Sulfur and selenium: the role of oxidation state in protein structure and function C Jacob, GI Giles, NM Giles, H Sies Angewandte Chemie International Edition 42 (39), 4742-4758, 2003 | 892 | 2003 |
Metal and redox modulation of cysteine protein function NM Giles, AB Watts, GI Giles, FH Fry, JA Littlechild, C Jacob Chemistry & biology 10 (8), 677-693, 2003 | 537 | 2003 |
Reactive sulfur species: an emerging concept in oxidative stress GI Giles, C Jacob Walter de Gruyter 383 (3-4), 375-388, 2002 | 377 | 2002 |
Hypothesis: the role of reactive sulfur species in oxidative stress GI Giles, KM Tasker, C Jacob Free Radical Biology and Medicine 31 (10), 1279-1283, 2001 | 335 | 2001 |
Multiple roles of cysteine in biocatalysis NM Giles, GI Giles, C Jacob Biochemical and biophysical research communications 300 (1), 1-4, 2003 | 246 | 2003 |
Mycobacterium tuberculosis WhiB3 responds to O2 and nitric oxide via its [4Fe-4S] cluster and is essential for nutrient starvation survival A Singh, L Guidry, KV Narasimhulu, D Mai, J Trombley, KE Redding, ... Proceedings of the National Academy of Sciences 104 (28), 11562-11567, 2007 | 228 | 2007 |
The redox regulation of thiol dependent signaling pathways in cancer GI Giles Current pharmaceutical design 12 (34), 4427-4443, 2006 | 225 | 2006 |
Fatty acid transduction of nitric oxide signaling: nitrolinoleic acid is a hydrophobically stabilized nitric oxide donor FJ Schopfer, PRS Baker, G Giles, P Chumley, C Batthyany, J Crawford, ... Journal of Biological Chemistry 280 (19), 19289-19297, 2005 | 206 | 2005 |
A Fungal Metallothionein Is Required for Pathogenicity of Magnaporthe grisea SL Tucker, CR Thornton, K Tasker, C Jacob, G Giles, M Egan, NJ Talbot The Plant Cell 16 (6), 1575-1588, 2004 | 128 | 2004 |
Xanthine oxidase–dependent regulation of hypoxia-inducible factor in cancer cells CE Griguer, CR Oliva, EE Kelley, GI Giles, JR Lancaster Jr, GY Gillespie Cancer research 66 (4), 2257-2263, 2006 | 113 | 2006 |
Moderate hypoxia induces xanthine oxidoreductase activity in arterial endothelial cells EE Kelley, T Hock, NKH Khoo, GR Richardson, KK Johnson, PC Powell, ... Free Radical Biology and Medicine 40 (6), 952-959, 2006 | 102 | 2006 |
Electrochemical and in vitro evaluation of the redox-properties of kynurenine species GI Giles, CA Collins, TW Stone, C Jacob Biochemical and Biophysical Research Communications 300 (3), 719-724, 2003 | 99 | 2003 |
Topoisomerase enzymes as therapeutic targets for cancer chemotherapy GI Giles, RP Sharma Medicinal Chemistry 1 (4), 383-394, 2005 | 96 | 2005 |
The reactive sulfur species concept: 15 years on GI Giles, MJ Nasim, W Ali, C Jacob Antioxidants 6 (2), 38, 2017 | 95 | 2017 |
Biologically active [Pd 2 L 4] 4+ quadruply-stranded helicates: stability and cytotoxicity SM McNeill, D Preston, JEM Lewis, A Robert, K Knerr-Rupp, DO Graham, ... Dalton Transactions 44 (24), 11129-11136, 2015 | 95 | 2015 |
Evaluation of sulfur, selenium and tellurium catalysts with antioxidant potential GI Giles, FH Fry, KM Tasker, AL Holme, C Peers, KN Green, LO Klotz, ... Organic & biomolecular chemistry 1 (23), 4317-4322, 2003 | 93 | 2003 |
Reactive sulphur species: an in vitro investigation of the oxidation properties of disulphide S-oxides GI Giles, KM Tasker, C Collins, NM Giles, E O'rourke, C Jacob Biochemical Journal 364 (2), 579-585, 2002 | 92 | 2002 |
Controlled delivery of nitric oxide for cancer therapy H Alimoradi, K Greish, AB Gamble, GI Giles Pharmaceutical nanotechnology 7 (4), 279-303, 2019 | 89 | 2019 |
Schwefel und selen: bedeutung der oxidationsstufe für struktur und funktion von proteinen C Jacob, GI Giles, NM Giles, H Sies Angewandte Chemie 115 (39), 4890-4907, 2003 | 72 | 2003 |
Oxidation of biological thiols by highly reactive disulfide-S-oxides GI Giles, KM Tasker, C Jacob General physiology and biophysics 21 (1), 65-72, 2002 | 68 | 2002 |