| Katanin contributes to interspecies spindle length scaling in Xenopus R Loughlin, JD Wilbur, FJ McNally, FJ Nédélec, R Heald Cell 147 (6), 1397-1407, 2011 | 218 | 2011 |
| TorsinA in PC12 cells: localization in the endoplasmic reticulum and response to stress J Hewett, P Ziefer, D Bergeron, T Naismith, H Boston, D Slater, J Wilbur, ... Journal of neuroscience research 72 (2), 158-168, 2003 | 143 | 2003 |
| Mitotic spindle scaling during Xenopus development by kif2a and importin α JD Wilbur, R Heald Elife 2, e00290, 2013 | 133 | 2013 |
| Clathrin phosphorylation is required for actin recruitment at sites of bacterial adhesion and internalization M Bonazzi, L Vasudevan, A Mallet, M Sachse, A Sartori, MC Prevost, ... Journal of Cell Biology 195 (3), 525-536, 2011 | 127 | 2011 |
| The early onset dystonia protein torsinA interacts with kinesin light chain 1 C Kamm, H Boston, J Hewett, J Wilbur, DP Corey, PI Hanson, V Ramesh, ... Journal of Biological Chemistry 279 (19), 19882-19892, 2004 | 124 | 2004 |
| Actin binding by Hip1 (huntingtin-interacting protein 1) and Hip1R (Hip1-related protein) is regulated by clathrin light chain JD Wilbur, CY Chen, V Manalo, PK Hwang, RJ Fletterick, FM Brodsky Journal of Biological Chemistry 283 (47), 32870-32879, 2008 | 112 | 2008 |
| A comparative analysis of spindle morphometrics across metazoans ME Crowder, M Strzelecka, JD Wilbur, MC Good, G Von Dassow, R Heald Current Biology 25 (11), 1542-1550, 2015 | 101 | 2015 |
| Interplay between spindle architecture and function KJ Helmke, R Heald, JD Wilbur International review of cell and molecular biology 306, 83-125, 2013 | 91 | 2013 |
| Conformation switching of clathrin light chain regulates clathrin lattice assembly JD Wilbur, PK Hwang, JA Ybe, M Lane, BD Sellers, MP Jacobson, ... Developmental cell 18 (5), 854-861, 2010 | 89 | 2010 |
| Clathrin heavy and light chain isoforms originated by independent mechanisms of gene duplication during chordate evolution DE Wakeham, L Abi-Rached, MC Towler, JD Wilbur, P Parham, ... Proceedings of the National Academy of Sciences 102 (20), 7209-7214, 2005 | 81 | 2005 |
| Perinuclear biogenesis of mutant torsin-A inclusions in cultured cells infected with tetracycline-regulated herpes simplex virus type 1 amplicon vectors DC Bragg, SM Camp, CA Kaufman, JD Wilbur, H Boston, DE Schuback, ... Neuroscience 125 (3), 651-661, 2004 | 61 | 2004 |
| New faces of the familiar clathrin lattice JD Wilbur, PK Hwang, FM Brodsky traffic 6 (4), 346-350, 2005 | 47 | 2005 |
| N-terminal phosphorylation of p60 katanin directly regulates microtubule severing E Whitehead, R Heald, JD Wilbur Journal of molecular biology 425 (2), 214-221, 2013 | 46 | 2013 |
| Mutations that alter RcdA surface residues decouple protein localization and CtrA proteolysis in Caulobacter crescentus JA Taylor, JD Wilbur, SC Smith, KR Ryan Journal of molecular biology 394 (1), 46-60, 2009 | 29 | 2009 |
| Identification of GDC-1971 (RLY-1971), a SHP2 inhibitor designed for the treatment of solid tumors AM Taylor, BR Williams, F Giordanetto, EH Kelley, A Lescarbeau, ... Journal of Medicinal Chemistry 66 (19), 13384-13399, 2023 | 13 | 2023 |
| Accommodation of structural rearrangements in the huntingtin-interacting protein 1 coiled-coil domain JD Wilbur, PK Hwang, FM Brodsky, RJ Fletterick Acta Crystallographica Section D: Biological Crystallography 66 (3), 314-318, 2010 | 8 | 2010 |
| Discovery and clinical proof-of-concept of RLY-2608, a first-in-class mutant-selective allosteric PI3Kα inhibitor that decouples antitumor activity from hyperinsulinemia A Varkaris, E Pazolli, H Gunaydin, Q Wang, L Pierce, AA Boezio, A Bulku, ... Cancer Discovery 14 (2), 240-257, 2024 | 7 | 2024 |
| Discovery and characterization of the potent, allosteric SHP2 inhibitor GDC-1971 for the treatment of RTK/RAS driven tumors B Williams, A Taylor, O Orozco, C Owen, E Kelley, A Lescarbeau, ... Cancer Research 82 (12_Supplement), 3327-3327, 2022 | 6 | 2022 |
| Discovery and characterization of RLY-2608: The first allosteric, mutant, and isoform-selective inhibitor of PI3Kα E Pazolli, R Kipp, GH BA, A Iskandar, M Zubrowski Mol Cancer Ther 20 (12 Suppl), P251, 2021 | 6 | 2021 |
| Cryptic no longer: Arrays of CLASP1 TOG domains JD Wilbur, R Heald Structure 21 (6), 869-870, 2013 | 5 | 2013 |
