A structural classification of substrate-binding proteins RPA Berntsson, SHJ Smits, L Schmitt, DJ Slotboom, B Poolman FEBS letters 584 (12), 2606-2617, 2010 | 584 | 2010 |
Role of the extremolytes ectoine and hydroxyectoine as stress protectants and nutrients: genetics, phylogenomics, biochemistry, and structural analysis L Czech, L Hermann, N Stöveken, AA Richter, A Höppner, SHJ Smits, ... Genes 9 (4), 177, 2018 | 223 | 2018 |
A Novel Polyester Hydrolase From the Marine Bacterium Pseudomonas aestusnigri – Structural and Functional Insights A Bollinger, S Thies, E Knieps-Grünhagen, C Gertzen, S Kobus, ... Frontiers in microbiology 11, 114, 2020 | 213 | 2020 |
Crystal structure of the Lrp‐like transcriptional regulator from the archaeon Pyrococcus furiosus PM Leonard, SHJ Smits, SE Sedelnikova, AB Brinkman, WM de Vos, ... The EMBO journal, 2001 | 178 | 2001 |
Crystal structures of the choline/acetylcholine substrate-binding protein ChoX from Sinorhizobium meliloti in the liganded and unliganded-closed states C Oswald, SHJ Smits, M Hoing, L Sohn-Bosser, L Dupont, D Le Rudulier, ... Journal of Biological Chemistry 283 (47), 32848-32859, 2008 | 116 | 2008 |
Biochemical properties of ectoine hydroxylases from extremophiles and their wider taxonomic distribution among microorganisms N Widderich, A Hoeppner, M Pittelkow, J Heider, SHJ Smits, E Bremer PloS one 9 (4), e93809, 2014 | 97 | 2014 |
Lantibiotics: how do producers become self-protected? Z Alkhatib, A Abts, A Mavaro, L Schmitt, SHJ Smits Journal of biotechnology 159 (3), 145-154, 2012 | 90 | 2012 |
The rate of folding dictates substrate secretion by the Escherichia coli hemolysin type 1 secretion system PJ Bakkes, S Jenewein, SHJ Smits, IB Holland, L Schmitt Journal of Biological Chemistry 285 (52), 40573-40580, 2010 | 87 | 2010 |
An RTX transporter tethers its unfolded substrate during secretion via a unique N-terminal domain J Lecher, CKW Schwarz, M Stoldt, SHJ Smits, D Willbold, L Schmitt Structure 20 (10), 1778-1787, 2012 | 75 | 2012 |
NisC binds the FxLx motif of the nisin leader peptide A Abts, M Montalban-Lopez, OP Kuipers, SH Smits, L Schmitt Biochemistry 52 (32), 5387-5395, 2013 | 73 | 2013 |
Substrate recognition and specificity of the NisB protein, the lantibiotic dehydratase involved in nisin biosynthesis A Mavaro, A Abts, PJ Bakkes, GN Moll, AJM Driessen, SHJ Smits, ... Journal of Biological Chemistry 286 (35), 30552-30560, 2011 | 71 | 2011 |
pH‐induced structural change in a sodium/proton antiporter from Methanococcus jannaschii KR Vinothkumar, SHJ Smits, W Kühlbrandt The EMBO Journal 24 (15), 2720-2729, 2005 | 71 | 2005 |
The GTPase activity of murine guanylate-binding protein 2 (mGBP2) controls the intracellular localization and recruitment to the parasitophorous vacuole of Toxoplasma gondii E Kravets, D Degrandi, S Weidtkamp-Peters, B Ries, C Konermann, ... Journal of Biological Chemistry 287 (33), 27452-27466, 2012 | 67 | 2012 |
The Compatible-Solute-Binding Protein OpuAC from Bacillus subtilis: Ligand Binding, Site-Directed Mutagenesis, and Crystallographic Studies SHJ Smits, M Höing, J Lecher, M Jebbar, L Schmitt, E Bremer Journal of bacteriology 190 (16), 5663-5671, 2008 | 67 | 2008 |
The crystal structure of the substrate-binding protein OpuBC from Bacillus subtilis in complex with choline M Pittelkow, B Tschapek, SHJ Smits, L Schmitt, E Bremer Journal of molecular biology 411 (1), 53-67, 2011 | 65 | 2011 |
NSR from Streptococcus agalactiae confers resistance against nisin and is encoded by a conserved nsr operon S Khosa, Z AlKhatib, SHJ Smits Biological chemistry 394 (11), 1543-1549, 2013 | 64 | 2013 |
Easy and rapid purification of highly active nisin A Abts, A Mavaro, J Stindt, PJ Bakkes, S Metzger, AJM Driessen, ... International Journal of Peptides 2011 (1), 175145, 2011 | 64 | 2011 |
Structure and efflux mechanism of the yeast pleiotropic drug resistance transporter Pdr5 A Harris, M Wagner, D Du, S Raschka, LM Nentwig, H Gohlke, SHJ Smits, ... Nature communications 12 (1), 5254, 2021 | 63 | 2021 |
Arsenobetaine: an ecophysiologically important organoarsenical confers cytoprotection against osmotic stress and growth temperature extremes T Hoffmann, B Warmbold, SHJ Smits, B Tschapek, S Ronzheimer, ... Environmental microbiology 20 (1), 305-323, 2018 | 62 | 2018 |
Biosynthesis of the stress-protectant and chemical chaperon ectoine: biochemistry of the transaminase EctB AA Richter, CN Mais, L Czech, K Geyer, A Hoeppner, SHJ Smits, TJ Erb, ... Frontiers in microbiology 10, 2811, 2019 | 59 | 2019 |