Liver-resident memory CD8+ T cells form a front-line defense against malaria liver-stage infection D Fernandez-Ruiz, WY Ng, LE Holz, JZ Ma, A Zaid, YC Wong, LS Lau, ... Immunity 45 (4), 889-902, 2016 | 437 | 2016 |
CD8+ T lymphocytes protective against malaria liver stages are primed in skin-draining lymph nodes S Chakravarty, IA Cockburn, S Kuk, MG Overstreet, JB Sacci, F Zavala Nature medicine 13 (9), 1035-1041, 2007 | 352 | 2007 |
A human complement receptor 1 polymorphism that reduces Plasmodium falciparum rosetting confers protection against severe malaria IA Cockburn, MJ Mackinnon, A O'Donnell, SJ Allen, JM Moulds, M Baisor, ... Proceedings of the National Academy of Sciences 101 (1), 272-277, 2004 | 324 | 2004 |
Looking under the skin: the first steps in malarial infection and immunity R Ménard, J Tavares, I Cockburn, M Markus, F Zavala, R Amino Nature Reviews Microbiology 11 (10), 701-712, 2013 | 262 | 2013 |
Virulence of Malaria Is Associated with Differential Expression of Plasmodium falciparum var Gene Subgroups in a Case-Control Study M Kaestli, IA Cockburn, A Cortés, K Baea, JA Rowe, HP Beck The Journal of infectious diseases 193 (11), 1567-1574, 2006 | 203 | 2006 |
Platelet factor 4 mediates inflammation in experimental cerebral malaria K Srivastava, IA Cockburn, AM Swaim, LE Thompson, A Tripathi, ... Cell host & microbe 4 (2), 179-187, 2008 | 187 | 2008 |
B7-H1 Blockade Increases Survival of Dysfunctional CD8+ T Cells and Confers Protection against Leishmania donovani Infections T Joshi, S Rodriguez, V Perovic, IA Cockburn, S Stäger PLoS pathogens 5 (5), e1000431, 2009 | 185 | 2009 |
Protective CD8+ T cells against Plasmodium liver stages: immunobiology of an ‘unnatural’ immune response MG Overstreet, IA Cockburn, YC Chen, F Zavala Immunological reviews 225 (1), 272-283, 2008 | 179 | 2008 |
Up-regulation of LFA-1 allows liver-resident memory T cells to patrol and remain in the hepatic sinusoids HA McNamara, Y Cai, MV Wagle, Y Sontani, CM Roots, LA Miosge, ... Science immunology 2 (9), eaaj1996, 2017 | 168 | 2017 |
The Chemokine Receptor CXCR6 Is Required for the Maintenance of Liver Memory CD8+ T Cells Specific for Infectious Pathogens SW Tse, AJ Radtke, DA Espinosa, IA Cockburn, F Zavala The Journal of infectious diseases 210 (9), 1508-1516, 2014 | 164 | 2014 |
Malaria prevention: from immunological concepts to effective vaccines and protective antibodies IA Cockburn, RA Seder Nature immunology 19 (11), 1199-1211, 2018 | 160 | 2018 |
Atypical B cells are part of an alternative lineage of B cells that participates in responses to vaccination and infection in humans HJ Sutton, R Aye, AH Idris, R Vistein, E Nduati, O Kai, J Mwacharo, X Li, ... Cell reports 34 (6), 2021 | 152 | 2021 |
TFH-derived dopamine accelerates productive synapses in germinal centres I Papa, D Saliba, M Ponzoni, S Bustamante, PF Canete, ... Nature 547 (7663), 318-323, 2017 | 151 | 2017 |
In vivo imaging of CD8+ T cell-mediated elimination of malaria liver stages IA Cockburn, R Amino, RK Kelemen, SC Kuo, SW Tse, A Radtke, ... Proceedings of the National Academy of Sciences 110 (22), 9090-9095, 2013 | 151 | 2013 |
Lymph-Node Resident CD8α+ Dendritic Cells Capture Antigens from Migratory Malaria Sporozoites and Induce CD8+ T Cell Responses AJ Radtke, W Kastenmüller, DA Espinosa, MY Gerner, SW Tse, P Sinnis, ... PLoS pathogens 11 (2), e1004637, 2015 | 118 | 2015 |
Dendritic Cells and Hepatocytes Use Distinct Pathways to Process Protective Antigen from Plasmodium in vivo IA Cockburn, SW Tse, AJ Radtke, P Srinivasan, YC Chen, P Sinnis, ... PLoS pathogens 7 (3), e1001318, 2011 | 117 | 2011 |
A potent anti-malarial human monoclonal antibody targets circumsporozoite protein minor repeats and neutralizes sporozoites in the liver LT Wang, LS Pereira, Y Flores-Garcia, J O’Connor, BJ Flynn, A Schön, ... Immunity 53 (4), 733-744. e8, 2020 | 116 | 2020 |
Prolonged antigen presentation is required for optimal CD8+ T cell responses against malaria liver stage parasites IA Cockburn, YC Chen, MG Overstreet, JR Lees, N van Rooijen, ... PLoS pathogens 6 (5), e1000877, 2010 | 115 | 2010 |
Antibody feedback limits the expansion of B cell responses to malaria vaccination but drives diversification of the humoral response HA McNamara, AH Idris, HJ Sutton, R Vistein, BJ Flynn, Y Cai, K Wiehe, ... Cell host & microbe 28 (4), 572-585. e7, 2020 | 107 | 2020 |
IL-4 receptor expression on CD8+ T cells is required for the development of protective memory responses against liver stages of malaria parasites A Morrot, JCR Hafalla, IA Cockburn, LH Carvalho, F Zavala The Journal of experimental medicine 202 (4), 551-560, 2005 | 104 | 2005 |