Side-chain substitutions within angiotensin II reveal different requirements for signaling, internalization, and phosphorylation of type 1A angiotensin receptors AC Holloway, H Qian, L Pipolo, J Ziogas, S Miura, S Karnik, BR Southwell, ... Molecular pharmacology 61 (4), 768-777, 2002 | 276 | 2002 |
A Novel Mechanism of G Protein-coupled Receptor Functional Selectivity: MUSCARINIC PARTIAL AGONIST McN-A-343 AS A BITOPIC ORTHOSTERIC/ALLOSTERIC LIGAND∗ C Valant, KJ Gregory, NE Hall, PJ Scammells, MJ Lew, PM Sexton, ... Journal of Biological Chemistry 283 (43), 29312-29321, 2008 | 201 | 2008 |
Analysis of competitive agonist-antagonist interactions by nonlinear regression MJ Lew, JA Angus Trends in pharmacological sciences 16 (10), 328-337, 1995 | 181 | 1995 |
Protease-activated receptor 2 (PAR2) protein and transient receptor potential vanilloid 4 (TRPV4) protein coupling is required for sustained inflammatory signaling DP Poole, S Amadesi, NA Veldhuis, FC Abogadie, TM Lieu, W Darby, ... Journal of biological chemistry 288 (8), 5790-5802, 2013 | 172 | 2013 |
Structure-function relationships of ω-conotoxin GVIA: Synthesis, structure, calcium channel binding, and functional assay of alanine-substituted analogues MJ Lew, JP Flinn, PK Pallaghy, R Murphy, SL Whorlow, CE Wright, ... Journal of Biological Chemistry 272 (18), 12014-12023, 1997 | 154 | 1997 |
Hypothalamic norepinephrine: circadian rhythms and the control of feeding behavior DL Margules, MJ Lewis, JA Dragovich, AS Margules Science 178 (4061), 640-643, 1972 | 115 | 1972 |
Good statistical practice in pharmacology Problem 2 M Lew British journal of pharmacology 152 (3), 299-303, 2007 | 106 | 2007 |
Release of endogenous ATP during sympathetic nerve stimulation. MJ Lew, TD White British journal of pharmacology 92 (2), 349, 1987 | 92 | 1987 |
Bad statistical practice in pharmacology (and other basic biomedical disciplines): you probably don't know P MJ Lew British journal of pharmacology 166 (5), 1559-1567, 2012 | 83 | 2012 |
Interpretation of the acetylcholine test of endothelial cell dysfunction in hypertension JA Angus, MJ Lew Journal of Hypertension 10, S187, 1992 | 80 | 1992 |
Roles of key functional groups in ω‐conotoxin GVIA: Synthesis, structure and functional assay of selected peptide analogues JP Flinn, PK Pallaghy, MJ Lew, R Murphy, JA Angus, RS Norton European journal of biochemistry 262 (2), 447-455, 1999 | 76 | 1999 |
The assessment of antagonist potency under conditions of transient response kinetics A Christopoulos, AM Parsons, MJ Lew, EE El-Fakahany European journal of pharmacology 382 (3), 217-227, 1999 | 72 | 1999 |
Arteriolar smooth muscle responses are modulated by an intramural diffusion barrier MJ Lew, RJ Rivers, BR Duling American Journal of Physiology-Heart and Circulatory Physiology 257 (1), H10-H16, 1989 | 63 | 1989 |
N-glycosylation determines ionic permeability and desensitization of the TRPV1 capsaicin receptor NA Veldhuis, MJ Lew, FC Abogadie, DP Poole, EA Jennings, JJ Ivanusic, ... Journal of Biological Chemistry 287 (26), 21765-21772, 2012 | 62 | 2012 |
Pharmacological analysis of cannabinoid receptor activity in the rat vas deferens A Christopoulos, P Coles, L Lay, MJ Lew, JA Angus British journal of pharmacology 132 (6), 1281-1291, 2001 | 59 | 2001 |
Beyond eyeballing: fitting models to experimental data A Christopoulos, MJ Lew Critical Reviews in Biochemistry and Molecular Biology 35 (5), 359-391, 2000 | 59 | 2000 |
Dynamic mechanisms of non-classical antagonism by competitive AT1 receptor antagonists MJ Lew, J Ziogas, A Christopoulos Trends in Pharmacological Sciences 21 (10), 376-381, 2000 | 55 | 2000 |
Wall thickness to lumen diameter ratios of arteries from SHR and WKY: comparison of pressurised and wire-mounted preparations MJ Lew, JA Angus Journal of vascular research 29 (6), 435-442, 1992 | 52 | 1992 |
Role of disulfide bridges in the folding, structure and biological activity of ω-conotoxin GVIA JP Flinn, PK Pallaghy, MJ Lew, R Murphy, JA Angus, RS Norton Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 1999 | 43 | 1999 |
Mechanisms of melatonin‐induced vasoconstriction in the rat tail artery: a paradigm of weak vasoconstriction MJ Lew, S Flanders British journal of pharmacology 126 (6), 1408-1418, 1999 | 40 | 1999 |