Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis S Turajlic, K Litchfield, H Xu, R Rosenthal, N McGranahan, JL Reading, ... The lancet oncology 18 (8), 1009-1021, 2017 | 870 | 2017 |
Neoantigen-directed immune escape in lung cancer evolution R Rosenthal, EL Cadieux, R Salgado, MA Bakir, DA Moore, CT Hiley, ... Nature 567 (7749), 479-485, 2019 | 746 | 2019 |
Meta-analysis of tumor-and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition K Litchfield, JL Reading, C Puttick, K Thakkar, C Abbosh, R Bentham, ... Cell 184 (3), 596-614. e14, 2021 | 589 | 2021 |
Fc effector function contributes to the activity of human anti-CTLA-4 antibodies FA Vargas, AJS Furness, K Litchfield, K Joshi, R Rosenthal, E Ghorani, ... Cancer cell 33 (4), 649-663. e4, 2018 | 546 | 2018 |
Lung adenocarcinoma promotion by air pollutants W Hill, EL Lim, CE Weeden, C Lee, M Augustine, K Chen, FC Kuan, ... Nature 616 (7955), 159-167, 2023 | 238 | 2023 |
Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer K Joshi, MR de Massy, M Ismail, JL Reading, I Uddin, A Woolston, ... Nature medicine 25 (10), 1549-1559, 2019 | 171 | 2019 |
The function and dysfunction of memory CD8+ T cells in tumor immunity JL Reading, F Gálvez‐Cancino, C Swanton, A Lladser, KS Peggs, ... Immunological reviews 283 (1), 194-212, 2018 | 162 | 2018 |
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma L Au, E Hatipoglu, MR de Massy, K Litchfield, G Beattie, A Rowan, ... Cancer cell 39 (11), 1497-1518. e11, 2021 | 161 | 2021 |
Differential binding affinity of mutated peptides for MHC class I is a predictor of survival in advanced lung cancer and melanoma E Ghorani, R Rosenthal, N McGranahan, JL Reading, M Lynch, KS Peggs, ... Annals of oncology 29 (1), 271-279, 2018 | 124 | 2018 |
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA C Abbosh, AM Frankell, T Harrison, J Kisistok, A Garnett, L Johnson, ... Nature 616 (7957), 553-562, 2023 | 105 | 2023 |
Mesenchymal stem cells in solid organ transplantation (MiSOT) fourth meeting: lessons learned from first clinical trials M Franquesa, MJ Hoogduijn, ME Reinders, E Eggenhofer, AU Engela, ... Transplantation 96 (3), 234-238, 2013 | 100 | 2013 |
The evolution of lung cancer and impact of subclonal selection in TRACERx AM Frankell, M Dietzen, M Al Bakir, EL Lim, T Karasaki, S Ward, ... Nature 616 (7957), 525-533, 2023 | 97 | 2023 |
Tracking cancer evolution through the disease course C Bailey, JRM Black, JL Reading, K Litchfield, S Turajlic, N McGranahan, ... Cancer discovery 11 (4), 916-932, 2021 | 97 | 2021 |
Antibodies against endogenous retroviruses promote lung cancer immunotherapy KW Ng, J Boumelha, KSS Enfield, J Almagro, H Cha, O Pich, T Karasaki, ... Nature 616 (7957), 563-573, 2023 | 90 | 2023 |
The T cell differentiation landscape is shaped by tumour mutations in lung cancer E Ghorani, JL Reading, JY Henry, MR Massy, R Rosenthal, V Turati, ... Nature cancer 1 (5), 546-561, 2020 | 87 | 2020 |
Clinical-grade multipotent adult progenitor cells durably control pathogenic T cell responses in human models of transplantation and autoimmunity JL Reading, JHM Yang, S Sabbah, A Skowera, RR Knight, J Pinxteren, ... The Journal of Immunology 190 (9), 4542-4552, 2013 | 87 | 2013 |
Escape from nonsense-mediated decay associates with anti-tumor immunogenicity K Litchfield, JL Reading, EL Lim, H Xu, P Liu, M Al-Bakir, YNS Wong, ... Nature communications 11 (1), 3800, 2020 | 78 | 2020 |
Natural variation in interleukin-2 sensitivity influences regulatory T-cell frequency and function in individuals with long-standing type 1 diabetes JHM Yang, AJ Cutler, RC Ferreira, JL Reading, NJ Cooper, C Wallace, ... Diabetes 64 (11), 3891-3902, 2015 | 68 | 2015 |
The evolution of non-small cell lung cancer metastases in TRACERx M Al Bakir, A Huebner, C Martínez-Ruiz, K Grigoriadis, TBK Watkins, ... Nature 616 (7957), 534-542, 2023 | 66 | 2023 |
Neoantigen-specific CD8 T cell responses in the peripheral blood following PD-L1 blockade might predict therapy outcome in metastatic urothelial carcinoma JS Holm, SA Funt, A Borch, KK Munk, AM Bjerregaard, JL Reading, ... Nature communications 13 (1), 1935, 2022 | 56 | 2022 |