| The Nuclear Orphan Receptor CAR-Retinoid X Receptor Heterodimer Activates the Phenobarbital-Responsive Enhancer Module of the CYP2B Gene P Honkakoski, I Zelko, T Sueyoshi, M Negishi Molecular and cellular biology 18 (10), 5652-5658, 1998 | 897 | 1998 |
| The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene T Sueyoshi, T Kawamoto, I Zelko, P Honkakoski, M Negishi Journal of Biological Chemistry 274 (10), 6043-6046, 1999 | 845 | 1999 |
| Inhibition and induction of human cytochrome P450 enzymes: current status O Pelkonen, M Turpeinen, J Hakkola, P Honkakoski, J Hukkanen, ... Archives of toxicology 82, 667-715, 2008 | 701 | 2008 |
| Regulation of cytochrome P450 (CYP) genes by nuclear receptors P Honkakoski, M Negishi Biochemical Journal 347 (2), 321-337, 2000 | 659 | 2000 |
| Extracellular glycosaminoglycans modify cellular trafficking of lipoplexes and polyplexes M Ruponen, S Rönkkö, P Honkakoski, J Pelkonen, M Tammi, A Urtti Journal of Biological Chemistry 276 (36), 33875-33880, 2001 | 264 | 2001 |
| Drug-activated nuclear receptors CAR and PXR P Honkakoski, T Sueyoshi, M Negishi Annals of medicine 35 (3), 172-182, 2003 | 230 | 2003 |
| Extracellular and intracellular barriers in non-viral gene delivery M Ruponen, P Honkakoski, S Rönkkö, J Pelkonen, M Tammi, A Urtti Journal of controlled release 93 (2), 213-217, 2003 | 219 | 2003 |
| Activation by diverse xenochemicals of the 51-base pair phenobarbital-responsive enhancer module in the CYP2B10Gene P Honkakoski, R Moore, KA Washburn, M Negishi Molecular Pharmacology 53 (4), 597-601, 1998 | 217 | 1998 |
| Characterization of a phenobarbital-responsive enhancer module in mouse P450 Cyp2b10 gene P Honkakoski, M Negishi Journal of Biological Chemistry 272 (23), 14943-14949, 1997 | 207 | 1997 |
| High variability of nitrosamine metabolism among individuals: Role of cytochromes P450 2A6 and 2E1 in the dealkylation of N‐nitrosodimethylamine and N‐nitrosodiethylamine in … AM Camus, O Geneste, P Honkakoski, JC Béréziat, CJ Henderson, ... Molecular carcinogenesis 7 (4), 268-275, 1993 | 182 | 1993 |
| Substrates and inhibitors of efflux proteins interfere with the MTT assay in cells and may lead to underestimation of drug toxicity KS Vellonen, P Honkakoski, A Urtti European journal of pharmaceutical sciences 23 (2), 181-188, 2004 | 159 | 2004 |
| Immunochemical and catalytical studies on hepatic coumarin 7-hydroxylase in man, rat, and mouse H Raunio, T Syngelmä, M Pasanen, R Juvonen, P Honkakoski, ... Biochemical pharmacology 37 (20), 3889-3895, 1988 | 147 | 1988 |
| Cell‐surface glycosaminoglycans inhibit cation‐mediated gene transfer M Ruponen, P Honkakoski, M Tammi, A Urtti The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2004 | 139 | 2004 |
| Characterization of phenobarbital-inducible mouse Cyp2b10 gene transcription in primary hepatocytes P Honkakoski, R Moore, J Gynther, M Negishi Journal of Biological Chemistry 271 (16), 9746-9753, 1996 | 138 | 1996 |
| Peptide− oligonucleotide phosphorothioate conjugates with membrane translocation and nuclear localization properties M Antopolsky, E Azhayeva, U Tengvall, S Auriola, I Jääskeläinen, ... Bioconjugate chemistry 10 (4), 598-606, 1999 | 127 | 1999 |
| Protein serine/threonine phosphatase inhibitors suppress phenobarbital-induced Cyp2b10 gene transcription in mouse primary hepatocytes P HONKAKOSKI, M NEGISHI Biochemical Journal 330 (2), 889-895, 1998 | 127 | 1998 |
| Mouse steroid 15. alpha.-hydroxylase gene family: identification of type II P-45015. alpha. as coumarin 7-hydroxylase M Negishi, R Lindberg, B Burkhart, T Ichikawa, P Honkakoski, M Lang Biochemistry 28 (10), 4169-4172, 1989 | 126 | 1989 |
| Cocaine N-demethylation and the metabolism-related hepatotoxicity can be prevented by cytochrome P450 3A inhibitors P Pellinen, P Honkakoski, F Stenbäck, M Niemitz, E Alhava, O Pelkonen, ... European Journal of Pharmacology: Environmental Toxicology and Pharmacology …, 1994 | 117 | 1994 |
| Towards personalized medicine with a three-dimensional micro-scale perfusion-based two-chamber tissue model system L Ma, J Barker, C Zhou, W Li, J Zhang, B Lin, G Foltz, J Küblbeck, ... Biomaterials 33 (17), 4353-4361, 2012 | 108 | 2012 |
| Characterization of human cytochrome P450 induction by pesticides K Abass, V Lämsä, P Reponen, J Küblbeck, P Honkakoski, S Mattila, ... Toxicology 294 (1), 17-26, 2012 | 105 | 2012 |
Arto UrttiUniversity of Helsinki在 helsinki.fi 的电子邮件经过验证
