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Yongxian Zhuang
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引用次数
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Cell cycle arrest in Metformin treated breast cancer cells involves activation of AMPK, downregulation of cyclin D1, and requires p27Kip1 or p21Cip1
Y Zhuang, WK Miskimins
Journal of molecular signaling 3, 1-11, 2008
3662008
DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine
J Yu, BO Qin, AM Moyer, S Nowsheen, T Liu, S Qin, Y Zhuang, D Liu, ...
The Journal of clinical investigation 128 (6), 2376-2388, 2018
1712018
Mechanisms by which low glucose enhances the cytotoxicity of metformin to cancer cells both in vitro and in vivo
Y Zhuang, DK Chan, AB Haugrud, WK Miskimins
PloS one 9 (9), e108444, 2014
1582014
Metformin induces both caspase-dependent and poly (ADP-ribose) polymerase-dependent cell death in breast cancer cells
Y Zhuang, WK Miskimins
Molecular Cancer Research 9 (5), 603-615, 2011
1472011
Dichloroacetate enhances apoptotic cell death via oxidative damage and attenuates lactate production in metformin-treated breast cancer cells
AB Haugrud, Y Zhuang, JD Coppock, WK Miskimins
Breast cancer research and treatment 147, 539-550, 2014
1262014
ERICH3: vesicular association and antidepressant treatment response
D Liu, Y Zhuang, L Zhang, H Gao, D Neavin, T Carrillo-Roa, Y Wang, J Yu, ...
Molecular psychiatry 26 (6), 2415-2428, 2021
272021
The novel function of tumor protein D54 in regulating pyruvate dehydrogenase and metformin cytotoxicity in breast cancer
Y Zhuang, RC Ly, CV Frazier, J Yu, S Qin, XY Fan, MP Goetz, ...
Cancer & metabolism 7, 1-15, 2019
172019
NDUFA4L2 promotes trastuzumab resistance in HER2-positive breast cancer
Y Yuan, H Gao, Y Zhuang, L Wei, J Yu, Z Zhang, L Zhang, L Wang
Therapeutic advances in medical oncology 13, 17588359211027836, 2021
142021
Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome‐Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2
TM Dudenkov, D Liu, J Cairns, S Devarajan, Y Zhuang, JN Ingle, ...
Clinical Pharmacology & Therapeutics 106 (1), 219-227, 2019
122019
Identification of Src family kinases as potential therapeutic targets for chemotherapy-resistant triple negative breast cancer
IN Kohale, J Yu, Y Zhuang, X Fan, RJ Reddy, J Sinnwell, KR Kalari, ...
Cancers 14 (17), 4220, 2022
92022
Use of Antimetastatic SOD3‐Mimetic Albumin as a Primer in Triple Negative Breast Cancer
SM Messerli, AM Schaefer, Y Zhuang, BJ Soltys, N Keime, J Jin, L Ma, ...
Journal of Oncology 2019 (1), 3253696, 2019
92019
Biomarkers for predicting abiraterone treatment outcome and selecting alternative therapies in castration‐resistant prostate cancer
S Qin, H Gao, W Kim, H Zhang, Y Gu, KR Kalari, JP Sinnwell, JA Scholz, ...
Clinical Pharmacology & Therapeutics 111 (6), 1296-1306, 2022
82022
Oncolytic Urabe mumps virus: A promising virotherapy for triple-negative breast cancer
MD Behrens, RJ Stiles, GM Pike, LA Sikkink, Y Zhuang, J Yu, L Wang, ...
Molecular Therapy-Oncolytics 27, 239-255, 2022
72022
Establishment and characterization of immortalized human breast cancer cell lines from breast cancer patient-derived xenografts (PDX)
Y Zhuang, JM Grainger, PT Vedell, J Yu, AM Moyer, H Gao, XY Fan, S Qin, ...
NPJ Breast Cancer 7 (1), 79, 2021
72021
A genome-wide association study in human lymphoblastoid cells supports safety of mitochondrial complex I inhibitor
H Gao, U Tripathi, S Trushin, L Okromelidze, NP Pichurin, L Wei, ...
Mitochondrion 58, 83-94, 2021
72021
Preventing feedback activation of glycolytic ATP production enhances metformin cytotoxicity in breast cancer cells when oxidative phosphorylation is inhibited
Y Zhuang, DK Chan, WK Miskimins
Cancer & Metabolism 2, 1-2, 2014
22014
Mechanisms by Which Low Glucose Enhances the Cytotoxicity of Metformin to Cancer Cells Both
Y Zhuang, DK Chan, AB Haugrud, WK Miskimins
Vitro, 2014
22014
Ability of metformin to deplete NAD+ contributes to cancer cell susceptibility to metformin cytotoxicity and is dependent on NAMPT expression
Y Zhuang, AB Haugrud, MA Schaefer, SM Messerli, WK Miskimins
Frontiers in Oncology 13, 1225220, 2023
12023
HPV+ cancer cell lactate production attenuates immune response during treatment: lactate production inhibition leads to improved long-term cures
Y Zhuang, D Vermeer, Y Jung, A Haugrud, J Lee, WK
Infectious Agents and Cancer 7 (Suppl 1), p35, 2012
1*2012
Metformin inhibits breast cancer cell proliferation by downregulating cyclin D1
Y Zhuang, WK Miskimins
CANCER RESEARCH 66 (8), 2006
12006
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