e0182034, 2017 | 92 | 2017 |
Clinical utility of plasma cell-free DNA in adult patients with newly diagnosed glioblastoma: a pilot prospective study SJ Bagley, SA Nabavizadeh, JJ Mays, JE Till, JB Ware, S Levy, ... Clinical Cancer Research 26 (2), 397-407, 2020 | 89 | 2020 |
Histopathology‐validated machine learning radiographic biomarker for noninvasive discrimination between true progression and pseudo‐progression in glioblastoma H Akbari, S Rathore, S Bakas, MLP Nasrallah, G Shukla, E Mamourian, ... Cancer 126 (11), 2625-2636, 2020 | 77 | 2020 |
Anti-MOG encephalitis mimicking small vessel CNS vasculitis K Patterson, E Iglesias, M Nasrallah, V González-Álvarez, M Suñol, ... Neurology: Neuroimmunology & Neuroinflammation 6 (2), e538, 2019 | 71 | 2019 |
Non-invasive detection of 2-hydroxyglutarate in IDH-mutated gliomas using two-dimensional localized correlation spectroscopy (2D L-COSY) at 7 Tesla G Verma, S Mohan, MLP Nasrallah, S Brem, JYK Lee, S Chawla, S Wang, ... Journal of translational medicine 14, 1-8, 2016 | 53 | 2016 |
The University of Pennsylvania glioblastoma (UPenn-GBM) cohort: advanced MRI, clinical, genomics, & radiomics S Bakas, C Sako, H Akbari, M Bilello, A Sotiras, G Shukla, JD Rudie, ... Scientific data 9 (1), 453, 2022 | 50 | 2022 |
Developmental interneuron subtype deficits after targeted loss of Arx ED Marsh, MLP Nasrallah, C Walsh, KA Murray, C Nicole Sunnen, ... BMC neuroscience 17, 1-16, 2016 | 50 | 2016 |
Differential effects of a polyalanine tract expansion in Arx on neural development and gene expression MLP Nasrallah, G Cho, JC Simonet, ME Putt, K Kitamura, JA Golden Human molecular genetics 21 (5), 1090-1098, 2012 | 47 | 2012 |
Clinical activity of the EGFR tyrosine kinase inhibitor osimertinib in EGFR-mutant glioblastoma I Makhlin, RD Salinas, D Zhang, F Jacob, G Ming, H Song, D Saxena, ... CNS oncology 8 (3), CNS43, 2019 | 46 | 2019 |
Case report: prolonged survival following EGFRvIII CAR T cell treatment for recurrent glioblastoma JS Durgin, F Henderson Jr, MLP Nasrallah, S Mohan, S Wang, SF Lacey, ... Frontiers in Oncology 11, 669071, 2021 | 44 | 2021 |
AI-based prognostic imaging biomarkers for precision neuro-oncology: the ReSPOND consortium C Davatzikos, JS Barnholtz-Sloan, S Bakas, R Colen, A Mahajan, ... Neuro-oncology 22 (6), 886-888, 2020 | 43 | 2020 |
Three‐dimensional echo planar spectroscopic imaging for differentiation of true progression from pseudoprogression in patients with glioblastoma G Verma, S Chawla, S Mohan, S Wang, ML Nasrallah, S Sheriff, A Desai, ... NMR in Biomedicine 32 (2), e4042, 2019 | 43 | 2019 |
Locally secreted BiTEs complement CAR T cells by enhancing killing of antigen heterogeneous solid tumors Y Yin, JL Rodriguez, N Li, R Thokala, MLP Nasrallah, L Hu, L Zhang, ... Molecular Therapy 30 (7), 2537-2553, 2022 | 42 | 2022 |