| The complement system: an unexpected role in synaptic pruning during development and disease AH Stephan, BA Barres, B Stevens Annual review of neuroscience 35, 369-389, 2012 | 1089 | 2012 |
| A dramatic increase of C1q protein in the CNS during normal aging AH Stephan, DV Madison, JM Mateos, DA Fraser, EA Lovelett, ... Journal of Neuroscience 33 (33), 13460-13474, 2013 | 414 | 2013 |
| Neurotrypsin cleaves agrin locally at the synapse A Stephan, JM Mateos, SV Kozlov, P Cinelli, AD Kistler, S Hettwer, ... The FASEB Journal 22 (6), 1861-1873, 2008 | 151 | 2008 |
| Specific proteolytic cleavage of agrin regulates maturation of the neuromuscular junction MF Bolliger, A Zurlinden, D Lüscher, L Bütikofer, O Shakhova, ... Journal of cell science 123 (22), 3944-3955, 2010 | 125 | 2010 |
| Specific cleavage of agrin by neurotrypsin, a synaptic protease linked to mental retardation R Reif, S Sales, S Hettwer, B Dreier, C Gisler, J Wölfel, D Lüscher, ... The FASEB Journal 21 (13), 3468-3478, 2007 | 115 | 2007 |
| Activity-induced synaptic capture and exocytosis of the neuronal serine protease neurotrypsin R Frischknecht, A Fejtova, M Viesti, A Stephan, P Sonderegger Journal of Neuroscience 28 (7), 1568-1579, 2008 | 107 | 2008 |
| Impaired prenatal motor axon development necessitates early therapeutic intervention in severe SMA L Kong, DO Valdivia, CM Simon, CW Hassinan, N Delestrée, DR Ramos, ... Science Translational Medicine 13 (578), 2021 | 67 | 2021 |
| Reduced removal of synaptic terminals from axotomized spinal motoneurons in the absence of complement C3 A Berg, J Zelano, A Stephan, S Thams, BA Barres, M Pekny, M Pekna, ... Experimental neurology 237 (1), 8-17, 2012 | 66 | 2012 |
| Risdiplam, the First Approved Small Molecule Splicing Modifier Drug as a Blueprint for Future Transformative Medicines H Ratni, RS Scalco, AH Stephan ACS Medicinal Chemistry Letters, 2021 | 53 | 2021 |
| Molecular characterization of a trafficking organelle: Dissecting the axonal paths of calsyntenin‐1 transport vesicles M Steuble, B Gerrits, A Ludwig, JM Mateos, TM Diep, M Tagaya, ... Proteomics 10 (21), 3775-3788, 2010 | 37 | 2010 |
| Modulation of synaptic maintenance BA Barres, AH Stephan, BA Stevens US Patent 9,480,658, 2016 | 32 | 2016 |
| Modulation of Synaptic Maintenance BA Barres, AH Stephan, BA Stevens US Patent 20,120,328,601, 2012 | 32* | 2012 |
| Emergence of lamina-specific retinal ganglion cell connectivity by axon arbor retraction and synapse elimination TW Cheng, XB Liu, RL Faulkner, AH Stephan, BA Barres, AD Huberman, ... Journal of Neuroscience 30 (48), 16376-16382, 2010 | 24 | 2010 |
| Nocturnal accumulation of cyclic 3′, 5′‐guanosine monophosphate (cGMP) in the chick pineal organ is dependent on activation of guanylyl cyclase‐B J Olcese, C Majora, A Stephan, D Müller Journal of neuroendocrinology 14 (1), 14-18, 2002 | 10 | 2002 |
| Modulation of synaptic maintenance BA Barres, AH Stephan, BA Stevens US Patent 10,240,156, 2019 | 4 | 2019 |
| Method for the detection of the in-vivo activity of neurotrypsin, use of the method and use of the c-terminal, 22-kda fragment of agrin as biomarker in diagnosis and monitoring … P Sonderegger, S Hettwer, A Stephan, K Miyai, B Kunz US Patent App. 12/599,456, 2010 | 2 | 2010 |
| Method for the detection of the in-vivo activity of neurotrypsin, use of the method and use of the c-terminal, 22-kda fragment of agrin as biomarker in diagnosis and monitoring … P Sonderegger, S Hettwer, A Stephan, K Miyai, B Kunz US Patent App. 12/599,456, 2010 | 2 | 2010 |
| Method for the detection of the in-vivo activity of neurotrypsin, use of the method and use of the c-terminal, 22-kda fragment of agrin as biomarker in diagnosis and monitoring … P Sonderegger, S Hettwer, A Stephan, K Miyai, B Kunz US Patent App. 12/599,456, 2010 | 2 | 2010 |
| A role for C1q in normal brain aging AH Stephan, DV Madison, JM Mateos, D Fraser, L Coutellier, E Lovelett, ... Immunobiology 217 (11), 1133, 2012 | 1 | 2012 |
| SMN2 Splicing Modification by Small Molecules–A Blueprint to Tackle the Underlying Genetic Cause of Many Underserved Diseases H Ratni, M Ebeling, RS Scalco, L Mueller, A Stephan The Handbook of Medicinal Chemistry, 830-846, 2023 | | 2023 |
