A multivariate raw material property database to facilitate drug product development and enable in-silico design of pharmaceutical dry powder processes B Van Snick, J Dhondt, K Pandelaere, J Bertels, R Mertens, D Klingeleers, ... International journal of pharmaceutics 549 (1-2), 415-435, 2018 | 95 | 2018 |
A multivariate approach to predict the volumetric and gravimetric feeding behavior of a low feed rate feeder based on raw material properties N Bostijn, J Dhondt, A Ryckaert, E Szabó, W Dhondt, B Van Snick, ... International journal of pharmaceutics 557, 342-353, 2019 | 66 | 2019 |
Development of a process map: A step towards a regime map for steady-state high shear wet twin screw granulation A Kumar, J Dhondt, J Vercruysse, F De Leersnyder, V Vanhoorne, ... Powder technology 300, 73-82, 2016 | 57 | 2016 |
Impact of material properties and process variables on the residence time distribution in twin screw feeding equipment B Van Snick, A Kumar, M Verstraeten, K Pandelaere, J Dhondt, ... International journal of pharmaceutics 556, 200-216, 2019 | 54 | 2019 |
Impact of blend properties on die filling during tableting B Van Snick, W Grymonpré, J Dhondt, K Pandelaere, G Di Pretoro, ... International Journal of Pharmaceutics 549 (1-2), 476-488, 2018 | 53 | 2018 |
Evaluation of an in-line particle imaging tool for monitoring twin-screw granulation performance A Kumar, J Dhondt, F De Leersnyder, J Vercruysse, V Vanhoorne, ... Powder Technology 285, 80-87, 2015 | 30 | 2015 |
Determination of a quantitative relationship between material properties, process settings and screw feeding behavior via multivariate data-analysis B Bekaert, L Penne, W Grymonpré, B Van Snick, J Dhondt, J Boeckx, ... International Journal of Pharmaceutics 602, 120603, 2021 | 21 | 2021 |
A multivariate formulation and process development platform for direct compression J Dhondt, J Bertels, A Kumar, D Van Hauwermeiren, A Ryckaert, ... International Journal of Pharmaceutics 623, 121962, 2022 | 17 | 2022 |
In-depth analysis of the long-term processability of materials during continuous feeding B Bekaert, B Van Snick, K Pandelaere, J Dhondt, G Di Pretoro, T De Beer, ... International Journal of Pharmaceutics 614, 121454, 2022 | 13 | 2022 |
Continuous direct compression: Development of an empirical predictive model and challenges regarding PAT implementation B Bekaert, B Van Snick, K Pandelaere, J Dhondt, G Di Pretoro, T De Beer, ... International Journal of Pharmaceutics: X 4, 100110, 2022 | 11 | 2022 |
TPLS as predictive platform for twin-screw wet granulation process and formulation development A Ryckaert, D Van Hauwermeiren, J Dhondt, A De Man, A Funke, D Djuric, ... International Journal of Pharmaceutics 605, 120785, 2021 | 11 | 2021 |
A multivariate methodology for material sparing characterization and blend design in drug product development J Dhondt, Y Eeckhout, J Bertels, A Kumar, B Van Snick, D Klingeleers, ... International Journal of Pharmaceutics 621, 121801, 2022 | 8 | 2022 |
Powder filling of electrospun material in vials: A proof-of-concept study E Szabó, P Záhonyi, DL Galata, L Madarász, P Vass, A Farkas, J Dhondt, ... International Journal of Pharmaceutics 613, 121413, 2022 | 2 | 2022 |
Development of regime map for steady-state high shear wet twin-screw granulation A Kumar, J Dhont, J Vercruysse, F De Leersnyder, V Vanhoorne, ... 7th International Granulation Workshop, 236-245, 2015 | 2 | 2015 |
A predictive tableting platform for direct compression processes J Dhondt Ghent University, 2021 | | 2021 |
The Use of T-PLS to Investigate the IMPACT of Raw Material Properties on Granule Quality Attributes Obtained after Continuous Twin-SCREW WET Granulation A Ryckaert, J Dhondt, T De Beer 2019 AIChE Annual Meeting, 2019 | | 2019 |
Multivariate Data Analysis of Raw Material Properties from Pharmaceutical Powders for Predicting Compaction Behavior Using Finite Element Method J Dhondt, A Kumar, B Van Snick, J Bertels, D Klingeleers, C Vervaet, ... 2017 AIChE Annual Meeting, 2017 | | 2017 |
Leveraging Raw Material and Blend Properties with the Die Filling Step of the Tableting Process V Vanhoorne, B Van Snick, J Dhondt, C Segers, K Van Vooren, ... 2017 AIChE Annual Meeting, 2017 | | 2017 |
Impact of Raw Material and Blend Properties on the Screw Feeding, Continuous Blending and Tableting Unit Operation of an Integrated Continuous Direct Compression Platform B Van Snick, V Vanhoorne, M Verstraeten, J Dhondt, G Di Pretoro, ... 2017 AIChE Annual Meeting, 2017 | | 2017 |
Visualization of compaction behavior of pharmaceutical powders in solid-dosage manufacturing using finite element analysis A Kumar, J Dhondt, J Bertels, D Klingeleers, KV Gernaey, I Nopens, ... Compaction Simulation Forum 2017, 2017 | | 2017 |